A5012269408- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Pregnancy-related medical research
- Maternal and fetal healthcare
- Preterm Birth and Chorioamnionitis
- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Maternal and Perinatal Health Interventions
- Gestational Diabetes Research and Management
- Petroleum Processing and Analysis
- Pregnancy and Medication Impact
- Enhanced Oil Recovery Techniques
- MicroRNA in disease regulation
- Renal and related cancers
- Neurological Complications and Syndromes
- Hydrocarbon exploration and reservoir analysis
- Anesthesia and Neurotoxicity Research
- Pelvic floor disorders treatments
- Ion Transport and Channel Regulation
- Cardiovascular Issues in Pregnancy
- Prenatal Screening and Diagnostics
- Electrolyte and hormonal disorders
- Cancer-related molecular mechanisms research
- Congenital Diaphragmatic Hernia Studies
- COVID-19 Impact on Reproduction
PLA Army Service Academy
2016-2025
Guangzhou Medical University
2016-2025
South China University of Technology
2021-2024
South China Normal University
2024
Guangzhou Women and Children Medical Center
2011-2023
First Affiliated Hospital of Jinan University
2020-2023
Guangdong Province Women and Children Hospital
2023
Southwest Petroleum University
2021-2022
Chinese People's Liberation Army
2018
China University of Petroleum, Beijing
2012-2013
BACKGROUND: This trial aimed to assess the efficacy, acceptability, and safety of a first-trimester screen-and-prevent strategy for preterm preeclampsia in Asia. METHODS: Between August 1, 2019, February 28, 2022, this multicenter stepped wedge cluster randomized included maternity/diagnostic units from 10 regions The started with period where all recruiting centers provided routine antenatal care without study-related intervention. At regular 6-week intervals, one was transit...
Abstract Background The transition of the myometrium from a quiescent to contractile state during labour is known involve inflammation, which characterized by infiltration immune cells and secretion cytokines. However, specific cellular mechanisms underlying inflammation in human parturition are not yet fully understood. Methods Through analysis transcriptomics, proteomics, cytokine arrays, was revealed. By performing single‐cell RNA sequencing (scRNA‐seq) spatiotemporal transcriptomic (ST)...
In this study, the gas–water–hydrate–sand four-phase flow characteristics were simulated using Eulerian model and a user-defined function for hydrate particle diameter in fluent. The results indicate that (1) straight pipe section, hydrates concentrated middle lower regions, while sand particles settled at bottom. bend mainly on outer side, inner side. (2) increasing velocity reduced concentration center, promoting more homogeneous cross-sectional distribution due to enhanced turbulent...
Abstract Background Placenta accreta spectrum disorders (PAS) are a severe complication characterized by abnormal trophoblast invasion into the myometrium. The underlying mechanisms of PAS involve complex interplay various cell types and molecular pathways. Despite its significance, both characteristics intricate this condition remain poorly understood. Methods Spatial transcriptomics (ST) single-cell RNA sequencing (scRNA-seq), were performed on tissue samples from four patients, including...
Objective Eclampsia is a poorly understood but potentially fatal complication of pregnancy. Research to date on this disorder has been hampered by the lack suitable animal model. To correct deficiency, report describes generation rat eclampsia-like model using pentylenetetrazol (PTZ) in previously established preeclampsia Method Rats were administered lipopolysaccharide (1.0 µg/kg) tail vein injection gestational day 14 establish (PE). PE and control rats (non-pregnant, NP; normal-pregnant,...
During labor, a variety of coordinated physiological and biochemical events cause the myometrium to transition from quiescent contractile state; molecular mechanisms responsible for this transition, however, remain unclear. To better understand at level, global transcriptome proteome human myometrial samples in labor those not were investigated through RNA sequencing (RNA-seq) quantitative liquid chromatography–tandem mass spectrometry (LC-MS/MS) via data-independent acquisition (DIA)...
Wax deposition modeling is complicated under oil/gas two‐phase pipe flow and therefore remains poorly understood. One‐dimensional empirical heat mass transfer correlations are unreliably for in stratified flow, due to non‐uniform deposit across the circumference. A mathematical model has been developed predict thickness wax fraction of using a unidirectional analysis non‐isothermal hydrodynamics heat/mass transfer. The predictions found compare satisfactorily with experimental data three...
To the Editor: Spontaneous preterm labor (PTL) causes infant morbidity and mortality. Regular uterine contractions were common characteristics in spontaneous at term or PTL. Thus, effective decrease suppression of myometrial contraction could prevent delivery. We discovered that microRNA-206 (miR-206) was a myometrium contraction-associated miRNA based on transcriptome data human laboring indicated miR-206 suppressed contractility by targeting junction protein alpha 1 (GJA1) would be new...
Obesity has been linked to systemic inflammation in population studies.To examine the associations of prepregnancy body mass index (pBMI) and total gestational weight gain (tGWG) with maternal prepartum low-grade (LGI) clinically significant (CSI) defined by serum C-reactive protein (CRP) concentration.Five thousand four hundred seventy-six Chinese women uncomplicated pregnancies recorded data on pBMI were included this study. Blood samples drawn before delivery for high-sensitivity CRP...