A5082720581- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Fibroblast Growth Factor Research
- Colorectal Cancer Treatments and Studies
- Pancreatitis Pathology and Treatment
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Liver Disease Diagnosis and Treatment
- Abdominal Trauma and Injuries
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Renal cell carcinoma treatment
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal disorders and treatments
- Epigenetics and DNA Methylation
- Gastrointestinal Tumor Research and Treatment
- Organ Transplantation Techniques and Outcomes
- Cancer Genomics and Diagnostics
- Nutrition and Health in Aging
Kepler Universitätsklinikum
2025
Salzburger Landeskliniken
2015-2025
Innsbruck Medical University
2016-2024
Kaiser-Franz-Josef-Spital
2008-2024
Gesundheit Österreich
2024
Universität Innsbruck
2016-2023
Queen Elizabeth Hospital Birmingham
2020-2023
University Hospitals Birmingham NHS Foundation Trust
2023
Paracelsus Medical University
2013-2021
European Institute of Oncology
2021
Abstract This ENETS guidance paper for well‐differentiated nonfunctioning pancreatic neuroendocrine tumours (NF‐Pan‐NET) has been developed by a multidisciplinary working group, and provides up‐to‐date practical advice on the management of these tumours. Using extensive experience centres treating patients with NF‐Pan‐NEN, authors this discuss 10 troublesome questions in everyday clinical practice. Our many years field are still being verified light results new clinical, which set ways...
Abstract Background Posthepatectomy liver failure (PHLF) contributes significantly to morbidity and mortality after surgery. Standardized assessment of preoperative function is crucial identify patients at risk. These European consensus guidelines provide guidance for patient assessment. Methods A modified Delphi approach was used achieve consensus. The expert panel consisted hepatobiliary surgeons, radiologists, nuclear medicine specialists, hepatologists. guideline process supervised by a...
Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim this project was to provide a practical framework for care metastases, focus on terminology, diagnosis, management.This multiorganizational, multidisciplinary consensus. consensus group produced statements which focused management. Statements were refined during an online Delphi process, those 70 per cent agreement or above reviewed at final meeting. Iterations the report shared by...
Abstract Fibroblast growth factors (FGFs) and their high-affinity receptors [fibroblast factor (FGFRs)] contribute to autocrine paracrine stimulation in several nonliver cancer entities. Here we report that at least one member of the FGF8 subfamily (FGF8, FGF17, FGF18) was up-regulated 59% 34 human hepatocellular carcinoma (HCC) samples investigated. The levels corresponding (FGFR2, FGFR3, FGFR4) were also elevated great majority HCC cases. Overall, 82% cases showed overexpression FGF and/or...
Background Combined intra-operative ablation and resection (CARe) is proposed to treat extensive colorectal liver metastases (CLM). This multicenter study was conducted evaluate overall survival (OS), local recurrence-free (LRFS), hepatic (HRFS) progression-free (PFS), identify factors associated with survival, report complications. Materials Methods Four centers combined retropectively their clinical experiences regarding CLM treated by CARe. characteristics, pre- post-operative...
A widespread shift to non-operative management (NOM) for blunt hepatic and splenic injuries has been observed in most centers worldwide. Furthermore, many countries introduced safety measures systematically reduce severe traffic leisure sports injuries. This study aims evaluate the effect of these nationwide implementations on individual patient characteristics outcomes through a time-trend analysis over 17 years an Austrian high-volume trauma center.A retrospective review all emergency...
Biliary tract cancers comprise a heterogeneous collection of malignancies usually described as cholangiocarcinoma the intra- or extrahepatic bile duct, including perihilar and gallbladder cancer.
Fibroblast growth factors (FGFs) and their high-affinity receptors contribute to the autocrine stimulation in several human malignancies. Here, we describe that FGF18 expression is up-regulated 34/38 colorectal tumours progressively enhanced during colon carcinogenesis reaching very high levels carcinoma. Moreover, our data suggest affects both tumour cells microenvironment a pro-tumorigenic pro-metastatic way. Addition of recombinant culture media slowly growing cell lines LT97 Caco-2...
Deregulation of fibroblast growth factor receptor 3 (FGFR3) is involved in several malignancies. Its role colorectal cancer has not been assessed before. Expression FGFR3 human tumour specimens was analysed using splice variant-specific real-time reverse transcriptase PCR assays. To analyse the impact FGFR3-IIIc expression on cell biology, colon models overexpressing wild-type (WT-3b and WT3c) or dominant-negative variants (KD3c KD3b) were generated by either plasmid transfection adenoviral...
Abstract Objectives Non-operative management (NOM) is increasingly utilised in blunt abdominal trauma. The 1994 American Association of Surgery Trauma grading (1994-AAST) applied for clinical decision-making many institutions. Recently, classifications incorporating contrast extravasation such as the CT severity index (CTSI) and 2018 update liver spleen AAST were proposed to predict outcome guide treatment, but validation pending. Methods images patients admitted 2000–2016 with splenic...
In Brief Objective: To investigate the effect of neuromuscular electrical stimulation (NMES) on skeletal muscle metabolism after major abdominal surgery. Summary Background Data: Protein catabolism associated with surgical interventions leads to reduced strength, increased clinical complications and prolonged convalescence. Immobilization is suggested as a stimulus for wasting. This study investigates potency NMES growth factors degradation processes in patients. Methods: observer blind...
Abstract Background The potential for a fibrin sealant patch to reduce the risk of postoperative pancreatic fistula (POPF) remains uncertain. aim this study was evaluate whether is able POPF in patients undergoing pancreatoduodenectomy with pancreatojejunostomy. Methods In multicentre trial, were randomized receive either (patch group) or no (control group), and stratified by gland texture, duct size neoadjuvant treatment. primary endpoint POPF. Secondary endpoints included complications,...
Management of benign liver tumours (BLT) is still object discussion. Uncertainty exists about patient selection, details management, indications for surgical intervention and potential surgery-related complications. The up-to-date strategies management the most common solid are recapitulated in this article. In addition, recommendations concerning practical issues presented. Available data from peer-reviewed publications associated with major controversies treatment BLT were selected through...
Despite evidence-based guidelines, exocrine pancreatic insufficiency is frequently underdiagnosed and undertreated in patients with chronic pancreatitis. Therefore, the aim of this study to provide insight into current opinion clinical decision-making international pancreatologists regarding management insufficiency. An online survey case vignette was sent experts pancreatitis members various associations: EPC, E-AHPBA DPSG. Experts were selected based on publication record from past 5...
The need for a common education and training track in surgical oncology across Europe has been emphasized. ESSO provides several hands-on courses skills face-to-face discussions. core curriculum framework the overall theoretical requirements oncology. UEMS/EBSQ fellowship exam is designed to test competencies candidate's knowledge their prespecified area of expertise. A set points each cancer type lacking. Hence, condensed outline themed expected be covered relevant an optimal practice...