A5060931265- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Luminescence and Fluorescent Materials
- Endodontics and Root Canal Treatments
- Carbon and Quantum Dots Applications
- Cancer, Hypoxia, and Metabolism
- Protein purification and stability
- Inflammatory mediators and NSAID effects
- Glycosylation and Glycoproteins Research
- Retinoids in leukemia and cellular processes
- Plant Gene Expression Analysis
- Cancer Mechanisms and Therapy
- Nanocluster Synthesis and Applications
- Photosynthetic Processes and Mechanisms
- Selenium in Biological Systems
- Estrogen and related hormone effects
- Tissue Engineering and Regenerative Medicine
- Peroxisome Proliferator-Activated Receptors
- Photodynamic Therapy Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Monoclonal and Polyclonal Antibodies Research
- Ferroptosis and cancer prognosis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Graphene and Nanomaterials Applications
- Biological Stains and Phytochemicals
Hangzhou Normal University
2023
Stomatology Hospital
2014-2022
Sun Yat-sen University
2014-2021
University of Cambridge
2020-2021
Wuhan University
2018-2020
Hubei Provincial Center for Disease Control and Prevention
2018-2020
City University of Hong Kong, Shenzhen Research Institute
2018-2020
Zhejiang University
2020
State Key Laboratory of Virology
2018-2020
Hospital of Stomatology, Sun Yat-sen University
2014
Novel biocompatible NIR-II aggregation-induced emission dots are facilely assembled and used for biomedical fluorescence imaging.
The development of novel biodegradable and nontoxic fluorophores that integrate diagnosis therapy for effective cancer treatment has obtained tremendous attention in the past decades. In this report, water-soluble biocompatible small-molecule near-infrared II (NIR-II) fluorescent dye H2a-4T complexed with fetal bovine serum (FBS) Cetuximab proteins excellent optical properties targeting ability is prepared. High spatial temporal resolution imaging hind limb vasculature lymphatic system...
Traditional luminescent materials including fluorescent probes suffer from notorious aggregation-caused quenching (ACQ) in aqueous solutions. Although several approaches such as the aggregation-induced emission (AIE) effect have been developed, it remains a significant challenge to identify an effective and efficient strategy resolve this issue. Herein, quaternary ammonium salts Q8PBn Q8PNap novel class of bright near infrared window II (NIR-II, 1,000 - 1,700 nm) were designed synthesized,...
Increasing biotic and abiotic stresses are seriously impeding the growth yield of staple crops threatening global food security. As one largest classes regulators in vascular plants, WRKY transcription factors play critical roles governing flavonoid biosynthesis during stress responses. By binding major W-box cis-elements (TGACCA/T) target promoters, WRKYs modulate diverse signaling pathways. In this review, we optimized existing phylogenetic trees by incorporating additional plant species...
It has been suggested that retinoic acid (RA) a potential role in the prevention of atherosclerotic CVD. In present study, we used J774A.1 cell lines and primary peritoneal macrophages to investigate protective effects RA on foam formation atherogenesis apoE-deficient (apoE − / ) mice. A total twenty male apoE mice ( n 10 animals per group), aged 8 weeks, were fed high-fat diet (HFD) treated with vehicle or 9- cis -RA for weeks. The plaque area aortic sinus group was 40·7 % less than control...
Graphene oxide quantum dots (GOQDs) are a carbon nanomaterial with broad potential for application in the field of biomedicine. Stem cells from human exfoliated deciduous teeth (SHEDs) play an important role tissue engineering and regenerative medicine. This study investigated effects GOQDs on SHED osteogenic differentiation. were synthesized; then, proliferation SHEDs incubated at different concentrations was evaluated; live observed. We observed that emitted green fluorescence absence...
The expansion of structural databases and the increase in computing power are enabling approaches for antibody discovery based on computational design. It has already been shown that it is possible to use this approach generate antibodies specific epitopes challenging targets. Here we describe an application procedure maturation through design mutational variants increased potency. We illustrate case a single-domain targeting epitope N-terminal region Aβ42, peptide whose aggregation closely...
Correction for ‘Novel near-infrared II aggregation-induced emission dots <italic>in vivo</italic> bioimaging’ by Jiacheng Lin <italic>et al.</italic>, <italic>Chem. Sci.</italic>, 2019, <bold>10</bold>, 1219–1226.
Objective To investigate the effect of heparin on osteoprotegerin (OPG) content and cells apoptosis in rat cervical loop zone lower incisors.Methods Twenty-four Sprague-Dawley (SD) rats aged 4 weeks were divided into two groups randomly.The experimental group was subcutaneously injected with at abdomen per day by dose 1 U/g,and control normal sodium (NS) same volume.All sacrificed after weeks,their right femurs obtained for measurement bone mineral density (BMD),and mandibles...
Abstract Objective to investigate preoperative factors that may influence the root development of regenerative endodontic procedures (REPs). Patients and Methods A total 116 teeth in 110 patients treated with REPs Paediatric Dentistry Department Endodontics from 2013 2017 were included this study. Factors including aetiology, age, diagnosis initial morphology collected retrospectively, associations between these after analysed by Fisher's exact test multivariate logistic regression model....
Abstract Background Regenerative endodontic procedures (REPs) has achieved clinical success on the immature permanent teeth with pulp necrosis, and can promote root development. However, preoperative factors their effects development of REPs have not been definitely concluded. The aim this study was to investigate that may influence REPs. Methods A total 116 in 110 patients treated Paediatric Dentistry Department Endodontics from 2013 2017 were included study. Factors including aetiology,...