A5049071565- Radio Frequency Integrated Circuit Design
- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Microwave Engineering and Waveguides
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Microwave and Dielectric Measurement Techniques
- Radar Systems and Signal Processing
- Antenna Design and Optimization
- Advanced Power Amplifier Design
- Electrochemical Analysis and Applications
- Semiconductor Quantum Structures and Devices
- Full-Duplex Wireless Communications
- Ocular and Laser Science Research
- Dye analysis and toxicity
- Diamond and Carbon-based Materials Research
- Smart Grid Energy Management
- Distributed and Parallel Computing Systems
- Photonic and Optical Devices
- Integrated Energy Systems Optimization
- Identification and Quantification in Food
- Microfluidic and Capillary Electrophoresis Applications
- Acoustic Wave Resonator Technologies
- Microwave Imaging and Scattering Analysis
- Innovative Microfluidic and Catalytic Techniques Innovation
CiS Research Institute for Micro Sensors and Photovoltaics
2020-2022
Leibniz Institute of Photonic Technology
2015-2021
Helmholtz Institute Jena
2014-2021
InfectoGnostics Research Campus Jena
2019-2021
Friedrich Schiller University Jena
2014-2020
Albert Einstein College of Medicine
2019
Europa-Universität Flensburg
2018-2019
Johannes Kepler University of Linz
2008-2015
Institute of Physical Chemistry
2014-2015
Siemens (Austria)
2014
Considering both the potential effects on human health and need for knowledge of food composition, quantitative detection synthetic dyes in foodstuffs beverages is an important issue. For first time, we report a fast analysis drink colorant azorubine (E 122) different types using surface-enhanced Raman scattering (SERS) without any sample preparation. Seven commercially available sweet drinks (including two negative controls) with high levels complexity (sugar/artificial sweetener, ethanol...
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRaman Spectroscopy and Imaging in BioanalyticsDana Cialla-MayDana Cialla-MayLeibniz-Institute of Photonic Technology, Member the Leibniz Research Alliance − Health Technologies, Albert-Einstein-Str. 9, 07745 Jena, GermanyInstitute Physical Chemistry Abbe Center Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 GermanyInfectoGnostics Campus Applied Research, Philosophenweg 7, GermanyMore by Dana Cialla-MayView Biography, Christoph...
The pharmacokinetics of antibiotics such as levofloxacin exhibits large interindividual differences, questioning the value fixed dose regimens and warranting individual dosing based on therapeutic drug monitoring. Here, in a proof principal study, it is shown that can be detected human urine samples by employing lab-on-a-chip surface enhanced Raman spectroscopy (LoC-SERS). First, artificial used matrix order to get insights into influence different parameters complexity, aggregation time,...
The emergence of antibacterial resistance and the development new drugs lead to a continuous change guidelines for medical treatments. Hence, analytical tools are required detection in biological fluids. In this study, first surface enhanced Raman scattering (SERS) nitroxoline (NTX) purified water spiked human urine samples is reported. Insights concerning nature molecule-metal interaction its influence on overall SERS signal provided. Furthermore, three randomly collected originating from...
Pyocyanin (PYO) is a metabolite specific for Pseudomonas aeruginosa. In the case of immunocompromised patients, it currently considered biomarker life-threating infections. frame this study shown, that PYO can be detected in aqueous solution by employing surface-enhanced Raman spectroscopy (SERS) combined with microfluidic platform. The achieved limit detection 0.5 μM. This ~2 orders magnitude below concentration found clinical samples. Furthermore, as proof principle, SERS saliva three...
Methotrexate (MTX), an antifolate antibiotic, is detected using a lab-on-a-chip device<italic>via</italic>surface enhanced Raman spectroscopy (LOC-SERS) in the therapeutic range of 10 μm to 0.1 μm.
