- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Laser Applications in Dentistry and Medicine
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- Dermatologic Treatments and Research
- Liver Disease and Transplantation
- Inflammatory Biomarkers in Disease Prognosis
- Liver Disease Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Renal cell carcinoma treatment
- Gastrointestinal disorders and treatments
- Colorectal Cancer Treatments and Studies
- Infrared Thermography in Medicine
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Radiomics and Machine Learning in Medical Imaging
- Organ Transplantation Techniques and Outcomes
- Pituitary Gland Disorders and Treatments
- Abdominal Surgery and Complications
- Lung Cancer Research Studies
- MRI in cancer diagnosis
- Cancer Immunotherapy and Biomarkers
- Nutrition and Health in Aging
Medical University of Vienna
2015-2025
Comprehensive Cancer Center Vienna
2013-2023
University of Vienna
1998-2023
Vienna General Hospital
2010-2021
Vienna University of Economics and Business
2018
Fachhochschule Wiener Neustadt
2016
Universitätsklinik für Chirurgie Wien
1995-2011
Edinburgh Royal Infirmary
2005
Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery
1999-2000
General Electric (Austria)
1999
<b>Background and aims:</b> Major liver resection incurs a risk of postoperative dysfunction infection there is lack objective evidence relating residual volume to these complications. <b>Patients methods:</b> Liver volumetry was performed on computer models derived from computed tomography (CT) angioportograms 104 patients with normal synthetic function scheduled for resection. Relative (%RLV) calculated as the relation total functional related hepatic infection. Receiver operator...
The standardized Clavien-Dindo classification of surgical complications is applied as a simple and widely used tool to assess report postoperative in general surgery. However, most documentation uses this surgery-related morbidity mortality single field surgery or even particular intervention. aim the present study was experiences with when all patients on ward tertiary referral care center.We analyzed period 6 months broad range visceral Discharge reports patient charts were retrospectively...
OBJECTIVE Diabetic foot problems due to angiopathy and neuropathy account for 50% of all nontraumatic amputations constitute a significant economic burden society. Low-intensity laser irradiation has been shown induce wound healing in conditions reduced microcirculation. We investigated the influence low-intensity by means infrared thermography on skin blood circulation diabetic patients with microangiopathy. RESEARCH DESIGN AND METHODS Thirty consecutive ulcers or gangrenes elevated levels...
The systemic immune-inflammation index based on peripheral neutrophil, lymphocyte, and platelet counts has shown a prognostic impact in several malignancies. aim of this study was to determine the role patients with pancreatic ductal adenocarcinoma undergoing resection. Consecutive who underwent surgical resection at department surgery Medical University Vienna between 1995 2014 were included into study. calculated by formula platelet*neutrophil/lymphocyte. Optimal cutoffs determined using...
Background Incidence and mortality of pancreatic ductal adenocarcinoma (PDAC) are on the rise. Sarcopenia sarcopenic obesity have proven to be prognostic factors in different types cancers. In context previous findings, we evaluated impact body composition patients undergoing surgery a national center. Methods Patient's (n = 133) was analyzed diagnostic CT scans defined as follows: Skeletal muscle index ≤38.5 cm2/m2 (women), ≤52.4 (men); classified BMI ≥25kg/m2. Results showed negative...
Molecular taxonomy of tumours is the foundation personalised medicine and becoming paramount importance for therapeutic purposes. Four transcriptomics-based classification systems pancreatic ductal adenocarcinoma (PDAC) exist, which consistently identified a subtype highly aggressive PDACs with basal-like features, including ΔNp63 expression loss epithelial master regulator GATA6. We investigated precise molecular events driving PDAC progression emergence basal programme.
<h3>Hypothesis</h3> A prognostic scoring system for colorectal cancer liver metastases that is derived from unselected patients referred hepatic resection would improve the applicability and increase accuracy of prognostication. <h3>Design</h3> Retrospective analysis prospectively documented data; validation against an unrelated cohort another institution. The median follow-up was 16.4 months (95% confidence interval, 15.0-17.8 months) (original cohort). <h3>Setting</h3> Two tertiary...
