A5031186695- Hypothalamic control of reproductive hormones
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Estrogen and related hormone effects
- Renal Diseases and Glomerulopathies
- Cytomegalovirus and herpesvirus research
- Reproductive System and Pregnancy
- Organ and Tissue Transplantation Research
- Nutritional Studies and Diet
- Chronic Kidney Disease and Diabetes
- Diet and metabolism studies
- Asthma and respiratory diseases
- Ovarian function and disorders
- Mycobacterium research and diagnosis
- Organ Donation and Transplantation
- Pediatric health and respiratory diseases
- Adipose Tissue and Metabolism
- Phytoestrogen effects and research
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Effects and risks of endocrine disrupting chemicals
- Pneumocystis jirovecii pneumonia detection and treatment
- Medicinal Plant Pharmacodynamics Research
- Dietary Effects on Health
Children's Hospital of Fudan University
2013-2025
Nanjing Sport Institute
2023-2025
Jiangsu University
2025
University of Science and Technology of China
2024
Weatherford College
2024
Versus Arthritis
2024
Beijing Friendship Hospital
2008-2022
Capital Medical University
2008-2022
Peking University First Hospital
2022
Peking University
2022
Mitochondrial function is crucial for hepatic lipid metabolism. Current research identifies two types of mitochondria based on their contact with droplets: peridroplet (PDM) and cytoplasmic (CM). This work aimed to investigate the alterations CM PDM in metabolic dysfunction-associated steatotic liver disease (MASLD) induced by spontaneous type-2 diabetes mellitus (T2DM) db/db mice. It was found that insulin resistance increased both number size droplets enhancing accumulation free fatty...
Childhood obesity frequently persists into adulthood and is associated with an increased risk earlier onset of cardiovascular disease in later life. Behavioral change strategies have been proposed as the first-line weight management approach for children adolescents obesity. Nonpharmacological interventions, such traditional Chinese medicine (TCM) auricular acupressure treatment intermittent low-carbohydrate diet (ILCD), are increasingly being investigated young obese population. However,...
Inflammatory bowel disease (IBD) has become a global healthcare issue, with its incidence continuing to rise, but currently there is no complete cure. Xylitol widely used sweetener in various foods and beverages, limited research on the effects of xylitol IBD symptoms. Study effect oral improving intestinal inflammation damage mice, further explore mechanism alleviating symptoms using microbiota non-targeted metabolomics techniques. An mouse model was induced sodium dextran sulfate (DSS)....
<sec> <title>UNSTRUCTURED</title> Childhood obesity frequently persists into adulthood and is associated with an increased risk earlier onset of cardiovascular disease in later life. Behavioral change strategies have been proposed as the first-line weight management approach for children adolescents obesity. Nonpharmacological interventions, such traditional Chinese medicine (TCM) auricular acupressure treatment intermittent low-carbohydrate diet (ILCD), are increasingly being investigated...
Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog gonadotropin-inhibitory hormone, implicated in inhibiting synthesis release of gonadotropin mammals. However, it unclear whether RFRP-3 participates regulating pubertal development.This study investigated functional significance regulatory mechanism hypothalamic neuropeptide puberty young female rats. On postnatal...
Abstract Neonatal exposure to bisphenol A (BPA) is hypothesized advance pubertal development. However, the effects of neonatal BPA on development has not been described. In this study, female Sprague‐Dawley rats were exposed 0.05, 0.5, 5, or 10 mg·kg −1 ·day BPA, corn oil vehicle alone from postnatal day 1 (PND1) PND10 via subcutaneous injection. We evaluated vaginal opening (DVO), ovarian morphology, serum hormone concentrations, and hypothalamic expression Gnrh1 Kiss1 in at PND35. DVO was...
Objective. To observe the effects of empirical prescriptions traditional Chinese medicine (TCM) on inflammatory mediators in pediatric asthma and to explore underlying molecular mechanism treatment asthma. Methods. A total 182 children with were randomly placed into either TCM group (n = 97) or salbutamol montelukast (SM) 85). Patients treated a series TCM, while those SM received montelukast. Both groups their respective for 12 weeks. There 35 patients 34 providing venous blood. Real-time...
