A5100672282- Reproductive Biology and Fertility
- Child and Adolescent Psychosocial and Emotional Development
- Early Childhood Education and Development
- Immune Cell Function and Interaction
- CAR-T cell therapy research
- Animal Genetics and Reproduction
- Empathy and Medical Education
- Cell death mechanisms and regulation
- Reproductive System and Pregnancy
- Child Abuse and Trauma
- Attachment and Relationship Dynamics
- Pain Mechanisms and Treatments
- Multiple Myeloma Research and Treatments
- Esophageal Cancer Research and Treatment
- Coronary Artery Anomalies
- Cancer-related gene regulation
- Lung Cancer Diagnosis and Treatment
- Cultural Differences and Values
- Optimism, Hope, and Well-being
- Pain Management and Placebo Effect
- Kawasaki Disease and Coronary Complications
- Lung Cancer Treatments and Mutations
- Acupuncture Treatment Research Studies
- Respiratory viral infections research
- Humor Studies and Applications
Zunyi Medical University
2024-2025
Hebei Medical University
2025
Shanghai Normal University
2024
Capital Normal University
2017-2024
Taipei City Hospital
2023-2024
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2024
Columbia University
2024
Thomas Jefferson University
2024
Sidney Kimmel Cancer Center
2024
Zhejiang Chinese Medical University
2023
This study conceptualizes a cultural model of parenting. It is argued that models are expressed in the degree familism, which informs socialization goals embodied parenting ethnotheories. Three were differentiated priori: independent, interdependent, and autonomous-related. Samples recruited expected to represent these models: German, Euro-American, Greek middle-class women representing independent model; Cameroonian Nso Gujarati farming interdependent urban Indian, Chinese, Mexican, Costa...
Ovarian follicular atresia represents a selection process that ensures the release of only healthy and viable oocytes during ovulation. The transition from preantral to early antral stage is penultimate development in terms gonadotropin dependence follicle destiny (survival/growth vs. atresia). We have examined whether how oocyte-derived growth differentiation factor 9 (GDF-9) FSH regulate transition, by novel combination vitro gene manipulation (i.e. intraoocyte injection GDF-9 antisense...
Objective To determine the effectiveness of a narrative medicine educational intervention on empathic abilities and academic achievement Chinese nursing students. Methods A cluster randomised controlled trial was conducted between January 2015 July 2017. Six class clusters (two controls, four interventions) comprising 180 students were included in this trial. After pre-tests to obtain baseline measurements, two control classes (Group 1) attended regular medical education courses, 2) received...
Abstract Background Drunkenness and alcoholic liver disease (ALD) are critical public health issues associated with significant morbidity mortality due to chronic overconsumption of alcohol. Traditional remedies, such as bear bile powder, have been historically acclaimed for their hepatoprotective properties. This study assessed the efficacy a biotransformed powder known golden (GBP) in alleviating alcohol-induced drunkenness ALD. Methods A murine model was engineered simulate alcohol acute...
Chiral sulfoxides are essential in fields of pharmaceutical industry and asymmetric synthesis, requiring high enantioselectivity for their diverse applications. Biocatalytic methods, utilizing oxidases (e.g., BVMO, P450MO) reductases Msr, DMSO reductase), have proven to be efficient sustainable alternatives chemical synthesis. This review highlights progress made over the past decade enzymatic approaches, including oxidation, kinetic resolution, cascade catalysis, with contributions from...
Introduction In thyroid carcinoma (TC), follicular (FTC) represents the second most prevalent pathological type following papillary carcinoma. Notably, FTC exhibits a more aggressive clinical course and higher propensity for distant metastasis. However, underlying mechanisms governing progression of remain poorly understood. PMAIP1 is gene implicated in various cancers biological processes. Investigating role mechanism crucial enhancing our understanding informing treatment strategies....
Children's socialization environments reflect cultural models of parenting. In particular, Euro-American and Chinese families have been described as following different scripts. The present study assesses parenting behaviors well ethnotheories with respect to three-month-old babies in middle-class Los Angeles Beijing. parents' towards their children, parental are assumed express the model autonomy; whereas strategies be shaped by relatedness. results reveal that mothers embody verbal...
The empathy of doctors is closely related to patients' outcomes. This research aimed examine whether stigma, self-efficacy, and anxiety mediate the relationship between doctors' cellular immunity in patients with advanced prostate cancer treated by orchiectomy.Data on demographics, disease condition, were collected. Patients' psychological indicators measured at admission, after 14 days, 3 months. variance analysis test was used compare immune indices three time points. At T3, a multivariate...
Pain memory is commonly considered an underlying cause of chronic pain and also responsible for a range anxiety. Electroacupuncture (EA) has been shown to ameliorate memories exert anti-anxiety effects. Previous research indicated that GABAergic neurons and/or GABA receptors (GABARs) in the midcingulate cortex (MCC) have potential associations with However, there no known empirical specifically studied effects EA on system MCC. Here, we used cross-injection carrageenan establish rats model....
