- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Vascular Malformations and Hemangiomas
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cerebrovascular and Carotid Artery Diseases
- Supercapacitor Materials and Fabrication
- Dialysis and Renal Disease Management
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Valve Diseases and Treatments
- Acute Kidney Injury Research
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- Aquaculture Nutrition and Growth
- Renal and Vascular Pathologies
- Aquaculture disease management and microbiota
- Advancements in Battery Materials
- Pulmonary Hypertension Research and Treatments
- Aortic Thrombus and Embolism
- Advanced Nanomaterials in Catalysis
- Gas Sensing Nanomaterials and Sensors
- Breast Implant and Reconstruction
China-Japan Friendship Hospital
2011-2025
Hebei Medical University
2025
Xingtai People's Hospital
2025
Peking University
2021-2024
Southwest Jiaotong University
2024
Qiqihar University
2021-2023
Xiamen University
2020-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2017
Guangzhou First People's Hospital
2012
Guangzhou Medical University
2012
Abstract Hyperuricemia closely correlates with the development of atherosclerosis, but little is known mechanism by which atherosclerosis progression occurs in hyperuricemia. Atherosclerosis appears to involve pyroptosis, an emerging proinflammatory regulated cell death. This study tested hypothesis that pyroptosis underlies relationship between hyperuricemia and using ApoE −/− mice (a model atherosclerosis), human umbilical vein endothelial cells (HUVECs), atherosclerotic arterial samples....
Background Aorto-caval fistula is a rare complication of abdominal aortic aneurysms that can occur spontaneously, iatrogenically, or traumatically, associated with high morbidity and mortality. Endovascular stent graft repair represents practical approach to managing this fatal condition. Case presentation A 75-year-old male patient was admitted the nephrology department our hospital, complaining acute back pain, hematuria, repeated vomiting for one week. The laboratory assessments yielded...
Immune-mediated inflammatory diseases (IMIDs) have been associated with an increased risk of venous thromboembolism (VTE) in multiple observational studies. However, a direct causally relation between IMIDs and VTE remains unclear to date. Here, we used Mendelian randomization (MR) analysis investigate causal associations VTE.We collected genetic data from published genome-wide association studies (GWAS) for six common IMIDs, specifically bowel disease (IBD), Crohn's (CD), ulcerative colitis...
Hybrid transition metal oxides and redox graphene nanocomposites are ideal materials for electrochemical sensors energy storage devices. Nevertheless, the successful synthesis of with excellent properties good synergistic catalytic is still facing significant challenges. In this article, multistep hydrothermal method was used to synthesize performance 3-D nanoflower-like ZnO/MoS2/rGO composite, which successfully overcame above challenges improved all-around nanocomposites. The material has...
Varicose veins are a common problem worldwide and can cause significant impairments in health-related quality of life, but the etiology pathogenesis remain not well defined. This study aims to elucidate transcriptomic regulations varicose by detecting differentially expressed genes, pathways regulator genes.We harvested great saphenous (GSV) from patients who underwent coronary artery bypass grafting (CABG) conventional stripping surgery. RNA-Sequencing (RNA-Seq) technique was used obtain...
Abstract It is difficult to manage tributary varicose veins with endovenous laser ablation. Using the intravenous catheter-guided fiber ablate has been proposed. From April 2004 December 2009, we randomly assigned 134 patients 170 limbs for therapy, of which, 89 in 74 were treated The residual tortuous abolished ablation (ICLA group), whereas 81 60 by stab avulsion (SA group). Patients followed up median 44.5 months after surgery. outcomes and durability treatment both groups evaluated....
Angiogenesis plays a critical role in the progression and vulnerability of atherosclerotic plaques; however, orchestration angiogenesis plaque formation remains unclear. The results microarray analysis, real-time PCR immunohistochemical analyses showed that Hairy/enhancer split homologue-1 (Hes-1) expression was significantly decreased, while osteopontin (OPN) increased, plaques. Meanwhile, immunofluorescence demonstrated both Hes-1 OPN were expressed endothelial cells (ECs) neovessels an...
Objective To evaluate the safety and efficacy of bleomycin polidocanol foam (BPF) sclerotherapy for venous malformations (VMs) analyze associated clinical outcomes predictors. Methods We retrospectively assessed BPF in 138 patients with VMs. analyzed pain levels, lesion volume reduction, subjective perception response. Logistic regression analysis was performed to identify potential predictors treatment outcome. Additionally, we carefully monitored recorded complications. Results There a...
Background: Identifying effective pharmacological interventions to prevent the progressive enlargement and rupture of aortic aneurysms (AAs) is critical. Previous studies have suggested links between metformin use a decreased incidence AAs. In this study, we employed Mendelian randomization (MR) investigate causal effects metformin's targets on AA risk explore underlying mechanisms these effects. Methods: To examine relationship risk, implemented both two-sample MR multivariable analyses....
Abstract Background Drug-coated balloons (DCBs) have shown superiority in the endovascular treatment of short femoropopliteal artery disease. Few studies focused on outcomes long lesions. This study aimed to evaluate safety and effectiveness Orchid ® DCBs lesions over 1 year follow-up. Methods is a multicentre cohort real-world study. The patients had longer than or equal 150 mm were revascularized with DCBs. primary endpoints patency, freedom from clinically driven target lesion...
Background Deep hypothermic circulatory arrest (DHCA) is nowadays commonly used in pulmonary thromboendarterectomy (PTE). Neurological injury related to DHCA severely impairs the prognosis of patients. However, risk factors and predictors neurological are still unclear. Methods We conducted a prospective observational study, including 82 patients diagnosed as chronic thromboembolic hypertension underwent PTE alone our center from December 2016 May 2021. Demographic characteristics, clinical...
Objective: Abdominal aortic aneurysm (AAA) refers to unusual permanent dilation of the abdominal aorta, and gradual AAA expansion can lead fatal rupture. However, we lack clear understanding pathogenesis this disease. The effect perivascular adipose tissue (PVAT) on vascular functional status has attracted increasing attention. Here, try identify potential mechanisms linking PVAT. Methods: We downloaded dataset GSE119717, including 30 dilated PVAT samples non-dilated aorta from cases, Gene...
The aim of this study is to compare the rate primary patency and secondary achieved by ulnar-basilic arteriovenous fistula (UBAVF) radiocephalic (RCAVF) in maintenance hemodialysis access.This retrospective analysis consists 365 patients who had a forearm UBAVF or RCAVF between January 2012 December 2015. Of these patients, 44 were treated with UBAVF, while 321 RCAVF. Demographics, patency, documented compared.Primary rates at 1 2 years 77.2% 63.9% group 88.1% 71.3% RCAVF, respectively....
Arteriovenous fistulas (AVFs) are the preferred vascular access for hemodialysis of patients with end-stage renal disease. However, there is a high incidence AVF failures caused by insufficient outward remodeling or venous neo-intimal hyperplasia formation. Abnormal proliferation and migration smooth muscle cells (VSMCs) play an important role in many cardiovascular diseases. VSMC could be abolished inhibition mitochondrial division.We found that abnormal VSMCs increased fission were...
Intraplaque hemorrhage (IPH) is an important feature of unstable plaques and independent risk factor for cardiovascular events. However, the molecular mechanisms contributing to IPH are incompletely characterized. We aimed identify novel biomarkers interventional targets characterize role immune cells in pathogenesis.The microarray dataset GSE163154 which contain non-IPH plaque samples was obtained from Gene Expression Omnibus (GEO). R software adopted identifying differentially expressed...