A5008501753- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Spectroscopy and Laser Applications
- Advanced Chemical Sensor Technologies
- Atmospheric and Environmental Gas Dynamics
- Antibiotics Pharmacokinetics and Efficacy
- Malaria Research and Control
- Protein Interaction Studies and Fluorescence Analysis
- Microfluidic and Capillary Electrophoresis Applications
- Soil Carbon and Nitrogen Dynamics
- Photonic Crystal and Fiber Optics
- Molecular spectroscopy and chirality
- Peatlands and Wetlands Ecology
- Atmospheric chemistry and aerosols
- Plant Water Relations and Carbon Dynamics
- Microbial Community Ecology and Physiology
- Mass Spectrometry Techniques and Applications
- Advanced Fiber Optic Sensors
- Analytical Chemistry and Chromatography
- Plant responses to elevated CO2
- Analytical Chemistry and Sensors
- Isotope Analysis in Ecology
- Water Quality Monitoring and Analysis
- Planetary Science and Exploration
- Optical Network Technologies
Merck (Germany)
2021-2024
Leibniz Institute of Photonic Technology
2015-2024
Technical University of Darmstadt
2021-2024
Friedrich Schiller University Jena
2015-2024
Helmholtz Institute Jena
2006-2021
Institute of Physical Chemistry
2015-2017
Institute of Physical Chemistry
2016
InfectoGnostics Research Campus Jena
2015
Imperial College London
2010
Martin Luther University Halle-Wittenberg
2006-2007
Versatile multigas analysis bears high potential for environmental sensing of climate relevant gases and noninvasive early stage diagnosis disease states in human breath. In this contribution, a fiber-enhanced Raman spectroscopic (FERS) suite atmospheric is presented, which allowed reliable quantification CH4, CO2, N2O alongside N2 O2 with just one single measurement. A highly improved analytical sensitivity was achieved, down to sub-parts per million limit detection dynamic range 6 orders...
Breath gas analysis is a novel powerful technique for noninvasive, early-stage diagnosis of metabolic disorders or diseases. Molecular hydrogen and methane are biomarkers colonic fermentation, because malabsorption oligosaccharides (e.g., lactose fructose) small intestinal bacterial overgrowth. Recently, the presence these gases in exhaled breath was also correlated with obesity. Here, we report on highly selective sensitive detection molecular within complex mixture (consisting H2, CH4, N2,...
Karstic caves represent one of the most important subterranean carbon storages on Earth and provide windows into subsurface. The recent discovery Herrenberg Cave, Germany, gave us opportunity to investigate diversity potential role bacteria in carbonate mineral formation. Calcite was only observed by Raman spectroscopy precipitate as stalactites from seepage water. Bacterial cells were found surface interior confocal laser scanning microscopy. Proteobacteria dominated microbial communities...
Broadband fiber enhanced Raman spectroscopy (FERS) in aqueous media is introduced elaborated hollow-core photonic crystal fibers. The high requirements on the filigree structure were thoroughly analyzed. A preparation technique was developed for precise selective filling of such high-performance sensor step-index light guidance solutions achieved first time fibers across whole visible and NIR spectral range. Thus, strong signal enhancements could be demonstrated with various excitation...
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRaman Spectroscopy and Imaging in BioanalyticsDana Cialla-MayDana Cialla-MayLeibniz-Institute of Photonic Technology, Member the Leibniz Research Alliance − Health Technologies, Albert-Einstein-Str. 9, 07745 Jena, GermanyInstitute Physical Chemistry Abbe Center Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 GermanyInfectoGnostics Campus Applied Research, Philosophenweg 7, GermanyMore by Dana Cialla-MayView Biography, Christoph...
Methods to probe the molecular structure of living cells are paramount importance in understanding drug interactions and environmental influences these complex dynamical systems. The coupling an acoustic levitation device with a micro-Raman spectrometer provides direct cellular chemistry containerless environment minimizing signal attenuation eliminating affects adhesion walls interfaces. We show that Raman spectroscopic (RALS) approach can be used monitor heme dynamics levitated 5 µL...
Fiber enhanced UV resonance Raman spectroscopy is introduced for chemical selective and ultrasensitive analysis of drugs in aqueous media. The application hollow-core optical fibers provides a miniaturized sample container analyte flow efficient light-guiding, thus leading to strong light–analyte interactions highly improved analytical sensitivity with the lowest demand. signals important antimalaria chloroquine mefloquine were strongly utilizing deep electronic resonant excitation augmented...
