Alexander Waldthaler

ORCID: 0000-0003-3299-1729
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About
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Research Areas
  • Pancreatitis Pathology and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Gallbladder and Bile Duct Disorders
  • Liver Disease Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Gastrointestinal disorders and treatments
  • Diabetes and associated disorders
  • Neuroendocrine Tumor Research Advances
  • Pediatric Hepatobiliary Diseases and Treatments
  • Therapeutic Uses of Natural Elements
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Vitamin K Research Studies
  • Bariatric Surgery and Outcomes
  • Transplantation: Methods and Outcomes
  • Building energy efficiency and sustainability
  • Hedgehog Signaling Pathway Studies
  • Intestinal Malrotation and Obstruction Disorders
  • Gastroesophageal reflux and treatments
  • Body Contouring and Surgery
  • Oral and Maxillofacial Pathology
  • Dermatological and COVID-19 studies
  • Colorectal Cancer Screening and Detection
  • Fungal Infections and Studies
  • Liver Diseases and Immunity
  • Biliary and Gastrointestinal Fistulas

Karolinska Institutet
2019-2024

Karolinska University Hospital
2019-2024

European Centre for Disease Prevention and Control
2021

University Hospital Regensburg
2015-2018

Otto-von-Guericke University Magdeburg
2010-2013

Background: Patients with chronic pancreatitis (CP) have an increased risk of developing pancreatic ductal adenocarcinoma (PDAC). We present data on PDAC in one the most extensive European single-centre cohort studies patients CP. Methods: Retrospective analysis prospectively collected CP was performed. Aetiology determined according to M-ANNHEIM classification system and only definite > 18 years at were included. The final dataset included 581 diagnosed between 2003 2018. Results: At...

10.3390/jcm9113720 article EN Journal of Clinical Medicine 2020-11-19

Background: Osteopathy is common in patients with chronic pancreatitis (CP), but previous studies carry several limitations. Vitamin K essential for bone metabolism, its role this setting has never been investigated. Our aim to assess the prevalence of osteoporosis and osteopenia CP patients, investigate association between osteopathy features nutritional parameters, especially vitamin D levels. Methods: Multicentre cross-sectional study on diagnosed according M-ANNHEIM criteria. Bone...

10.1038/s41424-018-0066-8 article EN cc-by-nc-nd Clinical and Translational Gastroenterology 2018-10-01
Florence E.M. de Rijk Charlotte L. van Veldhuisen Marc G. Besselink Jeanin E. van Hooft Hjalmar C. van Santvoort and 95 more Erwin J. M. van Geenen Péter Hegyi Matthias Löhr J. Enrique Domínguez‐Muñoz Pieter Jan F. de Jonge Marco J. Bruno Robert C. Verdonk Massimo Falconi Wen‐Bin Zou Trond Engjom Chee Y. Ooi Robert Sutton Luca Frulloni John P. Neoptolemos C. Mel Wilcox Vujasinovic Miroslav Guru Trikudanathan Zhuan Liao Truls Hauge Joachim Mössner Chantal Hoge Paul Fockens J. Sven D. Mieog Gabriele Capurso Yunfeng Cui Enrique de‐Madaria Marius Distler Ali A. Aghdassi David C. Whitcomb Kylie Russell Georg Beyer Lumír Kunovsky Wilhelmus J. Kwanten Andrea Nava Kevin C. Conlon Ajith K. Siriwardena Salvatore Paiella Felipe Alconchel Marco V. Marino Vincent E. de Meijer Carlos Domingo del Pozo Jörg Kleeff Aarti Lakshmanan Michael Jen Lie Chu Stefan A.W. Bouwense Pueya Rashid Nashidengo Perivoliotis Konstantinos Edoardo Maria Muttillo İbrahim Umar Garzali Maria Jesús Castro Santiago Víctor López‐López Francesco Torri Moritz Schmelzle Povilas Ignatavičius Dennis A. Wicherts António Gomes Nikolaos Machairas Panagiotis Dorovinis Alejandro Serrablo Kjetil Søreide Mohammad Rahbari Michael J. J. Chu Margarita Ptašņuka Marius Petrulionis Colin Noel Ernesto Castro Marcello Di Martino Alfonso Recordare Stefan Stättner Fabio Ausania V. Hartman Geert Roeyen V. Egorov Tomas Vanagas Mohamed Ebrahim Elena Arabadzhieva Giuseppe Malleo Liang Li David H. Adams Grzegorz Oracz Reddy D. Nageshwar Alexander Waldthaler Atsushi Masamune Asbjørn Mohr Drewes Antonio Amodio Temel Tirkes Anshu Srivastava Gregory J. Beilman Zoltán Berger Björn Lindkvist Giulia Martina Cavestro Cheryl E. Gariepy László Czakó Milena Di Leo Vishal Sharma

