- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Transplantation: Methods and Outcomes
- Hepatitis C virus research
- Pediatric Hepatobiliary Diseases and Treatments
- Abdominal vascular conditions and treatments
- Electrolyte and hormonal disorders
- Organ Donation and Transplantation
- Renal function and acid-base balance
- Parathyroid Disorders and Treatments
- Potassium and Related Disorders
- Colorectal Cancer Treatments and Studies
- Viral-associated cancers and disorders
- Abdominal Trauma and Injuries
- Parasitic infections in humans and animals
- Vascular anomalies and interventions
- Hepatitis B Virus Studies
- Pancreatitis Pathology and Treatment
- Surgical Simulation and Training
Hospital de Cruces
2015-2024
University of the Basque Country
2014-2023
BioCruces Health research Institute
2019-2023
Pontificia Universidad Católica de Chile
1998-2020
Fundación Chile
2020
Organización Nacional de Trasplantes
2019
Sociedad de Biología de Chile
2014-2016
Hospital Universitario Insular de Gran Canaria
2005
Instituto Cajal
2004
Hospital Universitario Virgen del Rocío
2004
To assess the real utility of orthotopic liver transplantation (OLT) in patients with cholangiocarcinoma, we need series large numbers cases and long follow-ups. The aim this paper is to review Spanish experience OLT for hilar peripheral cholangiocarcinoma try identify prognostic factors that could influence survival.Palliative treatment nondisseminated irresectable carries a zero 5-year survival rate. role these controversial, due fact rate lower than other indications lack organs.We...
Early allograft dysfunction (EAD) dramatically influences graft and patient outcomes. A lack of consensus on an EAD definition hinders comparisons liver transplant outcomes management recipients among within centers. We sought to develop a model for the quantitative assessment early function [Model Allograft Function Scoring (MEAF)] after transplantation. retrospective study including 1026 consecutive transplants was performed MEAF score development. Multivariate data analysis used select...
Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim this project was to provide a practical framework for care metastases, focus on terminology, diagnosis, management.This multiorganizational, multidisciplinary consensus. consensus group produced statements which focused management. Statements were refined during an online Delphi process, those 70 per cent agreement or above reviewed at final meeting. Iterations the report shared by...
Controlled donation after circulatory death (cDCD) has been associated with a high incidence of ischemic cholangiopathy and other perioperative complications. In an attempt to avoid these complications, we implemented active protocol cDCD liver transplant (LT) normothermic regional perfusion (NRP) preservation.This is descriptive analysis data collected from prospective date base LT preserved NRP January 2015 June 2017 minimum follow up 9 months.Fifty-seven potential donors were connected...
Abstract Background Bile duct injury (BDI) after cholecystectomy is a serious complication. In small subset of patients with BDI, failure surgical or non-surgical management might lead to acute chronic liver failure. The aim this study was review the indications and outcome transplantation (LT) for BDI open laparoscopic cholecystectomy. Methods Patients who were on waiting list LT between January 1987 December 2010 identified from centres in Spain. A standardized questionnaire sent each unit...
Although good results have been reported with the use of normothermic regional perfusion (NRP) in controlled donation after circulatory death (cDCD) liver transplantation (LT), there is a lack evidence to demonstrate similar brain (DBD). We present single-center retrospective case-matched (1:2) study including 100 NRP cDCD LTs and 200 DBD median follow-up 36 months. Matching was done according donor age, recipient Model for End-Stage Liver Disease score, cold ischemia time. The following...
Tacrolimus, a cornerstone immunosuppressant, is available as twice-daily formulation (tacrolimus bid). A once-daily prolonged-release qd) has been developed. This 6-week, randomized, phase 2, multicenter, open-label, prospective trial in primary liver transplant recipients investigated and compared the pharmacokinetics (PK) of tacrolimus for qd bid formulations. All patients received tacrolimus-based immunosuppression qd, n = 67; bid, 62). PK data were 77 45; 32). Tacrolimus area under curve...
Journal Article Recurrence patterns and post-recurrence survival of patients with bilobar colorectal liver metastases: international multicentre retrospective study Get access Bilobar CRC Liver Metastases Research Collaborative Search for other works by this author on: Oxford Academic Google Scholar British Surgery, Volume 112, Issue 3, March 2025, znaf003, https://doi.org/10.1093/bjs/znaf003 Published: 04 2025 history Received: 19 2024 Revision received: 24 September Accepted: 03 January
The impact of human immunodeficiency virus (HIV) infection on patients undergoing liver transplantation (LT) for hepatocellular carcinoma (HCC) is uncertain. This study aimed to assess the outcome a prospective Spanish nationwide cohort HIV-infected LT HCC (2002-2014). These were matched (age, gender, year LT, center, and hepatitis C (HCV) or B infection) with non-HIV-infected controls (1:3 ratio). Patients incidental excluded. Seventy-four 222 included. All had cirrhosis, mostly due HCV...
To assess health-related quality of life (HRQoL) in patients following liver transplantation and the factors associated with HRQoL variation.Sociodemographic clinical data were collected for 60 consecutive activated a single hospital. Patients classified according to severity cirrhosis (Child-Pugh class) disease etiology (alcoholic cirrhosis, viral cholestatic diseases, hepatocarcinoma). was assessed by three different questionnaires: Health Survey Short Form 36 (SF-36), Hospital Anxiety...
Background Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim this project was to provide a practical framework for care focus on terminology, diagnosis management. Methods This multi-organisational, multidisciplinary consensus. consensus group produced statements which focused Statements were refined during an online Delphi process those 70% agreement or above reviewed at final meeting. Iterations the report shared by electronic...
Case Reports| November 15 2002 Encephalitis Caused by Human Herpesvirus-6 in a Liver Transplant Recipient Subject Area: Neurology and Neuroscience Miguel Montejo; Montejo aDivisions of Infectious Diseases, Search for other works this author on: This Site PubMed Google Scholar Jose Ramon Fernandez; Fernandez bHepatology, Milagros Testillano; Testillano Andres Valdivieso; Valdivieso cLiver Transplantation Surgery, Koldo Aguirrebengoa; Aguirrebengoa Carmen Varas; Varas dDermatology Service,...
The once‐daily prolonged‐release formulation of tacrolimus has been recently related with significant graft and patient mid‐term survival advantages; however, practical information on the de novo administration after liver transplantation longterm outcomes is currently lacking. This study a 5‐year retrospective analysis single‐center cohort transplant recipients treated (April 2008/August 2011). consisted 160 patients, including 23 pretransplant renal dysfunction, median follow‐up 57.6...