Increased X-linked inhibitor of apoptosis (XIAP) expression and suppressed follicular are important determinants in the regulation development by FSH. The objective present study was to examine role nuclear factor-κB (NFκB) gonadotropic control granulosa cell XIAP growth vitro. FSH (100 ng/ml) increased rat mRNA abundance protein content. gonadotropin also induced p65 subunit-containing NFκB translocation from cytoplasm nucleus NFκB-DNA binding activity. Supershift EMSA indicated...
X-linked inhibitor of apoptosis protein (XIAP) in granulosa cells is regulated by gonadotropins during follicular development, although the current understanding mechanisms which XIAP suppressed cell incomplete. In present study, we investigated possible involvement phosphatidylinositol 3-kinase (PI 3-K) survival pathway regulation fate. Using a fully characterized vivo model to study induction development and atresia immature rats, have demonstrated that gonadotropin treatment increased...
Depression is a chronic, recurring and potentially life-threatening illness. Current treatments for depression are characterized by low success rate associated with wide variety of side effects. The aim the present study was to evaluate behavioral anti-depressant effect novel herbal compounds named ziziphi spinosae lily powder suspension, as well investigate its potential mechanisms.Except body weight, depressive-like behaviors were also evaluated using forced swimming test, sucrose...
Medical staff's empathy is closely related to patients' outcome. This research aimed verify the influence of Chinese oncology nurses' on cellular immunity lung cancer patients.The study included 365 patients, who were attended by 30 nurses between October 2016 and May 2017. At time admission discharge, flow cytometric analysis was used measure including T-cell subsets natural killer (NK)-cell activity. The level measured Jefferson Scale Empathy (JSE, version). divided into high, moderate,...
The development of acquired resistance to small molecule tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) signaling has hindered their efficacy in treating non-small cell lung cancer (NSCLC) patients. Our previous study showed that constitutive activation the 70 kDa ribosomal protein S6 1 (S6K1) contributes EGFR-TKIs NSCLC lines and xenograft tumors nude mice. However, regulatory mechanisms underlying S6K1 TKI-resistant cells have not yet been explored. In...
Severe fever with thrombocytopenia syndrome (SFTS), one kind of tick-borne acute infectious disease, is caused by a novel bunyavirus. The relationship between meteorological factors and diseases hot topic current research. Liaoning Province has reported high incidence SFTS in recent years. However, the epidemiological characteristics its province remain largely unexplored.Data on cases were collected from 2011 to 2019. Epidemiological analyzed. Spearman's correlation test generalized linear...
The expression of X-linked inhibitor apoptosis protein (XIAP), a member family intracellular antiapoptotic proteins, is induced by FSH during follicular development in vivo. Whether the XIAP up-regulation (100 ng/ml) direct action gonadotropin and important control granulosa cell proliferation growth unclear. overall objective present study was to examine whether FSH-induced mediated secretion intraovarian transforming factor α (TGFα). In rat follicles cultured for 2 4 days, stimulated...
The pro-inflammatory potency and causal relationship with asthma of inhaled endotoxins have underscored the importance accurately assessing endotoxin content organic dusts. Limulus amebocyte lysate (LAL) assay has emerged as preferred assay, but its ability to measure in intact bacteria dusts similar sensitivity purified is unknown. We used metabolically radiolabeled Neisseria meningitidis both rough smooth Escherichia coli compare dose-dependent activation LAL from these shed outer membrane...
This study aimed to identify clinical characteristics differentiate multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease (KD) Taiwan, an island with a delayed cluster of MIS-C high incidence KD. Additionally, we studied risk factors for developing severe complications patients MIS-C.
Background Hand-Foot-and-Mouth-Disease (HFMD) has been widely spread in Asia, and result a high disease burden for children many countries. However, the dissemination characteristics intergroup between different age groups are still not clear. In this study, we aim to analyze differences transmissibility of HFMD, whole population among Shenzhen city, by utilizing mathematical models. Methods A database that reports HFMD cases city from January 2010 December 2017 was collected. first stage,...
Abstract Introduction: Multiple myeloma (MM) is an incurable hematologic malignancy and new strategies that offer a chance of obtaining long-term progression free survival are urgently needed. MM associated with profound immune alterations dysfunction natural killer (NK) cells have been demonstrated to be crucial factors in progression. Myeloma susceptible killing by but acquire the ability elude NK cell surveillance avoiding recognition suppressing function. Given role pathogenesis MM,...
Hyperglycemia in pregnancy (HIP) is a high-glycemic state that occurs during pregnancy, and gestational diabetes mellitus (GDM) the major cause of it. Studies reveal GDM has long-term adverse impacts on mothers offspring, such as maternal type 2 diabetes, premature birth stillbirth newborns, cardiovascular disease, metabolic disorders adult offspring. In recent years, studies transcription level metabonomics have provided new insights into pathophysiological mechanism GDM. This article...