A5030996717- Spine and Intervertebral Disc Pathology
- Spinal Cord Injury Research
- Musculoskeletal pain and rehabilitation
- Angiogenesis and VEGF in Cancer
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Coronary Interventions and Diagnostics
- Bone fractures and treatments
- Hip and Femur Fractures
- Trauma and Emergency Care Studies
- TGF-β signaling in diseases
- Spinal Fractures and Fixation Techniques
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Cerebrovascular and Carotid Artery Diseases
- Hemostasis and retained surgical items
- Intraoperative Neuromonitoring and Anesthetic Effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Connective Tissue Growth Factor Research
- Spinal Dysraphism and Malformations
- Kruppel-like factors research
- Mycobacterium research and diagnosis
- Nerve Injury and Rehabilitation
- Breast Cancer Treatment Studies
- Childhood Cancer Survivors' Quality of Life
Indian Spinal Injuries Centre
2018-2023
Cadila Healthcare (India)
2016-2021
Midas Multispeciality Hospital
2020-2021
Smt. N.H.L. Municipal Medical College
2015-2018
Wisconsin Institutes for Discovery
2012-2017
Maharshi Dayanand University
2015
University of Wisconsin–Madison
2012-2015
Shirley Ryan AbilityLab
2014
Institute for Medical Research
2012-2013
Highland Community College - Illinois
2012
Since the time of its inception, 3D printing has not only fascinated researchers but also health professionals. Though process is exciting, it involves meticulous coordination and selection to achieve a desirable product. This review article discusses about history evolution 3 D printers, their current application future trends. Emphasis been laid recognize best suitable product ways prevent misuse.
Abstract Low back pain is often the direct result of degeneration intervertebral disc. A wide range therapeutics including anti-catabolic, pro-anabolic factors and chemo-attractants that can stimulate resident cells recruit endogenous progenitors are under consideration. The avascular nature dense matrix this tissue make it challenging for systemically administered drugs to reach their target inside nucleus pulposus (NP), central gelatinous region disc (IVD). Therefore, local intra-discal...
Background— Three major processes, constrictive vessel remodeling, intimal hyperplasia (IH), and retarded re-endothelialization, contribute to restenosis after vascular reconstructions. Clinically used drugs inhibit IH but delay re-endothelialization also cause remodeling. Here we have examined halofuginone, an herbal derivative, for its beneficial effects on remodeling differential inhibition of versus re-endothelialization. Methods Results— Two weeks perivascular application...
Abstract To date, there is no periadventitial drug delivery method available in the clinic to prevent restenotic failure of open vascular reconstructions. Resveratrol a promising anti-restenotic natural but subject low bioavailability when systemically administered. In order reconcile these two prominent issues, we tested effects resveratrol on all three major pro-restenotic pathologies including intimal hyperplasia (IH), endothelium impairment, and vessel shrinkage. rat carotid injury...
Intimal hyperplasia is the cause of recurrent occlusive vascular disease (restenosis). Drugs currently used to treat restenosis effectively inhibit smooth muscle cell (SMC) proliferation, but also growth protective luminal endothelial (EC) lining, leading thrombosis. To identify compounds that selectively SMC versus EC we have developed a high-throughput screening (HTS) format using human cells and employed this screen multiple compound collection (NIH Clinical Collection). We an automated,...
Nonrandomized, prospective, and case-controlled study.To evaluate the efficacy cost-effectiveness of topically applied tranexamic acid (TXA) during different phases spine surgery.Perioperative blood loss is leading cause postoperative anemia associated with prolonged stays in hospital long recovery times. The direct indirect costs involved pose a significant economic challenge developing countries. There no consensus for topical use surgery.Patients requiring single-level TLIF were divided...
Background: The inclusion of people living with spinal cord injury (SCI) in research has allowed for an informed understanding priorities recovery which bowel dysfunction and bladder have been continuously identified. Research also demonstrated the global disparities SCI outcomes particularly when comparing high- low-income countries. Currently, there is a lack direct comparison between countries assessing outcomes. Objectives: This exploratory study to better understand amongst individuals...
