A5101431941- Bladder and Urothelial Cancer Treatments
- Renal and Vascular Pathologies
- Viral-associated cancers and disorders
- Sexual function and dysfunction studies
- Organ Donation and Transplantation
- Pediatric Urology and Nephrology Studies
- Renal cell carcinoma treatment
- Ureteral procedures and complications
- Urinary and Genital Oncology Studies
- Prostate Cancer Diagnosis and Treatment
- Sexuality, Behavior, and Technology
- Urological Disorders and Treatments
- Multiple and Secondary Primary Cancers
- Pain Mechanisms and Treatments
- Cytomegalovirus and herpesvirus research
- Renal Transplantation Outcomes and Treatments
- Pain Management and Placebo Effect
- Fetal and Pediatric Neurological Disorders
- Lymphoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Generative Adversarial Networks and Image Synthesis
- Radiopharmaceutical Chemistry and Applications
- Hormonal and reproductive studies
- Nephrotoxicity and Medicinal Plants
- Genetic and Kidney Cyst Diseases
Second Affiliated Hospital of Nanchang University
2024-2025
Nanchang University
2025
Beijing Friendship Hospital
2014-2024
Capital Medical University
2014-2024
Huzhou Central Hospital
2024
Huzhou University
2024
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Capital University
2014-2023
Zhejiang Chinese Medical University
2023
Xiamen University
2020
microRNAs (miRNAs) have been proposed to be key regulators of diverse biological processes such as transcriptional regulation, cell growth and tumorigenesis. Wnt signaling plays an important role in the regulation tumorigenesis cancer progression. However, little is known about whether miR-144 regulates bladder proliferation by controlling signaling. In this study, we found that expression level significantly decreased lines well clinical tissues. inhibitor blocks endogenous promotes...
Primary small cell carcinoma of the ovary is an extremely rare and highly malignant ovarian malignancy. The tissue origin this type cancer still unclear, it characterized by rapid progression a discouraging prognosis. clinical presentation lacks specificity, there are currently no effective treatment options available. Therefore, crucial to improve understanding identification disease. In paper, we present case composite with mucinous adenocarcinoma provide comprehensive review relevant literature.
Pain memory is commonly considered an underlying cause of chronic pain and also responsible for a range anxiety. Electroacupuncture (EA) has been shown to ameliorate memories exert anti-anxiety effects. Previous research indicated that GABAergic neurons and/or GABA receptors (GABARs) in the midcingulate cortex (MCC) have potential associations with However, there no known empirical specifically studied effects EA on system MCC. Here, we used cross-injection carrageenan establish rats model....
Comorbid chronic neuropathic pain and anxiety is a common disease that represents major clinical challenge. The underlying mechanisms of are not entirely understood, which limits the exploration effective treatment methods. Glutamatergic neurons in ventrolateral periaqueductal gray (vlPAG) have been implicated regulating pain, but potential roles vlPAG pain-induced investigated. Herein, whole-cell recording immunofluorescence showed excitability CamkIIα (vlPAG CamkIIα+ neurons) was decreased...
We retrospectively evaluated the clinical outcome of penile prosthesis implantation (PPI) in Chinese patients with severe erectile dysfunction (SED).
Cisplatin-based combination chemotherapy regimen is a reasonable alternative to cystectomy in advanced/metastatic bladder cancer, but acquisition of cisplatin resistance common patients with cancer. Previous studies showed that loss homeodomain-interacting protein kinase-2 (HIPK2) contributes cell proliferation and tumorigenesis. However, the role HIPK2 regulating chemoresistance cancer not fully understood. In present study, we found mRNA levels are significantly decreased...
The risk of transplant recipient infection is unknown when the preservation solution culture positive.
To compare the efficiency and safety between retroperitoneal laparoscopic nephrectomy traditional open to treat autosomal-dominant polycystic kidney disease before transplantation.
Abstract To date, there is no periadventitial drug delivery method available in the clinic to prevent restenotic failure of open vascular reconstructions. Resveratrol a promising anti-restenotic natural but subject low bioavailability when systemically administered. In order reconcile these two prominent issues, we tested effects resveratrol on all three major pro-restenotic pathologies including intimal hyperplasia (IH), endothelium impairment, and vessel shrinkage. rat carotid injury...
Due to the increasing number of DCD transplantations since 2015, transmission rabies through solid organ transplantation has become a notable problem in China and attracted attention public.
Chronic kidney disease (CKD) and end stage renal (ESRD) are not well characterized in prostate cancer patients. This study aimed to examine the clinical characteristics postsurgical outcomes of patients with or without CKD ESRD undergoing radical prostatectomy for cancer. population-based, retrospective used patient data from Nationwide Inpatient Sample, largest all-payer US inpatient care database. From 2005 2014, 136,790 male aged > 20 years diagnosed who received were included....
BackgroundIntracavernous injection (ICI) of adipose-derived stem cells (ADSCs) has been demonstrated promising for neurogenic erectile dysfunction (ED). However, due to the sponge-like structure corpus cavernosum (CC) with abundant vessels, ICI was indeed like intravenous injection. Thus, cell escaping may be a concern safety and limited therapy, but issue not clearly yet.MethodsSuspensions free ADSCs (FAs) ADSCs-based spheroids (ASs) suitable size were intracavernously injected at doses...
Novel magnetic hollow spheres based on iron oxide have been designed and synthesized <italic>via</italic> a facile cost-effective one-pot solvothermal route, successfully acted as nanocarriers for the high-performance delivery of insoluble anticancer drugs <italic>in vitro</italic>.
Few studies have systematically explored the factors influencing difficulty of hand-assisted laparoscopic living donor nephrectomy. To investigate relationship between nephrectomy and postoperative complications as well recipient, then build a model for predicting surgery. In this study, 60 patients who underwent by same surgeon from September 2022 to March 2024 were included modeling group. 20 operated on another served external validation The subjective score (1–3 points) surgical was used...
We aimed to introduce our modified hand-assisted retroperitoneoscopic living donor nephrectomy (HARPLDN) technique and define the learning curve. One hundred thirty-eight kidney donors who underwent HARPLDN by same surgeon between May 2015 March 2022 were included. A cumulative sum (CUSUM) curve analysis was performed with total operation time as study outcome. In total, mean operative 138.2 ± 32.1 min. The median warm ischemic (WIT) estimated blood loss 90 s 50 ml, respectively. for best...
The security concerns surrounding Large Language Models (LLMs) have been extensively explored, yet the safety of Multimodal (MLLMs) remains understudied. In this paper, we observe that can be easily compromised by query-relevant images, as if text query itself were malicious. To address this, introduce MM-SafetyBench, a comprehensive framework designed for conducting safety-critical evaluations MLLMs against such image-based manipulations. We compiled dataset comprising 13 scenarios,...
Long-term outcome of DAAs therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it a Chinese cohort HCV-infected recipients. Single-center and retrospective study initiating an regimen between January 2015 December 2017 conducted. Totally 26 KTX were divided into three groups, including KTX-HD Group, DAA-KTX Group KTX-DAA Group. On-treatment response defined as target not detected within 12 weeks. SVR 48, 96 HCV-RNA negativity weeks after treatment cessation,...
Background: Potent immune-suppressive therapy has been demonstrated to increase the risk of infective endocarditis (IE) in renal recipients. Reports Corynebacterium striatum ( C. ) recipients are scarce, thus limiting understanding disease. Case Presentation: We describe a case native valve caused by 35-year-old male patient. The young man with end-stage failure underwent kidney transplantation because autosomal dominant polycystic Ceftazidime was administered after surgery according routine...