A5015054115- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Advances in Oncology and Radiotherapy
- Management of metastatic bone disease
- Ovarian cancer diagnosis and treatment
- Medical Imaging Techniques and Applications
- Cervical Cancer and HPV Research
- Radiation Therapy and Dosimetry
- Brain Metastases and Treatment
- Effects of Radiation Exposure
- Cancer Immunotherapy and Biomarkers
- Radiation Dose and Imaging
- Global Cancer Incidence and Screening
- Cancer survivorship and care
- Cancer Diagnosis and Treatment
- Pharmaceutical industry and healthcare
- Lung Cancer Research Studies
- Breast Lesions and Carcinomas
- Prostate Cancer Treatment and Research
- Endometriosis Research and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiopharmaceutical Chemistry and Applications
- Cancer-related Molecular Pathways
- Sarcoma Diagnosis and Treatment
University of Pennsylvania
2017-2025
Hospital of the University of Pennsylvania
2020-2024
California University of Pennsylvania
2018-2024
University of California, Los Angeles
2024
Spanish Oncology Genitourinary Group
2024
Stellar Science (United States)
2024
Advanced Radiation Therapy (United States)
2024
Gynecologic Oncology Group
2024
NYU Langone Health
2024
University of Pennsylvania Health System
2020-2023
153 Background: Metastatic castration-resistant prostate cancer (mCRPC) remains an incurable and fatal disease. Administration of Lu-PSMA demonstrates improved progression free survival overall in this population (1). Despite this, understanding patient access to receipt therapy is understudied. We aim characterize the demographics patients receiving at a NCI-designated medical center Philadelphia, PA after FDA approval. Methods: All treated single institutional with from April 2023 October...
Radiation therapy (RT) improves breast cancer outcomes, but cardiac morbidity remains a concern. This study sought to evaluate changes in function after RT and the relationship between dose metrics echocardiography-derived measures of function. In longitudinal cohort women with cancer, radiation core lab quantitated echocardiographic were evaluated. Dose included whole heart, left ventricle, right anterior descending artery (LAD). Echocardiographic ventricular ejection fraction (LVEF),...
OBJECTIVE The aim of this study was to report the first detailed analysis patterns failure within spinal axis patients treated with stereotactic body radiotherapy (SBRT) for sarcoma spine metastases. METHODS Between 2005 and 2012, 88 consecutive metastatic were SBRT 120 lesions. Seventy-one percent enrolled on prospective institutional protocols. For who underwent routine posttreatment total-spine MRI (64 patients, lesions), each site progression entire mapped in relation lesion. Actuarial...
Compared with conventional external-beam radiation therapy (cEBRT) for patients breast cancer (BC) and prostate (PC), shorter regimens may be associated lower treatment noncompletion rates. We assess disparities in receipt of BC PC.
Radiation-induced fatigue is a common side effect of breast cancer radiotherapy (RT). This study compares the induction and persistence radiation-induced in accelerated partial irradiation (APBI), hypofractionated RT, standard whole RT.Eighty patients were treated with novel, 3-week regimen 333 centigrays (cGy) for 15 fractions to 4995 cGy; these, 45 using APBI, whereas 35 RT. These matched receiving 200 cGy 30 irradiation. Fatigue score, Common Terminology Criteria Adverse Events version...
Imaging criteria to evaluate the response of brain metastases stereotactic radiosurgery (SRS) in early posttreatment period remains a crucial unmet need. The aim this study is correlate (within 12 wk) perfusion MRI changes with long-term outcomes after treatment lung cancer SRS.Pre- and scans were obtained patients treated SRS for intact non-small cell metastases. Time-dependent leakage (Ktrans), blood plasma volume (Vp), extracellular extravascular (Ve) calculated each lesion. Patients...
Cyclin-dependent kinase (CDK)4/6 inhibitor is a first-line therapy for metastatic ER+/HER2-breast cancer. However, there are limited data on safety of combined radiotherapy (RT) and CDK4/6 inhibition.We conducted retrospective study women with breast cancer who received palliative RT within 14 days use. The primary endpoint was toxicity per Common Terminology Criteria Adverse Events v5. Secondary endpoints were pain response local control based clinical assessment imaging.Thirty patients...
Superficial dose is an important parameter in breast cancer radiation therapy. When treated with conventional linacs, bolus commonly applied to improve target coverage near the surface while also managing risk of severe skin reactions and negative cosmesis. With introduction modern linacs 6X flattening filter free (FFF) photon beams, effect on superficial need for must be evaluated.In vivo measurements were made optically stimulated luminescence dosimeters 11 patients Halcyon FFF linac...
PurposeOptimal integration of local therapy and systemic immune for patients with mucosal melanoma (MM) is uncertain. We evaluated treatment patterns outcomes following radiation (RT) in combination checkpoint inhibition (ICI) MM.MethodsThirty-seven localized (n=32, 87%) or node positive (n=5, 14%) MM were treated across 4 institutions RT to the primary tumor without oncologic resection (n=28, 76%) ICI from 2012-2020. Recurrence rates estimated using cumulative incidence presence competing...