- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Diabetes and associated disorders
- Neuroendocrine Tumor Research Advances
- Pediatric Hepatobiliary Diseases and Treatments
- Therapeutic Uses of Natural Elements
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Vitamin K Research Studies
- Bariatric Surgery and Outcomes
- Transplantation: Methods and Outcomes
- Building energy efficiency and sustainability
- Hedgehog Signaling Pathway Studies
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Body Contouring and Surgery
- Oral and Maxillofacial Pathology
- Dermatological and COVID-19 studies
- Colorectal Cancer Screening and Detection
- Fungal Infections and Studies
- Liver Diseases and Immunity
- Biliary and Gastrointestinal Fistulas
Karolinska Institutet
2019-2024
Karolinska University Hospital
2019-2024
European Centre for Disease Prevention and Control
2021
University Hospital Regensburg
2015-2018
Otto-von-Guericke University Magdeburg
2010-2013
Background: Patients with chronic pancreatitis (CP) have an increased risk of developing pancreatic ductal adenocarcinoma (PDAC). We present data on PDAC in one the most extensive European single-centre cohort studies patients CP. Methods: Retrospective analysis prospectively collected CP was performed. Aetiology determined according to M-ANNHEIM classification system and only definite > 18 years at were included. The final dataset included 581 diagnosed between 2003 2018. Results: At...
Background: Osteopathy is common in patients with chronic pancreatitis (CP), but previous studies carry several limitations. Vitamin K essential for bone metabolism, its role this setting has never been investigated. Our aim to assess the prevalence of osteoporosis and osteopenia CP patients, investigate association between osteopathy features nutritional parameters, especially vitamin D levels. Methods: Multicentre cross-sectional study on diagnosed according M-ANNHEIM criteria. Bone...
Despite evidence-based guidelines, exocrine pancreatic insufficiency is frequently underdiagnosed and undertreated in patients with chronic pancreatitis. Therefore, the aim of this study to provide insight into current opinion clinical decision-making international pancreatologists regarding management insufficiency. An online survey case vignette was sent experts pancreatitis members various associations: EPC, E-AHPBA DPSG. Experts were selected based on publication record from past 5...
Background Paraduodenal pancreatitis (PDP) is a particular form of chronic (CP) occurring in and around the duodenal wall. Despite its low prevalence, this rare condition presents significant challenge clinical practice.Methods We retrospectively analysed electronic medical charts all patients with diagnosis identified those PDP, between January 1999 December 2020.Results There were 35 diagnosed PDP (86% males 14% females); median age 56 ± 11 (range 38–80). Alcohol overconsumption was...
Insertion of a self-expandable metal stent is still controversial for treatment benign common bile duct stenosis but can be valuable alternative to surgical treatment.Aim our study was analyze the efficacy covered and uncovered in patients with chronic pancreatitis stenosis.Twenty due alcoholic were retrospective analyzed. All had advanced pancreatitis, presenting calcifications pancreatic head. Uncovered (uSEMS) used 11 (3 females, 8 males) while 9 6 partially (cSEMS) inserted. treated...
Ultrasonically guided fine-needle aspirations were done in the liver of 42 cases malignancy established later by autopsy and biopsy. The sensitivity was 95.3%. Only one case, a metastasis renal carcinoma, precise tumour classification not possible cytologically. Pancreatic malignancies biopsied 28 with verified diagnoses at post mortem biopsy; 85.7%. One pancreatic head adenocarcinoma In 16 gastrointestinal carcinoma operation 93.8%. cirrhotic gastric only insufficient cytological material...
Background: Chronic pancreatitis is a long-standing, inflammatory condition of the pancreas that leads to progressive damage and loss function pancreatic parenchyma development possible locoregional systemic medical complications. Materials methods: In this review, we tried summarize current evidence on non-surgical treatment trying suggest practical approach management chronic pancreatitis. Results: Besides unclear pathophysiological mechanism poorly unknown epidemiology, complex syndrome...
Abstract Background and study aims Conventional endoscopic retrograde cholangiopancreatography (ERCP) is hampered by two-dimensional visualization, post-procedural adverse events (AEs), exposure to ionizing radiation. Bimodal ERCP might mitigate these challenges, but no reports of its use are available date. The aim this was explore the feasibility bimodal ERCP, while investigating potential clinical yield. Patients methods This a retrospective observational patients that underwent in single...
Aims The management of Mirizzi syndrome has been primarily surgical, ranging from cholecystectomy to en bloc resection with hepatico-jejunostomy for advanced Csendes III and IV types. introduction digital single-operator cholangioscopy (dSOC) allows ductal clearance in patients syndrome. Although small series have highlighted the feasibility an endoscopic approach, there is a lack comprehensive comparisons between surgical treatments. objective current study compare outcomes safety...
Abstract Malignant gastric outlet obstruction (GOO) occurs often late during disseminated disease, requiring palliation. Placement of duodenal self-expandable metal stents (SEMS) is a common method for relieving malignant GOO but recurrent common, warranting reintervention. The aim the present study was to identify predictive factors stent patency at 3 months and survival. Also, rate adverse events after stenting were analyzed. This retrospective observational single-center including all...
Objective Ampullary neoplastic lesions can be resected by endoscopic papillectomy (EP) or transduodenal surgical ampullectomy (TSA) while pancreaticoduodenectomy is reserved for more advanced lesions. We present the largest retrospective comparative study analysing EP and TSA. Design Of all patients in database, with prior interventions, benign histology malignancy (T2 more), hereditary syndromes those undergoing pancreatoduodenectomy were excluded. All remaining cases as well a subgroup of...
Abstract Background: The duration of an endoscopic retrograde cholangiopancreatography (ERCP) is influenced by a multitude factors. aim this study was to describe the factors influencing ERCP time and create tool for preintervention estimation time. Methods: Data from 74 248 ERCPs performed 2010 2019 were extracted Swedish National Quality Registry (GallRiks) identify variables predictive using linear regression analyses root mean squared error (RMSE) as loss function. Ten combined duration....
Introduction Although abdominal pain is the most prevalent and disabling symptom in patients with chronic pancreatitis (CP), there are also who have painless CP.Patients methods We performed a retrospective analysis of diagnosis CP. A total 279 definite CP completed demographic clinical data were included final analysis.Results There 75 (26.9%) These had significantly higher mean age at diagnosis, 61.7 years, than 52.5 years (p < 0.001). Painless painful similar rates diabetes mellitus (DM)...