Guiding light inside the hollow cores of microstructured optical fibers is a major research field within fiber optics. However, most current reveal limited spectral operation ranges between mid-visible and infrared rely on complicated microstructures. Here we report new type hollow-core fiber, showing for first time distinct transmission windows deep ultraviolet near infrared. The guiding in single mode, operates by central core mode being anti-resonant to adjacent modes, leading novel...
We present an approach how to combine large-mode field diameters with effective single-mode guidance in a hollow-core antiresonant optical fiber. demonstrate experimentally and simulations that is achieved simplified fiber design core diameter of 30 μm by shifting the indices first cladding modes close those higher order modes. Our shows low loss propagation operation from near infrared deep ultraviolet wavelengths down 270 nm on level approximately 3 dB/m.
Despite its potentially high relevance for nitrate removal in freshwater environments limited organic carbon, chemolithoautotrophic denitrification has rarely been studied oligotrophic groundwater. Using thiosulfate and H2 as electron donors, we established a enrichment culture from groundwater of carbonate-rock aquifer to get more insight into the metabolic repertoire, substrate turnover, transcriptional activity subsurface denitrifying consortia. The enriched consortium was dominated by...
Stable isotopes are used in ecology to track and disentangle different processes pathways. Especially for studies focused on the gas exchange of plants, sensing techniques that offer oxygen (O2) carbon dioxide (CO2) sensitivity with isotopic discrimination highly sought after. Addressing this challenge, fiber-enhanced Raman spectroscopy is introduced as a fast optical technique directly combining 13CO2 12CO2 well 18O2 16O2 measurements one instrument. We demonstrate how new type hollow-core...
Power-to-gas is a heavily discussed option to store surplus electricity from renewable sources. Part of the generated hydrogen could be fed into gas grid and lead fluctuations in composition fuel gas. Consequently, both operators transmission networks end users would need frequently monitor ensure safety as well optimal stable operation. Currently, chromatography-based analysis methods are state art. However, these have several downsides for time-resolved distributed application Raman...
Abstract Alloyed lead‐free double perovskites display intense photoluminescence, are environmentally friendly, and their devices show long‐term operation. Thanks to these properties, which make them excellent warm white‐emitting materials, they have recently received great attention in lighting applications. An important factor tune the optical properties of alloyed is presence self‐trapped excitons. Here, it demonstrated that perovskites, strong electron–phonon coupling plays a crucial role...
Malaria is a severe disease caused by cytozoic parasites of the genus Plasmodium, which infiltrate and infect red blood cells. Several drugs have been developed to combat devastating effects malaria. Antimalarials based on quinolines inhibit crystallization hematin into hemozoin within parasite, ultimately leading its demise. Despite frequent use these agents, there are unanswered questions about their mechanisms action. In present study, quinoline chloroquine interaction with target...
Cavity-enhanced Raman multigas spectrometry is introduced as a versatile technique for monitoring of 13CO2 isotope labeling experiments, while simultaneously quantifying the fluxes O2 and other relevant gases across wide range concentrations. The analysis was performed in closed cycle; no gas consumed, composition not altered by measurement. Isotope plant metabolites via photosynthetic uptake enables investigation resource flows plants now an important tool ecophysiological studies. In this...
Fiber enhanced resonance Raman spectroscopy (FERS) is introduced for chemically selective and ultrasensitive analysis of the biomolecules hematin, hemoglobin, biliverdin, bilirubin. The abilities analyzing whole intact, oxygenated erythrocytes are proven, demonstrating potential diagnosis red blood cell related diseases, such as different types anemia hemolytic disorders. optical fiber enables an efficient light-guiding within a miniaturized sample volume only few micro-liters provides...
Cavity-enhanced Raman spectroscopy is a powerful tool for online detection of multiple gases during the process biogas production.
A single FERS sensor for simultaneous oxygen (O<sub>2</sub>), carbon dioxide (CO<sub>2</sub>), ammonia (NH<sub>3</sub>), and ethylene (C<sub>2</sub>H<sub>4</sub>) monitoring is presented applications in postharvest fruit management.