Introduction: In the recent era of trauma, about one million people get seriously injured annually. Majority them suffer from lower limb injuries. Due to lack trauma registry in India, prediction models are not much effective. The aim our study was derive basic epidemiological parameters for injuries which can be used develop better reduce morbidities and mortalities. Methods: We conducted an observational on isolated without any musculoskeletal disorder at a tertiary care institution...
Background: The socioeconomic impact after cervical spine surgery in patients with injury have not been reviewed. aim of this study was to analyze the clinico-radiological results and even radiologically successful surgery. Materials Methods: One hundred thirteen surviving individuals (out 166) were included retrospective from hospital record who belonged lower group as per Kuppuswamy scale. All had undergone (anterior or posterior) for spinal 2007 2014. sustained either purely traumatic...
The elevated I-maze is a modification of the plus-maze model anxiety in mice. design comprises straight wooden passage, resembling English letter "I," divided equally into three areas; two enclosed areas (close arms) at both ends "maze" and an open area center areas. completely avoids central platform plus-maze, removing any ambiguity time spent on allowing uninterrupted animal exploration. In this model, diazepam (1 mg/kg) gabapentin (10 significantly increased percentage (%TO) number...
Background: Patient satisfaction at spine surgery centers is a matter of concern. In specialized surgeries like spine, the patient not merely because surgical outcomes but also empathy doctor, rehabilitation programs and friendliness hospital.
 Aims Objectives: This study aims to investigate prognosis level patients/relatives operated with spinal surgery. shall only help hospitals know ways improve outcome methods provide better services.
 Material methods: The was conducted by...
Pheohyphomycosis is an uncommon infection and its association in spondylodiscitis has not yet been reported. The purpose of this case report to describe a rare Pheohyphomycotic methods diagnose manage the patient with less invasive techniques. A 29-year-old male presented outpatient department complaints gradually increasing low back pain bilateral lower limbs radicular since one half years. He had associated fever, weight loss, voice changes, dry, scaly, erythematous skin elevated ESR....
Introduction None of study reviewed on socio-economic impact after cervical spine surgery in patients with injury or myelopathy. Aim was to clinico-radiological results and even radiologically successful surgery. Methods After board approval, 104 participants (56 traumatic, 48 myelopathy) were included. All operated at a single institute between 2007 2014 anterior approach. Patients who expired other pathology excluded, as aim aspect. Nurick scale used assess the degree loss function...
Study Design Retrospective study. Purpose Missing cottonoids during and after spinal surgery is a persistent problem account for the most commonly retained surgical instruments (RSIs) noticed final cottonoid count. The aim of this study was to enumerate risk factors describe sequence look out misplaced provide an algorithm resolving problem. Overview Literature There are only few case reports on RSIs among various branches. data inconclusive there little evidence in literature that relates...
Low back pain is a common ailment affecting individuals all around the globe. Majority of Disability Adjusted Life Years lost amongst working population due to low pain. Though majority surgeons/physicians keep only spinal causes in mind while treating such an ailments, number other exist for pathology. This editorial aims make readers aware about non
Hip joint fracture-dislocations are rare injuries and usually result from high energy trauma. Femoral head fractures account for only 7-16% of all hip fracture-dislocations. There is always a controversy regarding optimal surgical treatment modality approach the Pipkin type IV fractures. In 60 years old individual, various reports favor primary arthroplasty as compared to open reduction internal fixation (ORIF). The posterior preferred because it provides adequate exposure acetabular...
Humility has been little understood despite being an important part of the scientific writing. Many manuscripts with good data remain unpublished due to their lack humility leading repeated rejections. This Editorial aims highlight importance humble writing and how it can be incorporated by authors in methodology.
 Key words: Research, manuscript, Humble