A5025369403- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Donation and Transplantation
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Appendicitis Diagnosis and Management
- COVID-19 and healthcare impacts
- Transplantation: Methods and Outcomes
- Renal and Vascular Pathologies
- Liver Disease Diagnosis and Treatment
- Renal cell carcinoma treatment
- Biliary and Gastrointestinal Fistulas
- Pancreatic function and diabetes
- Pancreatitis Pathology and Treatment
- Abdominal vascular conditions and treatments
- Polyomavirus and related diseases
- Hernia repair and management
- Renal Diseases and Glomerulopathies
- Adrenal and Paraganglionic Tumors
- Intraperitoneal and Appendiceal Malignancies
- Cancer Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
BioCruces Health research Institute
2020-2025
University of the Basque Country
2014-2025
Hospital de Cruces
2016-2025
The University of Texas Health Science Center at Tyler
2024
Ospedale Vincenzo Cervello
2022
People's Liberation Army No. 150 Hospital
2022
Chinese People's Liberation Army
2022
AdventHealth Tampa
2022
Asan Medical Center
2022
University of Ulsan
2022
Laparoscopic and robotic techniques have both been well adopted as safe options in selected patients undergoing hepatectomy. However, it is unknown whether either approach superior, especially for major hepatectomy such right or extended (RH/ERH).To compare the outcomes of vs laparoscopic RH/ERH.In this case-control study, propensity score matching analysis was performed to minimize selection bias. Patients RH/EHR at 29 international centers from 2008 2020 were included.Robotic RH/ERH.Data...
Background. Sirolimus has been associated with an increased risk of wound-healing complications in several retrospective analyses. The authors compared the rates renal allograft recipients a prospective, randomized trial sirolimus-mycophenolate mofetil-prednisone versus tacrolimus-mycophenolate mofetil-prednisone. Methods. All patients received antithymocyte globulin induction. In first phase study, (n=77) were included regardless body mass index (BMI). second (n=46 patients), excluded BMI...
Calcineurin inhibitors have decreased acute rejection and improved early renal allograft survival, but their use has been implicated in the development of chronic nephrotoxicity. We performed a prospective, randomized trial kidney transplantation comparing sirolimus-MMF-prednisone to tacrolimus-MMF-prednisone. Eighty-one patients sirolimus group 84 tacrolimus were enrolled (mean follow-up = 33 months; range 13-47 months). At 1 year, patient survival was similar groups (98% with sirolimus,...
We previously proposed a quantitative approach to assess donor organs for cadaver renal transplantation. To improve on our original scoring system, we studied 34 324 patients who received transplants from adult donors between 1994 and 1999 were reported the UNOS Scientific Renal Transplant Registry. A system was developed five variables (age, 0-25 points; history of hypertension, 0-4; creatinine clearance before procurement, cause death, 0-3; HLA mismatch, 0-3) that showed significant...
Pancreas allograft rejection in dogs with pancreaticocystostomy can be predicted advance of hyperglycemia by monitoring the urinary amylase (UA) concentration (U/L): In initial experiments, UA values declined to less than 1000 1.3 +/- 0.2 days before nonimmunosuppressed dogs, 3.3 1.0 treated cyclosporine (CsA), and 9.3 0.7 CsA, azathioprine (Aza), prednisone (triple therapy). Autotransplanted control maintained high urine concentrations indefinitely (mean 125,544 36,931). a subsequent...
Abstract Background Minimally invasive right posterior sectionectomy (RPS) is a technically challenging procedure. This study was designed to determine outcomes following robotic RPS (R-RPS) and laparoscopic (L-RPS). Methods An international multicentre retrospective analysis of patients undergoing R-RPS versus those who had purely L-RPS at 21 centres from 2010 2019 performed. Patient demographics, perioperative parameters, postoperative were analysed retrospectively central database....
