A5087963406- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- Aortic aneurysm repair treatments
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Treatments and Studies
- Infectious Aortic and Vascular Conditions
- Intestinal and Peritoneal Adhesions
- Parathyroid Disorders and Treatments
- Muscle and Compartmental Disorders
- Bone fractures and treatments
- Esophageal and GI Pathology
- Cancer-related molecular mechanisms research
- Tribology and Wear Analysis
- Therapeutic Uses of Natural Elements
- Lung Cancer Treatments and Mutations
- AI in cancer detection
- Diet, Metabolism, and Disease
- Vascular Procedures and Complications
- Advanced NMR Techniques and Applications
- Intramuscular injections and effects
- Cell Adhesion Molecules Research
- Liver Disease Diagnosis and Treatment
- Viral-associated cancers and disorders
Icahn School of Medicine at Mount Sinai
2025
Weill Cornell Medicine
2024
Children's Cancer and Blood Foundation
2024
Cornell University
2024
Memorial Sloan Kettering Cancer Center
2018-2023
Washington University in St. Louis
2020
Jewish Hospital
2020
Barnes-Jewish Hospital
2020
Johns Hopkins University
2017-2018
Johns Hopkins Bayview Medical Center
2018
The liver is a frequent site of benign and malignant, primary metastatic tumors. Hepatocellular carcinoma (HCC) intrahepatic cholangiocarcinoma (ICC) are the most common cancers, colorectal metastasis (CRLM) secondary cancer. Although imaging characteristic these tumors central to optimal clinical management, it relies on features that often non-specific, overlap, subject inter-observer variability. Thus, in this study, we aimed categorize automatically from CT scans using deep learning...
Abstract Changes in the elastic properties of living tissues during normal development and pathological processes are often due to modifications collagen component extracellular matrix at various length scales. Force volume AFM can precisely capture mechanical biological samples with force sensitivity spatial resolution. The integration data molecular composition contributes understanding interplay between tissue biochemistry, organization function. detection micrometer-size, heterogeneous...
282 Background: Approximately 50% of patients with colorectal cancer develop liver metastases (CRLM). The incidence early onset (EOCRC), defined as <50 years age at time diagnosis, is increasing. In this study, we aim to explore the prognosis vs late CRLM who receive curative-intent treatment. Methods: A retrospective study was conducted assess clinical outcomes in presenting EOCRC compared those (LOCRC). All underwent surgical resection and/or ablation between 2009 and 2024 a tertiary...
The ability to break down fructose is dependent on ketohexokinase (KHK) that phosphorylates fructose-1-phosphate (F1P). We show KHK expression tightly controlled and limited a small number of organs down-regulated in liver intestinal cancer cells. Loss metabolism also apparent hepatocellular adenoma carcinoma (HCC) patient samples. overexpression cells results decreased flux through glycolysis. then developed strategy detect this metabolic switch vivo using hyperpolarized magnetic resonance...
Abstract Background The aim of this study was to investigate the effectiveness adjuvant hepatic arterial infusion pump (HAIP) chemotherapy after complete resection or ablation recurrent colorectal liver metastases (CRLM). Methods A retrospective cohort conducted patients from two centers who were treated with and/or CRLM only between 1992 and 2018. Overall survival (OS) disease-free (hDFS) estimated using Kaplan–Meier method. Cox regression method used calculate hazard ratios (HRs)...
Abstract Background After resection of colorectal liver metastases (CRLM), recurrent disease in the is a major cause death but may be reduced with addition adjuvant hepatic arterial infusion (HAI) chemotherapy to systemic (SYS). Objective This study investigates organ‐specific causes patients receiving HAI and SYS compared alone. Methods Between 2000 2007, undergoing complete CRLM were identified from prospectively maintained database categorized as + or only. Using newly constructed...
This study investigated the effect of reduced dose systemic chemotherapy (SYS) on recurrence patterns in patients receiving adjuvant hepatic artery infusion (HAI) after complete colorectal liver metastases (CRLM) resection.Patients undergoing CRLM resection between 2000 and 2007 were selected from a prospectively maintained database categorized as SYS or HAI + SYS. Those with pre and/or intraoperative extrahepatic disease, documented death, within 30 days excluded. Competing risk, Fine...
BACKGROUND: Intravenous drug abusers (IVDA) are at an increased risk of developing infected peripheral pseudoaneurysms. The aim this study is to describe a group IVDA patients who present with pseudoaneurysms and evaluate the outcomes vascular surgery reconstruction in population. MATERIALS AND METHODS: A retrospective all presenting between 2009 2015 premier healthcare database 2009–2015 were identified. Patients' demographics, comorbidities, along procedures performed, in-hospital...