A5027652363- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticle-Based Drug Delivery
- Magnetic Properties and Synthesis of Ferrites
- Iron oxide chemistry and applications
- Geomagnetism and Paleomagnetism Studies
- Nanoplatforms for cancer theranostics
- Minerals Flotation and Separation Techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- RNA Interference and Gene Delivery
- Magnetic properties of thin films
- CRISPR and Genetic Engineering
- Microfluidic and Bio-sensing Technologies
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- HIV Research and Treatment
- Virus-based gene therapy research
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
- Mosquito-borne diseases and control
- Polymer composites and self-healing
- Brain Tumor Detection and Classification
- 3D Printing in Biomedical Research
- Photoreceptor and optogenetics research
- Plasmonic and Surface Plasmon Research
- Ultrasound and Hyperthermia Applications
University of Houston - Victoria
2022-2025
Kennesaw State University
2025
Florida International University
2016-2022
Institute of Neuroimmunology of the Slovak Academy of Sciences
2016-2020
Nanomed (Brazil)
2017-2020
University of Washington
2012-2015
Seattle University
2015
Kyoto University
2012-2014
Yokohama National University
2009-2012
National University of Singapore
2009
Abstract CRISPR-Cas9/gRNA exhibits therapeutic efficacy against latent human immunodeficiency virus (HIV) genome but the delivery of this cargo to brain remains as a challenge. In research, for first time, we demonstrated magnetically guided non-invasive nano-formulation (NF), composed Cas9/gRNA bound with magneto-electric nanoparticles (MENPs), across blood-brain barrier (BBB) inhibit HIV-1 infection in microglial (hμglia)/HIV (HC69) cells. An optimized ac-magnetic field 60 Oe was applied...
Engineered terahertz (THz) plasmonic metamaterials have emerged as promising platforms for quick infection diagnosis, cost-effective and real-time pharmacology applications owing to their non-destructive harmless interaction with biological tissues in both vivo vitro assays. As a recent member of THz family, toroidal been demonstrated be supporting high-quality sharp resonance modes. Here we introduce metasensor based on surface consisting metamolecules that support ultra-narrow resonances...
The first study of Magnetic Particle Imaging (MPI) for tomographic imaging cancer targeted iron oxide nanoparticles.
Monodisperse lactoferrin conjugated iron oxide nanoparticles were synthesized and evaluated for<italic>in vitro</italic>glioma imaging using Magnetic Particle Imaging (MPI).
Lateral flow assay has been extensively used for at-home testing and point-of-care diagnostics in rural areas. Despite its advantages as convenient low-cost testing, it suffers from poor quantification capacity where only yes/no or positive/negative are achieved. In this study, machine learning deep models were developed to quantify the analyte load smartphone-captured images of lateral test. The comparative analysis identified that random forest convolutional neural network (CNN) performed...
Magnetic and AC magnetically induced heating characteristics of Fe3O4 nanoparticles (IONs) with different mean diameters, d, systematically controlled from 4.2 to 22.5 nm were investigated explore the physical relationship between magnetic phase specific loss power (SLP) for hyperthermia agent applications. It was experimentally confirmed that IONs had three phases correspondingly SLP depending on particle sizes. Furthermore, it demonstrated pure superparamagnetic (d &lt; 9.8 nm) showed...
Magneto-plasmonic nanoparticles are one of the emerging multi-functional materials in field nanomedicine. Their potential for targeting and multi-modal imaging is highly attractive. In this study, magnetic core/gold shell (MNP@Au) magneto-plasmonic were synthesized by citrate reduction Au ions on nanoparticle seeds. Hydrodynamic size optical properties with variation reducing agent concentrations evaluated. The exhibited superparamagnetic properties, their contributed to...
Magneto-plasmonic liposomes were developed for image-guided drug delivery, and showed multimodal imaging, enhanced BBB transmigration, reduction of viral replication.
Abstract Smart multifunctional nanoparticles with magnetic and plasmonic properties assembled on a single nanoplatform are promising for various biomedical applications. Owing to their expanding imaging therapeutic capabilities in response external stimuli, they have been explored on-demand drug delivery, image-guided simultaneous diagnostic (i.e. theranostic) In this study, we engineered unique morphology consisting of superparamagnetic iron oxide core star-shaped shell high-aspect-ratio...
Magnetic particle dipole interaction was revealed as a crucial physical parameter to be considered in optimizing the ac magnetically induced heating characteristics of magnetic nanoparticles. The temperature soft MFe2O4 (M=Mg,Ni) nanoparticles remarkably increased from 17.6 94.7 °C (MgFe2O4) and 13.1 103.1 (NiFe2O4) by increasing energy at fixed field 140 Oe frequency 110 kHz. increase “magnetic hysteresis loss” that resulted main reason for significant improvement characteristics.
Multifunctional nanoparticles with a magnetic core and gold shell structures are emerging multi-modal imaging probes for disease diagnosis, image-guided therapy, theranostic applications. Owing to their multi-functional plasmonic properties, these can be used as contrast agents in multiple complementary modalities. Magnetic particle (MPI) is new pre-clinical system that enables real-time high sensitivity spatial resolution by detecting the dynamic responses of nanoparticle tracers. In this...
The emerging field of theranostics for advanced healthcare has raised the demand effective and safe delivery systems consisting therapeutics diagnostics agents in a single monarchy. This requires development multi-functional bio-polymeric efficient image-guided therapeutics. study reports size-controlled (micro-to-nano) auto-fluorescent biopolymeric hydrogel particles chitosan hydroxyethyl cellulose (HEC) synthesized using water-in-oil emulsion polymerization technique. Sustainable resource...
Magnetic nanoparticles can potentially be used in drug delivery systems and for hyperthermia therapy. The applicability of <TEX>$Fe_3O_4$</TEX>, <TEX>$CoFe_2O_4$</TEX>, <TEX>$MgFe_2O_4$</TEX>, <TEX>$NiFe_2O_4$</TEX> the same was studied by evaluating their magnetization, thermal efficiency, biocompatibility. <TEX>$Fe_3O_4$</TEX> <TEX>$CoFe_2O_4$</TEX> exhibited large magnetization. induction heating. <TEX>$MgFe_2O_4$</TEX> low magnetization compared to other nanoparticles. were found...
Magnetic nanoparticles are promising materials for hyperthermia treatment. The temperature rise under ac magnetic field, cytotoxicity, and in vitro effect of Fe 3 O 4 coated with Pluronic f‐127 were evaluated this paper. Pluronic‐coated exhibited no cytotoxic on HeLa cells. optimal field was 16 kA/m (200 Oe) at the strength 210 kHz. Appropriate significantly reduced viability cells induced apoptosis.
Abstract HIV and substance abuse plays an important role in infection disease progression. Further, the presence of persistent viral CNS reservoirs makes complete eradication difficult. Thus, neutralizing drug effect on HIV-1 infectivity elimination latently infected cells is a priority. The development multi-component [antiretroviral drugs (ARV), latency reactivating agents (LRA) antagonist (AT)] sustained release nanoformulation targeting can overcome issues cure will help improving...