A5053907593- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Diverticular Disease and Complications
- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal and Anal Carcinomas
- Hernia repair and management
- Urinary Bladder and Prostate Research
- Clinical Nutrition and Gastroenterology
- Inflammatory Bowel Disease
- Pancreatitis Pathology and Treatment
- Parathyroid Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Diagnosis and Treatment of Venous Diseases
- Pelvic and Acetabular Injuries
- Bariatric Surgery and Outcomes
- Abdominal Surgery and Complications
- Appendicitis Diagnosis and Management
- Aortic aneurysm repair treatments
- Cardiovascular Health and Disease Prevention
- Organ Transplantation Techniques and Outcomes
- Pancreatic and Hepatic Oncology Research
- Diet and metabolism studies
- COVID-19 and healthcare impacts
- Global Health and Surgery
Medical University of Vienna
2020-2025
Vienna General Hospital
2024
Royal College of Surgeons in Ireland
2022
Maastricht University Medical Centre
2022
Countess of Chester Hospital
2022
University of Liverpool
2022
Cleveland Clinic Florida
2022
Abstract Background Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment left-sided emergencies. We aim to evaluate surgical options globally used treat patients with acute emergencies factors that leading choice treatment, comparing HP RPA. Methods This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 who required surgery were included from 204 centers during...
Abstract Background Rectocele and intussusception are frequently observed during defecography as potential contributors to obstructed defecation syndrome (ODS). We aimed describe our initial experience with transanal minimally invasive surgery (TAMIS) mucosectomy muscular plication, a novel surgical approach treat patients ODS. Methods Conducted between August 2021 October 2023 at the Medical University of Vienna, 11 (8 female) were prospectively enrolled underwent TAMIS circular...
Introduction Postoperative pancreatic fistula (POPF) is the most frequent complication after partial pancreatectomy, which by definition associated with clinical consequences requiring changes in postoperative management. Despite numerous scientific efforts, effective procedures to prevent POPF are lacking. Obsidian ASG autologous platelet-rich fibrin matrix has been effectively applied anastomotic leakage following colorectal surgery. This study first investigate feasibility of using...
Summary Background The use of mesenchymal stem cells is considered a novel and promising therapeutic option for patients with perianal fistulizing Crohn’s disease; however, data on its clinical application remain scarce. This multicenter nationwide study aimed to assess the efficacy in closing complex anal fistulas. Methods In this 14 disease (3 males, 11 females) fistulas treated 3 tertiary hospitals Austria were included between October 2018 April 2021. Injection 120 million allogeneic...
The short bowel syndrome with intestinal failure (SBS-IF) is a rare but devastating medical condition. An absolute loss of length forces the patients into parenteral support (PS) dependency and variety sequalae resulting in increased morbidity mortality. Interdisciplinary treatment may include therapy effective, expensive intestinotrophic peptide teduglutide. A time-discrete Markov-model was developed to simulate effect (lifetime-costs, quality-adjusted life-years (QALYs) (LYs)) teduglutide...
The glucagon-like peptide 2 analogue teduglutide is an effective drug for the treatment of short bowel syndrome patients with intestinal failure (SBS-IF). This intestinotrophic improves capacity fluid and nutrient absorption through induction mucosal growth reduction gastrointestinal motility. Clinical trials demonstrated efficacy in reducing need parenteral support (PS). study describes SBS-IF patient population receiving therapy a specialized medical care setting.A retrospective analysis...
Abstract Background Sphincter-preserving techniques like autologous compound platelet-rich fibrin foam have gained popularity, offering potential for better functional outcomes in anal fistula treatment. The present study aimed to evaluate the efficacy and safety of Obsidian RFT ® . Methods conducted a retrospective analysis from January 2018 December 2022 on patients who received closure with RTF at Department General Surgery, Medical University Vienna. Clinical diagnosis, complemented by...
(1) Background: The Sphinkeeper implantation for faecal incontinence (FI) is a novel surgical procedure with limited data on its clinical efficacy. Therefore, we aimed to assess the functional outcome following surgery in patients refractory FI. (2) Methods: Between 2018 and 2020, eleven consecutive (9 female) FI met inclusion criteria were enrolled surgery. Functional quality of life evaluated by standard questionnaires pre- post-surgery. Migration protheses was demonstrated 3D endoanal...
