A5054769626- Immune cells in cancer
- S100 Proteins and Annexins
- Acute Ischemic Stroke Management
- MicroRNA in disease regulation
- NF-κB Signaling Pathways
- Neurological Disorders and Treatments
- Peroxisome Proliferator-Activated Receptors
- Hepatitis B Virus Studies
- Cancer, Hypoxia, and Metabolism
- Vitamin C and Antioxidants Research
- Circular RNAs in diseases
- Inflammatory mediators and NSAID effects
- Extracellular vesicles in disease
- Systemic Lupus Erythematosus Research
- Diabetes and associated disorders
- Cancer-related molecular mechanisms research
- Infectious Encephalopathies and Encephalitis
- Cancer, Lipids, and Metabolism
- Neurological Disease Mechanisms and Treatments
- Adipose Tissue and Metabolism
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammasome and immune disorders
- Antioxidant Activity and Oxidative Stress
- Bacterial Infections and Vaccines
Biotechnology Research Center
2024
Pasteur Institute of Iran
2024
Golestan University of Medical Sciences
2019-2023
Golestan University
2019-2023
Abstract Background Stroke , either due to ischemia or hemorrhage causes acute neurological damages the brain. There is shortage of reliable biomarkers for ischemic stroke (IS), and we therefore investigated serum concentrations microRNA‐210 (miR‐210) hypoxia inducible factor‐1α (HIF‐1α), as possible diagnostic and/or prognostic markers IS. Methods Serum samples were acquired from 52 IS patients their healthy counterparts at five time points: upon admission, 24 48 h after discharge 3 months...
Doxorubicin (DOX) is a common chemotherapeutic agent, with toxic side effects, and chemoresistance. Combination chemotherapy successful approach to overcome these limitations. Here, we investigated the effects of pioglitazone (PGZ), PPARγ agonist, and/or DOX on viability, cell cycle, apoptosis THP-1 cells normal human monocytes (NHMs).MTT assay was used evaluate cytotoxicity PGZ. Cell cycle progression induction were examined by PI or Annexin V-PI double staining, analyzed flow cytometry....
Abstract Introduction Oxidative stress known as a predictive marker for cardiovascular and metabolic diseases could be measured through pro‐oxidant antioxidant balance (PAB). The present study aimed to evaluate PAB its association with high‐sensitivity C‐reactive protein (hs‐CRP) in the serum of postmenopausal women diabetes mellitus. Methods In this case–control study, 99 diabetic 100 healthy without mellitus were recruited. Serum values, hs‐CRP, lipid profile, insulin, vitamin D levels...
Chronic hepatitis B (CHB) poses treatment challenges, with response and disease outcome often determined by the immune response, particularly mononuclear phagocytes. Monocytes can differentiate into various subpopulations influenced AHR. Statins, known for inflammation modulation, may impact monocyte function via AHR activation. This study explored rosuvastatin (RSV)’s effects on subtypes, inflammatory markers, in CHB patients. Fifteen patients were randomly assigned to receive either 20 mg...
(FS) is a neuroinflammatory disease involving fever-induced seizures affecting children in the early stages of life. TNFα pro-inflammatory cytokine reported to be elevated FS. Specific promoter variants