This paper presents a multi-channel frequency-modulated continuous-wave (FMCW) radar sensor operating in the frequency range from 91 to 97 GHz. The millimeter-wave utilizes an SiGe chipset comprising single signal-generation chip and multiple monostatic transceiver (TRX) chips, which are based on 200-GHz f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> HBT technology. front end is built RF soft substrate chip-on-board technology employs...
The determination of the absorption behavior levofloxacin (levaquin) on surface silver nanoparticles and its in aqueous solution by droplet based microfluidics combined with enhanced Raman spectroscopy.
Superstructures of gold nanospheres offer augmented surface-enhanced Raman scattering (SERS) activities beyond the limits their individual building blocks. However, for application as reliable and quantitative colloidal SERS probes, some key aspects need to be considered combine efficiency robustness with respect hotspot excitation, analyte adsorption, signal stability, stability. For this purpose, we studied core/satellite superstructures spherical cores a simple optically isotropic model...
This paper presents four signal-generation chips that comprise a fundamental-wave voltage-controlled oscillator (VCO), an output buffer, and divide-by-32 prescaler. The VCOs with contiguous tuning ranges cover almost the full waveguide band from 110 to 170GHz (D-band). fastest VCO operates at up 181GHz in combination run on 1.8V, draw ~35 mA, achieve single-sideband phase noise ranging -92 -82 dBc/Hz 1MHz offset frequency. Power consumption of high-speed frequency divider first prescaler...
The presence of biomarkers characteristic for Alzheimer's disease in the retina is a controversial topic. Raman spectroscopy offers information on biochemical composition tissues. Thus, it could give valuable insight into diagnostic value retinal analysis. Within present study, retinas double transgenic mouse model, that expresses chimeric mouse/human amyloid precursor protein and mutant form human presenilin 1, corresponding control group were subjected to ex vivo imaging. data recorded...
In many applications the precise distance between different units has to be measured. The proposed measurement system operates with frequency modulated continuous wave (FMCW) radar sensors for in a cooperative but unsynchronized way. Due missing synchronization data transfer is performed by means of hardware. On other hand, this principle could easily implemented communication systems. A prototype 5.8-GHz ISM band been built, and results up about 780 meters accuracies few centimeters are...
Retinal diseases, such as age-related macular degeneration, are leading causes of vision impairment, increasing in incidence worldwide due to an aging society. If diagnosed early, most cases could be prevented. In contrast standard ophthalmic diagnostic tools, Raman spectroscopy can provide a comprehensive overview the biochemical composition retina label-free manner. A proof concept study applicability nonresonant for retinal investigations is presented. imaging provides valuable insights...
Abstract Molecular specific and highly sensitive detection is the driving force of surface-enhanced Raman spectroscopy (SERS) community. The technique opens window to undisturbed monitoring cellular processes in situ or quantification small molecular species that do not deliver signals. smart design SERS nanosensors makes it possible indirectly but specifically detect, e.g. reactive oxygen species, carbon monoxide potentially toxic metal ions. Detection schemes evolved over years from simple...
Raman spectroscopy probes the biochemical composition of samples in a non-destructive, non-invasive and label-free fashion yielding specific information on molecular level. Nevertheless, effect is very weak. The detection all inelastically scattered photons with highest efficiency therefore crucial as well identification noise sources present system. Here we provide study for performance comparison assessment different spectrometers confocal biosensor applications. A low-cost, home-built...
Commercially available HD-DVD templates have been used to theoretically predict the occurrence of surface plasmons supermodes which improve detection enhanced Raman signals.
This paper reflects on design aspects for multi-channel frequency-continuous (FMCW) wave radar frontends from conception to application board. In the 79-GHz domain, applications are recapitulated, and in 94-GHz a broadband transceiver is presented along with voltage-controlled oscillator (VCO) that covers tuning range of 12 GHz. The functionality chipset was verified by means four-channel multiple-input multiple-output (MIMO) prototype. Finally, highly integrated 120-GHz on-chip signal...