Despite evidence-based guidelines, exocrine pancreatic insufficiency is frequently underdiagnosed and undertreated in patients with chronic pancreatitis. Therefore, the aim of this study to provide insight into current opinion clinical decision-making international pancreatologists regarding management insufficiency. An online survey case vignette was sent experts pancreatitis members various associations: EPC, E-AHPBA DPSG. Experts were selected based on publication record from past 5...

10.1016/j.pan.2022.03.013 article EN cc-by Pancreatology 2022-03-16

Background Paraduodenal pancreatitis (PDP) is a particular form of chronic (CP) occurring in and around the duodenal wall. Despite its low prevalence, this rare condition presents significant challenge clinical practice.Methods We retrospectively analysed electronic medical charts all patients with diagnosis identified those PDP, between January 1999 December 2020.Results There were 35 diagnosed PDP (86% males 14% females); median age 56 ± 11 (range 38–80). Alcohol overconsumption was...

10.1080/00365521.2022.2036806 article EN Scandinavian Journal of Gastroenterology 2022-02-09

Insertion of a self-expandable metal stent is still controversial for treatment benign common bile duct stenosis but can be valuable alternative to surgical treatment.Aim our study was analyze the efficacy covered and uncovered in patients with chronic pancreatitis stenosis.Twenty due alcoholic were retrospective analyzed. All had advanced pancreatitis, presenting calcifications pancreatic head. Uncovered (uSEMS) used 11 (3 females, 8 males) while 9 6 partially (cSEMS) inserted. treated...

10.6092/1590-8577/870 article EN PubMed 2013-01-10

Ultrasonically guided fine-needle aspirations were done in the liver of 42 cases malignancy established later by autopsy and biopsy. The sensitivity was 95.3%. Only one case, a metastasis renal carcinoma, precise tumour classification not possible cytologically. Pancreatic malignancies biopsied 28 with verified diagnoses at post mortem biopsy; 85.7%. One pancreatic head adenocarcinoma In 16 gastrointestinal carcinoma operation 93.8%. cirrhotic gastric only insufficient cytological material...

10.1055/s-2008-1069774 article EN DMW - Deutsche Medizinische Wochenschrift 2008-03-26

Background: Chronic pancreatitis is a long-standing, inflammatory condition of the pancreas that leads to progressive damage and loss function pancreatic parenchyma development possible locoregional systemic medical complications. Materials methods: In this review, we tried summarize current evidence on non-surgical treatment trying suggest practical approach management chronic pancreatitis. Results: Besides unclear pathophysiological mechanism poorly unknown epidemiology, complex syndrome...

10.1177/1457496920905559 article EN Scandinavian Journal of Surgery 2020-03-01

Abstract Background and study aims Conventional endoscopic retrograde cholangiopancreatography (ERCP) is hampered by two-dimensional visualization, post-procedural adverse events (AEs), exposure to ionizing radiation. Bimodal ERCP might mitigate these challenges, but no reports of its use are available date. The aim this was explore the feasibility bimodal ERCP, while investigating potential clinical yield. Patients methods This a retrospective observational patients that underwent in single...

10.1055/a-1070-8749 article EN cc-by-nc-nd Endoscopy International Open 2020-02-21

Aims The management of Mirizzi syndrome has been primarily surgical, ranging from cholecystectomy to en bloc resection with hepatico-jejunostomy for advanced Csendes III and IV types. introduction digital single-operator cholangioscopy (dSOC) allows ductal clearance in patients syndrome. Although small series have highlighted the feasibility an endoscopic approach, there is a lack comprehensive comparisons between surgical treatments. objective current study compare outcomes safety...