Modifiable lifestyle factors are implicated as risk for neurological and psychiatric disorders, but whether these associations causal remains uncertain. We aimed to evaluate ascertain relationships between modifiable factors, disorder risk, brain structural magnetic resonance imaging (MRI) markers.
To investigate the efficacy of non-buckled vitrectomy with classical endotamponade agents in treatment primary retinal detachment (RD) complicated by inferior breaks and proliferative vitreoretinophathy (PVR).A retrospective, consecutive case series study 40 patients break RD PVR ≥C1 was conducted. All underwent a standard 3-port 20-gauge pars plana (PPV) gas or silicone oil tamponade without supplementary scleral buckling. The vitreous all membrane were completely removed, retinectomy...
The present study aims to investigate the effects of nourishing "Yin" and purging "Fire" Traditional Chinese Medicine (TCM) herb mixture on precocious puberty TCM may act through hypothalamic Lin28/let7 pathway expression in model rats. Meanwhile, confirm relationship between by overexpression Lin28a, first part this study, female rats were randomly allocated into untreated controls, (PP) group, PP control + group. Rats postnatal day 5 injected danazol establish model. From days 15 35, group...
To discuss the mechanism of Yiqiyangyin recipe in rats with adriamycin (ADR)-induced nephropathy. We randomly divided 30 Sprague-Dawley into 5 groups: control, model, glucocorticoid, Chinese herb, and herb plus glucocorticoid groups. The 24-h urine volume was collected on days 7, 14, 21, 28 after ADR injection, all were killed day 28. measured levels urinary protein, serum cholesterol, triglycerides, renal function by using routine biochemical methods. Pathological changes rat kidneys...
To explore the regulatory effects of established Chinese herbal formulas on inflammatory mediators released during asthma attacks, and to elucidate molecular mechanism Traditional Medicine in treatment asthma.Seventy-five asthmatic children were randomly divided into a medication group (45 cases) Western control (30 cases). Patients treated with series formulas, whereas received leukotriene receptor antagonist bronchial relaxant. Real-time PCR was used determine mRNA expression levels...
Background: Potent immune-suppressive therapy has been demonstrated to increase the risk of infective endocarditis (IE) in renal recipients. Reports Corynebacterium striatum ( C. ) recipients are scarce, thus limiting understanding disease. Case Presentation: We describe a case native valve caused by 35-year-old male patient. The young man with end-stage failure underwent kidney transplantation because autosomal dominant polycystic Ceftazidime was administered after surgery according routine...
Background Donor and recipient risk factors on graft function have been well characterized. The contribution of demographic factors, such as age, gender, other potential donor at the time transplantation a is much less understood. In this study, we analyzed effects etc., short-term long-term in kidney transplant recipients from living donor. Methods A total 335 donors their recipients, who had our center May 2004 to December 2009, were included. Serum creatinine level was used assessment...
To evaluate the effect of ZiYin Xiehuo granules (ZYXH) and Zishen Qinggan (ZSQG) on partial precocious puberty (PPP). This was a multicenter, randomized, single-blind, positive-controlled trial. A total 143 patients were assigned to either ZYXH group or ZSQG using random number table. The received three times daily for 6 months months. Mammary nucleus diameter; results uterus, ovarian, maximum follicle measures; Chinese medicine symptom pattern scores compared at baseline after 3 treatment....
Background Advances in transplantation immunology show that the balance between dendritic cells (DCs) and their subsets can maintain stable immune status induction of tolerance after transplantation. The aim this study was to investigate if DCs DC subpopulations recipient peripheral blood are effective diagnostic indicators acute rejection following kidney Methods Immunofluorescent flow cytometry used classify white (WBCs), levels mononuclear (including dominant subpopulations, plasmacytoid...