Abstract Vascular bypass surgery in children differs significantly from adults. It is a rarely performed procedure the setting of trauma and tumor surgery. Besides technical challenges to reconstruct small spastic vessels, another concern grafting adequate limb length growth over time. The primary aim this study was assess long-term outcome after pediatric grafting, single academic center, focusing on potential effects development. In retrospective cohort analyses we included all patients...
Key Clinical Message Amyloidosis is a heterogeneous disease characterized by tissue deposition of abnormally folded fibrillary proteins that can manifest itself wide variety symptoms depending on the affected organs. GI involvement among amyloidosis patients common. Its clinical manifestation often presents with nonspecific such as weight loss, diarrhea, and malabsorption. With no specific treatment existing for amyloidosis, therapy focuses impeding amyloid managing patients' supportive...
The Sphinkeeper® procedure for treating faecal incontinence (FI) may be associated with potential implant migration (IM) and dislocation (ID), considerable variations regarding their occurrence effects on consecutive functional outcome. This study assessed IM ID following the its correlation physical activity. was a prospective observational clinical of ten patients undergoing operation due to FI between August 2020 November at Medical University Vienna. Patients were followed-up after 1, 2,...
Abstract Background Sacral neuromodulation (SNM) is a common treatment for patients with urinary and faecal incontinence. A close contact of the tined lead electrode targeted nerve likely to improve functional outcome. The aim this study was compare position SNM in relation sacral by comparing different implantation techniques. Methods This cadaver conducted at Division Anatomy Vienna's Medical University October 2020. We dissected 10 cadavers after bilateral ( n = 20), using two...
Sacral neuromodulation (SNM) is a widely accepted treatment for pelvic floor disorders, including constipation and fecal incontinence (FI). In 2017, standardized electrode placement method, the H technique, was introduced to minimize failure rates improve clinical outcomes. We aimed investigate technical feasibility functional outcome of procedure.In this prospective study, we evaluated first 50 patients who underwent SNM according technique between 2017 2020 at tertiary care hospital....
Fecal incontinence is a distressing condition characterized by the involuntary loss of solid and liquid stool gas, It affects significant proportion general population, with reported prevalence ranging from 1% to 20%. Despite its considerable impact on quality life, therapeutic options for fecal remain limited. Current treatment modalities include conservative approaches such as dietary modifications, pelvic floor exercises, pharmacotherapy. Surgical interventions, including sphincteroplasty...
Abstract Purpose The efficacy of the novel SphinKeeper® procedure for treatment fecal incontinence (FI) is not yet well defined. This study aimed to assess long-term functional outcomes after surgery. Methods We included 32 patients with FI (28 female), who were operated at a tertiary referral center between August 2018 and September 2021. Functional outcome quality life evaluated prospectively using validated questionnaires before Additionally, endoanal ultrasound anal manometry conducted...
Zusammenfassung Das obstruktive Defäkationssyndrom (ODS) ist eine Form der Verstopfung, die mit einer Stuhlentleerungsstörung verbunden ist. Krankheitsbild noch nicht vollständig verstanden, dementsprechend Evidenz zur Pathogenese und Therapie limitiert. Prinzipiell werden funktionelle Ursachen, wie Anismus oder das Puborektalissyndrom, von anatomischen Ursachen unterschieden. Häufige mechanische Hindernisse sind Rektozele Intussuszeption, zu erschwerten Defäkation führen können. Zur Auswahl...
Aim: There is currently an urgent need to identify factors beyond microsatellite instability, predictive of immunogenicity in colorectal cancer (CRC).Emerging evidence has pointed towards the important role members microbiome modulating immune milieu (1).Mucinous CRC a distinct histological subtype CRC, associated with poor response chemotherapy (2, 3).Fusobacterium nucleatum (F.nucleatum) commensal organism implicated non-mucinous pathogenesis (4, 5).Recent suggested F. may be especially...
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