10.1055/s-0044-1782885 article EN Endoscopy 2024-04-01

Abstract Malignant gastric outlet obstruction (GOO) occurs often late during disseminated disease, requiring palliation. Placement of duodenal self-expandable metal stents (SEMS) is a common method for relieving malignant GOO but recurrent common, warranting reintervention. The aim the present study was to identify predictive factors stent patency at 3 months and survival. Also, rate adverse events after stenting were analyzed. This retrospective observational single-center including all...

10.1055/a-2487-2722 article EN cc-by-nc-nd Endoscopy International Open 2024-11-25
Marcus Hollenbach Christian Heise Einas Abou-Ali Aistė Gulla Francesco Auriemma and 94 more Kevin C. Soares Galen Leung Mark Schattner William R. Jarnagin Tiegong Wang Fabrice Caillol Marc Giovannini Yanis Dahel Thilo Hackert Woo Hyun Paik Alessandro Zerbi Gennaro Nappo Bertrand Napoléon Urban Arnelo Erik Haraldsson Asif Halimi Alexander Waldthaler Uwe Will Rita Saadeh Viliam Masaryk Sophia E. van der Wiel Marco J. Bruno Enrique Pérez‐Cuadrado‐Robles Pierre H. Deprez Alain Sauvanet Louisa Bolm Tobias Keck Régis Souche Jean-Michel Fabre Nicolas Musquer Georg Kähler Steffen Seyfried Maria Chiara Petrone Alberto Mariani Piera Zaccari Giulio Belfiori Stefano Crippa Massimo Falconi Stefano Partelli Bengi Su Yilmaz İhsan Ekin Demir Güralp O. Ceyhan Sohei Satoi J.-M. Régimbeau Johan Gagnière Alessandro Repici Andrea Anderloni Charles M. Vollmer Fabio Casciani Marco Del Chiaro Atsushi Oba Richard D. Schulick Arthur Berger Laura Maggino Roberto Salvia Peter Schemmer D Wichmann Yosuke Inoue Mário Dinis‐Ribeiro Ana Laranjo Diogo Libânio Tobias Kleemann Vasile Șandru M Ilie Reea Ahola Johanna Laukkarinen Brigitte Schumacher David J. Albers Tiago Cúrdia Gonçalves Louise Barbier Ephrem Salamé Tobias J. Weismüller Dominik Heling Arnaud Alvès Elias Karam Nicolas Régenet Ana Dugic Steffen Muehldorfer Stéphanie Truant Karel Caca Benjamin Meier Bogdan Miuțescu Marcel Tanţău David Jérémie Birnbaum Rainer Christoph Miksch Edris Wedi Katrin Salzmann Matthieu Bruzzi Renato Micelli Lupinacci P. David Charles de Ponthaud Arthur Schmidt Sara Regnér Sébastien Gaujoux

Objective Ampullary neoplastic lesions can be resected by endoscopic papillectomy (EP) or transduodenal surgical ampullectomy (TSA) while pancreaticoduodenectomy is reserved for more advanced lesions. We present the largest retrospective comparative study analysing EP and TSA. Design Of all patients in database, with prior interventions, benign histology malignancy (T2 more), hereditary syndromes those undergoing pancreatoduodenectomy were excluded. All remaining cases as well a subgroup of...

10.1136/gutjnl-2022-327996 article EN Gut 2024-12-06

Abstract Background: The duration of an endoscopic retrograde cholangiopancreatography (ERCP) is influenced by a multitude factors. aim this study was to describe the factors influencing ERCP time and create tool for preintervention estimation time. Methods: Data from 74 248 ERCPs performed 2010 2019 were extracted Swedish National Quality Registry (GallRiks) identify variables predictive using linear regression analyses root mean squared error (RMSE) as loss function. Ten combined duration....

10.1055/a-2371-1367 article EN Endoscopy 2024-08-07

Introduction Although abdominal pain is the most prevalent and disabling symptom in patients with chronic pancreatitis (CP), there are also who have painless CP.Patients methods We performed a retrospective analysis of diagnosis CP. A total 279 definite CP completed demographic clinical data were included final analysis.Results There 75 (26.9%) These had significantly higher mean age at diagnosis, 61.7 years, than 52.5 years (p < 0.001). Painless painful similar rates diabetes mellitus (DM)...

10.1080/00365521.2022.2137692 article EN Scandinavian Journal of Gastroenterology 2022-10-27
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