A5013036032- Heat shock proteins research
- Biochemical effects in animals
- Neuroscience and Neuropharmacology Research
- Mitochondrial Function and Pathology
- Alzheimer's disease research and treatments
- Mesenchymal stem cell research
- Anesthesia and Neurotoxicity Research
- Neonatal and fetal brain pathology
- Genetics, Aging, and Longevity in Model Organisms
- Spaceflight effects on biology
- Neuroinflammation and Neurodegeneration Mechanisms
- Calpain Protease Function and Regulation
- S100 Proteins and Annexins
- Biochemical Analysis and Sensing Techniques
- Aquaculture Nutrition and Growth
- Science and Education Research
- Drug Transport and Resistance Mechanisms
- Cardiac Ischemia and Reperfusion
- Linguistics and Education Research
- dental development and anomalies
- Cell death mechanisms and regulation
- Spinal Cord Injury Research
- Spinal Hematomas and Complications
- Neurological Disorders and Treatments
- Bone and Dental Protein Studies
Universidade Federal do Rio Grande do Sul
2003-2022
University College London
2004-2009
Royal College of Surgeons of England
2004
Universidade Federal de Santa Maria
1999
Spontaneous intracerebral hemorrhage (ICH) is the most devastating type of stroke and a leading cause disability mortality worldwide. Although rehabilitation improves recovery after ICH cellular mechanisms involved are poorly understood. We decided to examine if skilled (SK) unskilled (US) training sham or surgeries would induce GFAP+ astrocytic changes whether these modifications can be associated with functional improvement. A 4-week course motor training, involving either began seven days...
Heat shock protein 27 (HSP27) has a major role in mediating survival responses to range of central nervous system insults, functioning as chaperone, an antioxidant, and through inhibition cell death pathways. We have used transgenic mice overexpressing HSP27 (HSP27tg) examine the cerebral ischemia, using model permanent middle artery occlusion (MCAO). Infarct size was evaluated multislice T 2 -weighted anatomical magnetic resonance imaging (MRI) after 24 h. A significant reduction 30%...
Cell transplantation is a promising experimental treatment for spinal cord injury. The aim of the present study was to evaluate efficacy mononuclear cells from human umbilical blood in promoting functional recovery when transplanted after contusion Female Wistar rats (12 weeks old) were submitted injury with MASCIS impactor and divided into 4 groups: control, surgical injury, one cell-treated lesion group. Mononuclear male neonates two experiments: a) 1 h surgery, site at concentration 5 x...
The purpose of the present study was to investigate in vitro and vivo effects aluminum sulfate on delta-aminolevulinic acid dehydratase (ALA-D) activity from brain, liver kidney adult mice (Swiss albine). In experiments showed that concentration needed inhibit enzyme 1.0-5.0 mM (N = 3) 4.0-5.0 0.0-5.0 kidney. were performed three groups for one month: 1) control animals 8); 2) treated with 1 g% (34 mM) sodium citrate 8) plus 3.3 (49.5 8). Exposure drinking water inhibited ALA-D (23.3 ± 3.7%,...
In recent years organotypic slice cultures of hippocampal tissue rats have been widely used to study factors involved in neuronal death. Here we 2D electrophoresis the phosphoprotein profile such and effect oxygen/glucose deprivation on this profile. Cultures were prepared from 7-day-old rats. After 14 days culture phosphorylation cultures, as shown by phospho- protein markers undergoing developmental change, closely resembled fresh 23-day-old The results suggest that model could be a good...