A5009005944- Parasitic Infections and Diagnostics
- Pneumocystis jirovecii pneumonia detection and treatment
- Toxoplasma gondii Research Studies
- Service-Learning and Community Engagement
- Bullying, Victimization, and Aggression
- Counseling Practices and Supervision
- Amoebic Infections and Treatments
- Parasitic infections in humans and animals
- Diverse Education Studies and Reforms
- Paleopathology and ancient diseases
- Mollusks and Parasites Studies
- Veterinary medicine and infectious diseases
- Diptera species taxonomy and behavior
University of Glasgow
2024
Wellcome Centre for Anti-Infectives Research
2023-2024
University of Dundee
2023-2024
Wellcome Centre for Molecular Parasitology
2024
Introduction Cryptosporidiosis is a leading cause of diarrheal-associated morbidity and mortality, predominantly affecting children under 5 years old in low-and-middle-income countries. There no effective treatment vaccine. New therapeutics are emerging from drug discovery efforts. It critical that mode action studies performed alongside to ensure the best clinical outcomes. Unfortunately, technology identify validate targets for Cryptosporidium severely lacking. Methods We used C. parvum...
Cryptosporidiosis is a diarrheal disease caused by infection with Cryptosporidium spp. parasites and leading cause of death in malnourished children worldwide. The only approved treatment, nitazoxanide, has limited efficacy this at-risk patient population. Additional safe therapeutics are urgently required to tackle unmet medical need. However, the development anti-cryptosporidial drugs hindered lack understanding optimal compound properties treat gastrointestinal infection. To address...
Abstract Cryptosporidiosis is a significant cause of diarrhoeal disease contributing to substantial morbidity and mortality for the immunocompromised young children, especially those who are malnourished. There no vaccines available effective treatments these patients. Another challenge that Cryptosporidia waterborne resistant common water including chlorination. transmitted as an oocyst made up hardy wall protects four parasites. Little understood about how constructed, its composition, it...