Anamnesis data of 104 patients with Cystic Echinococcosis were correlated retrospectively the detected species/strain Echinococcus. Ninety-two percent ( N = 23) autochthonous Austrian and 33% 9) former Yugoslavian (YU) origin infected E. canadensis G7, pig strain. All originating from Turkey harbored granulosus G1, sheep G7-infected showed small liver cysts (ø 5.9 cm), only one them an additional lung cyst. The median age at time operation was 55 years, Turkish 30 YU 23 years in 42 -infected...
To determine if gadoxetic acid-enhanced magnetic resonance (MR) imaging with measurement of relative liver enhancement (RLE) on hepatobiliary phase images can allow preoperative assessment the risk failure after major resection.The local institutional review committee approved this retrospective analysis and waived written informed consent. The study included 73 patients (39 men; median age, 64.4 years) who underwent 3-T MR before resection three or more segments. RLE was calculated as ratio...
The purpose of our study was to assess the results hepatic artery embolization using N-butyl-2-cyanoacrylate and ethiodized oil for treatment small-bowel neuroendocrine metastases liver as part a multimodality protocol from tumors.Twenty-three patients underwent permanent cyanoacrylate Lipiodol after radical resection tumors. All received additional including somatostatin, most interferon well. Cumulative survival rates were estimated Kaplan-Meier method.Overall, 75 embolizations (range,...
The aim of this study was to assess the objective and subjective image characteristics monoenergetic images (MEI[+]), using a noise-optimized algorithm at different kiloelectron volts (keV) compared polyenergetic (PEI), in patients with pancreatic ductal adenocarcinoma (PDAC). This retrospective, institutional review board-approved included 45 (18 male, 27 female; mean age 66 years; range, 42–96 years) PDAC who had undergone dual-energy CT (DECT) abdomen for staging. One standard (PEI) five...
Introduction Postoperative pancreatic fistula (POPF) is the most frequent complication after partial pancreatectomy, which by definition associated with clinical consequences requiring changes in postoperative management. Despite numerous scientific efforts, effective procedures to prevent POPF are lacking. Obsidian ASG autologous platelet-rich fibrin matrix has been effectively applied anastomotic leakage following colorectal surgery. This study first investigate feasibility of using...
<b>Objective:</b> To evaluate the efficacy of low-intensity laser irradiation for induction wound healing a diabetic neuropathic foot ulcer. <b>Case:</b> We report case man with insulin-dependent diabetes mellitus, sensory neuropathy, macroangiopathy and microangiopathy who had been suffering from an ulcer his first left toe accompanied by osteomyelitis 6 weeks. <b>Results:</b> After total 16 sessions therapy using 670-nm diode administered within 4-week...
Chronic skin ulcers still represent a therapeutic challenge in dermatology. Among the various non‐invasive treatment modalities used for improvement of impaired wound healing, low‐intensity laser irradiations are gaining an increasing body interest. We delivered by 30 mW helium‐neon at energy density J/cm 2 three times weekly induction healing diverse causes. Twenty patients with same number ulcers, which had previously been treated conventional care median period 34 weeks (range: 3–120...
Gastric neuroendocrine (or gastric carcinoid) tumors have recently been classified into 3 types that differ in biological behavior and prognosis. Although the necessity of type-adapted treatment is widely accepted, it seems inconsistently used daily practice.Diagnostic differentiation various necessary for an adequate tumors.Retrospective study.University hospital department surgery.Twenty-seven patients with a histologically verified tumor.A univariate analysis survival rates respect to...
Abstract Background The potential for a fibrin sealant patch to reduce the risk of postoperative pancreatic fistula (POPF) remains uncertain. aim this study was evaluate whether is able POPF in patients undergoing pancreatoduodenectomy with pancreatojejunostomy. Methods In multicentre trial, were randomized receive either (patch group) or no (control group), and stratified by gland texture, duct size neoadjuvant treatment. primary endpoint POPF. Secondary endpoints included complications,...
Objective: To investigate the oncological outcomes of patients with pancreatic ductal adenocarcinoma (PDAC) who had an R 0 or 1 resection based on revised status (1 mm) after neoadjuvant therapy (NAT). Background: The is independent prognostic factor in upfront-resected PDAC; however, significance mm margin clearance NAT remains controversial. Methods: Patients undergoing pancreatectomy for PDAC were identified from 2 prospectively maintained databases. Clinicopathological and survival data...