To compare the outcomes between robotic major hepatectomy (R-MH) and laparoscopic (L-MH).Robotic techniques may overcome limitations of liver resection. However, it is unknown whether R-MH superior to L-MH.This a post hoc analysis multicenter database patients undergoing or L-MH at 59 international centers from 2008 2021. Data on patient demographics, center experience volume, perioperative outcomes, tumor characteristics were collected analyzed. Both 1:1 propensity-score matched (PSM)...
The relationship of kidney function and CKD risk factors to structural changes in the renal parenchyma normal adults is unclear. This study assessed whether nephron hypertrophy nephrosclerosis had similar or different associations with factors.From 1999 2009, 1395 living donors a core needle biopsy their donated during transplant surgery. mean nonsclerotic glomerular volume density (globally sclerotic nonsclerotic) were estimated using Weibel Gomez stereologic methods. All tubules counted 1...
Controlled donation after circulatory death (cDCD) has been associated with a high incidence of ischemic cholangiopathy and other perioperative complications. In an attempt to avoid these complications, we implemented active protocol cDCD liver transplant (LT) normothermic regional perfusion (NRP) preservation.This is descriptive analysis data collected from prospective date base LT preserved NRP January 2015 June 2017 minimum follow up 9 months.Fifty-seven potential donors were connected...
Abstract Background Limited liver resections (LLRs) for tumours located in the posterosuperior segments of are technically demanding procedures. This study compared outcomes robotic (R) and laparoscopic (L) LLR (IV, VII, VIII). Methods was an international multicentre retrospective analysis patients who underwent R-LLR or L-LLR at 24 centres between 2010 2019. Patient demographics, perioperative parameters, postoperative were analysed; 1 : 3 propensity score matching (PSM) coarsened exact...
Background. Subclinical rejection, defined as histologic acute rejection in the absence of graft dysfunction, has been suggested a cause chronic allograft rejection. In cyclosporine-treated patients, incidence subclinical 3 months after transplant is reported to be approximately 30%. The intent our study was determine tacrolimus-treated renal recipients. Methods. We prospectively studied on surveillance biopsies performed transplantation 114 patients transplanted between September 1, 1998...
The purpose of this study was to characterize the histology antibody-mediated rejection (AMR) in ABO blood-group-incompatible (ABOI) kidney transplants as well on protocol biopsies performed at time stable allograft function. Between 5/99 and 1/02, we 32 ABOI (13 A2, 19 non-A2 blood-group living donors). Nineteen were for dysfunction, 127 0, 3, 7, 14, 28 days 3 12 months post transplant. Twenty-five patients have functioning allografts (mean 585 transplant). Nine (28%) developed clinical...
Background. The deceased donor score (DDS), expanded criteria (ECD) definition, and resistive index (RI) were developed for pretransplant evaluation of donors. DDS ECD are determined by a calculation risk from variables, while RI is flow characteristics kidneys during machine preservation (MP). This study was designed to compare DDS, status, as predictors outcome after transplantation. We also interested see if or could identify most likely benefit MP. Methods. retrospectively reviewed...
Avoiding donor-specific antibody (DSA) is difficult for sensitized patients. Improved understanding of the risk low level DSA needed.We retrospectively compared outcomes 954 patients transplanted with varied levels baseline detected by single antigen beads and B flow cytometric crossmatch (XM). Patients were grouped as follows: -DSA/-XM, +DSA/-XM, +DSA/low +XM, +DSA/high -DSA/+XM followed up a mean 4.1 ± 1.9 years (similar among groups, P = 0.49).Death-censored allograft survival was similar...
Although good results have been reported with the use of normothermic regional perfusion (NRP) in controlled donation after circulatory death (cDCD) liver transplantation (LT), there is a lack evidence to demonstrate similar brain (DBD). We present single-center retrospective case-matched (1:2) study including 100 NRP cDCD LTs and 200 DBD median follow-up 36 months. Matching was done according donor age, recipient Model for End-Stage Liver Disease score, cold ischemia time. The following...
Both robotic and laparoscopic right anterior sectionectomy central hepatectomy can be performed safely in expert centres, with excellent outcomes. The approach was associated statistically significant less blood loss compared laparoscopy, although the clinical relevance of this finding remains unclear.