- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory and Cough-Related Research
- Asthma and respiratory diseases
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Schizophrenia research and treatment
- Eosinophilic Disorders and Syndromes
- IL-33, ST2, and ILC Pathways
- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Hernia repair and management
- Pulmonary Hypertension Research and Treatments
- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Urologic and reproductive health conditions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Stoma care and complications
- Sperm and Testicular Function
- Genetic Associations and Epidemiology
- Sarcoidosis and Beryllium Toxicity Research
- Muscle and Compartmental Disorders
- Protein Degradation and Inhibitors
Methodist Hospital
2023-2024
McMaster University
2019-2023
Nationwide Children's Hospital
2023
Harvard University
2022
General Department of Preventive Medicine
2022
Dalhousie University
2022
University of Ottawa
2022
Case Western Reserve University
2020-2021
University School
2020
Cleveland Clinic
2019-2020
The objective of this study was to examine the prevalence and patterns antipsychotic use in children adolescents at time admission discharge from a tertiary care inpatient psychiatric facility. This retrospective analysis included all patients 18 years younger, who were admitted discharged child adolescent facility between May 1, 2008 December 31, 2009. Data for medications obtained using province-wide network that links pharmacies British Columbia, Canada central set data systems, whereas...
We report the case of a 65-year-old woman who presented with left-sided flank pain and was discovered to have right ureteroduodenal fistula likely secondary an impacted stone that eroded into duodenum. also discuss management this patient.
Antipsychotics are the first-line agents for managing schizophrenia and related disorders. As with other chronic illnesses, clinicians must often decide whether to switch a patient’s current medication try improve treatment response, reduce intolerable side effects quality of
Background: The incidence of acute kidney injury (AKI) in patients with COVID-19 and its association mortality disease severity is understudied the Canadian population. Objective: To determine AKI a cohort admitted to medicine intensive care unit (ICU) wards, in-hospital mortality, severity. Our aim was stratify these outcomes by out-of-hospital AKI. Design: Retrospective study from registry COVID-19. Setting: Three community 3 academic hospitals. Patients: A total 815 hospital between March...
Although the lack of information on costs and pricing healthcare services prevails throughout medical industry, empiric observations have demonstrated that is even more obscured in sperm cryopreservation market. Thus, objectives our study are to assess compare online price transparency across various settings United States. This examined published by facilities an active registration store spermatozoa with Food Drug Administration. Less than one-fifth registered display any online. Price...
INTRODUCTION: Atypical teratoid rhabdoid tumors (ATRTs) are molecularly-defined by deletions or mutations in tumor suppressor INI1. INI1 deficiency causes dysfunction of chromatin-remodeling complexes which normally oppose EZH2, a epigenetic gene silencing protein. In the setting deficiency, EZH2 is over-expressed, leading to ATRT oncogenesis. Using novel patient-derived orthotopic xenograft (PDOX) models, we investigated pre-clinical utility therapeutic inhibition using drug DZNep. METHODS:...
Sperm granuloma is a common finding following vasectomy, with majority of the lesions located at site vasectomy defect. granulomas are typically small and asymptomatic. We describe case in which nodule presented similarly to supernumerary testis by radiographic features.
While intradetrusor botulinum neurotoxin (BoNT) injection is a well-established treatment of neurogenic detrusor overactivity, its administration in individuals with complex genitourinary (GU) reconstruction can be difficult. The objective this report to highlight our institution's experience challenges and practical solutions delivering BoNT unique patient population. We performed retrospective review database adults congenital lower urinary tract dysfunction (NLUTD) history GU who received...
Abstract Objectives The objective of this study is to explore the functional connectivity (FC) cerebellum during storage phase micturition, through detecting spontaneous blood‐oxygen‐level dependent signal between and different brain regions using a high‐resolution 7 Tesla magnetic resonance imaging (MRI) scanner. Materials Methods We recruited healthy individuals with no reported history neurological disease or lower urinary tract (LUT) symptoms. Participants were asked drink 500 mL water...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Neurogenic Voiding Dysfunction (PD07)1 May 2024PD07-06 DIFFERENCES IN FUNCTIONAL CONNECTIVITY OF CEREBELLAR REGIONS INVOLVED CONTROL BLADDER FUNCTION WOMEN WITH MULTIPLE SCLEROSIS AND VOIDING DYSFUNCTION Johnny S. Su, Kris A. Hoffman, Charles Mazeaud, Betsy H. Salazar, Christof Karmonik, and Rose Khavari SuJohnny Su , HoffmanKris Hoffman MazeaudCharles Mazeaud SalazarBetsy Salazar...
Accumulating evidences suggest that recurrent tumors may acquire genetic abnormalities different from their treatment naive counterparts. Since surgery is rarely an option for terminal brain tumors, autopsy frequently the only chance to obtain therapy resistant tumor tissues. To determine and if (some) cells can survival postmortem anoxia/starvation identify seed repopulate orthotopic xenograft we collected 29 autopsied including 15 DIPGs, 7 GBMs, 4 medulloblastomas (MB), 2 ependymomas 1...
INTRODUCTION: Recent genomic studies have provided significant insight into the pathogenesis of pediatric central nervous system (CNS) tumors. However, little is known about genetic events underlying rare CNS tumor types, which often present diagnostic and therapeutic challenges. The BASIC3 clinical exome sequencing study children with newly-diagnosed tumors offers an opportunity to investigate basis these METHODS: Tumor germline whole (WES) performed in a CLIA-certified laboratory on...