A5046960709- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Appendicitis Diagnosis and Management
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Congenital Anomalies and Fetal Surgery
- Viral-associated cancers and disorders
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- Parasitic infections in humans and animals
- Organ Donation and Transplantation
- Surgical Simulation and Training
- Parasitic Infections and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Transplantation: Methods and Outcomes
- Abdominal Trauma and Injuries
Groote Schuur Hospital
2019-2024
University of Cape Town
2018-2024
Washington University in St. Louis
2018-2024
Abdominal organ transplantation faces several challenges: burnout, limited pipeline of future surgeons, changes in liver allocation potentially impacting procurement travel, and travel safety. The center (OPC) model may be one way to mitigate these issues. Liver transplants from 2009 2016 were reviewed. There 755 performed with 525 OPC 230 in-hospital procurements. majority (87.4%) started during daytime hours (5 am-7 pm). Transplants any portion occurring after-hours more likely have...
The number of patients on the liver transplant waitlist continues to grow and far exceeds livers available for transplantation. Normothermic machine perfusion (NMP) allows ex-vivo under physiologic conditions with potential significantly increase organ yield expand donor pool.
Treatment of major iatrogenic and non-iatrogenic bile duct injury (BDI) often requires delayed surgery with interim external biliary drainage. Percutaneous transhepatic cholangiography (PTC) catheter placement endoscopic retrograde (ERC) stent have been used to bridge defects. In some patients, bridging the defect cannot be achieved through ERC or PTC alone.Two patients BDIs, one underwent an extraluminal PTC/ERC rendezvous a fully covered self-expandable metal (SEMS) for acute management...
There is a paucity of data from the developing world regarding laparoscopic cholecystectomy (LC) bile duct injuries (BDIs), despite fact that most world's population live in country. We assessed how referral patterns, management and outcomes after LC-BDI repair have evolved over time patients treated at tertiary center low middle-income country (LMIC).Patients with LC-BDIs requiring hepaticojejunostomy were identified prospective database. Clinical characteristics, geographic distance...
Primary liver cancer was the third most common cause of death due to worldwide in 2020. As predominant type, hepatocellular carcinoma (HCC) represents overwhelming majority newly diagnosed primary tumours. Liver transplantation remains treatment choice for a cure otherwise unresectable HCC. For nearly thirty years, Milan and Barcelona Clinic Cancer (BCLC) criteria have guided physicians' clinical decision-making selection transplant candidates More recently, studies demonstrated survival...
When laparoscopic cholecystectomy (LC) was introduced more than two decades ago, alarming rates of bile duct injuries (BDIs) occurred in up to 0.4% operations, twice as often as with open cholecystectomy, only a recent decrease incidence.1 Three contemporary studies from the National Health Service database the UK and statewide databases USA (New York California), report duct injury (LC-BDI) rates between 0.08–0.22%, which are comparable open cholecystectomy, but these estimations may not...
Few studies have reported patient outcome after surgical repair of bile duct injury using a standardized, validated classification system. This is the first analysis to investigate correlation between Anatomic, Timing Of and Mechanism severity postoperative complications classified Modified Accordion Grading System.Patients undergoing index hepaticojejunostomy in laparoscopic cholecystectomy at tertiary referral center from 1993-2018 were included. Patient demographics, geographic distance...
Background:The South African healthcare system has an under-financed public sector serving most of the population and a better resourced private small fraction population.This study evaluated management outcome in patients with complex bile duct injuries (BDIs) after laparoscopic cholecystectomy referred from either or hospitals.Methods: The data who underwent hepaticojejunostomy repair were retrieved prospectively maintained central departmental BDI database.Patients treated Surgical...