A5024166980- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Infant Nutrition and Health
- Airway Management and Intubation Techniques
- Congenital Heart Disease Studies
- Respiratory viral infections research
- Child and Adolescent Health
- Pediatric Hepatobiliary Diseases and Treatments
- Birth, Development, and Health
- Gut microbiota and health
- Immunodeficiency and Autoimmune Disorders
- Mechanical Circulatory Support Devices
- Preterm Birth and Chorioamnionitis
- Children's Physical and Motor Development
- Hemoglobinopathies and Related Disorders
- Diabetes and associated disorders
- Family and Patient Care in Intensive Care Units
- Telomeres, Telomerase, and Senescence
- Pediatric health and respiratory diseases
- Cardiovascular Conditions and Treatments
- Parasitic infections in humans and animals
Karolinska University Hospital
2016-2025
Karolinska Institutet
2016-2025
Massachusetts Institute of Technology
2021
Ragon Institute of MGH, MIT and Harvard
2021
University of Virginia
2021
Science for Life Laboratory
2021
Máxima Medisch Centrum
2021
Radboud University Nijmegen
2021
Groote Schuur Hospital
2020
University of Cape Town
2020
Epidemiological data suggest that early life exposures are key determinants of immune-mediated disease later in life. Young children also particularly susceptible to infections, warranting more analyses immune system development Such mostly have been performed mouse models or human cord blood samples, but these cannot account for the complex environmental influencing newborns after birth. Here, we longitudinal 100 newborn children, sampled up 4 times during their first 3 months From μL...
Immune-microbe interactions early in life influence the risk of allergies, asthma, and other inflammatory diseases. Breastfeeding guides healthier immune-microbe relationships by providing nutrients to specialized microbes that turn benefit host's immune system. Such bacteria have co-evolved with humans but are now increasingly rare modern societies. Here we show a lack bifidobacteria, particular depletion genes required for human milk oligosaccharide (HMO) utilization from metagenome, is...
Recommendations for neonatologist performed echocardiography in Europe: Consensus Statement endorsed by European Society Paediatric Research (ESPR) and Neonatology (ESN)
Background: Approximately 10% of all births worldwide are preterm. Often these infants admitted at a Neonatal Intensive Care Unit (NICU). The NICU environment with periods unnatural light, noise and repeated disturbances is very stressful for to the NICU. In addition separation parents causes stress both infant parents. A way support include in care their Family-Centered (FCC). FCC an approach planning, delivery evaluation healthcare, based on partnership between healthcare professionals...
Increasing numbers of survivors preterm birth are growing into adulthood today. Long-term health-effects prematurity still poorly understood, but include increased risk for diabetes, obesity and cardiovascular diseases in adult life. To test if reduced physical fitness may be a link the causal chain later life, association exercise capacity was investigated. The hypothesis that contributes independently other factors to lower adulthood.Population-based national cohort study all males...
Abstract Aims The aim of this study was to examine the potential association family‐centred care as perceived by parents during a NICU stay with parents’ depressive symptoms at discharge and 4 months corrected for infant age. Design A longitudinal, multicentre cohort conducted from 2018 2020 in 23 NICUs across 15 countries. Methods Parents ( n = 635 mothers, 466, fathers) infants 739) born before 35 weeks gestation admitted participating were enrolled first their infants’ hospitalizations....
Abstract Preterm newborns are more likely to suffer from infectious diseases at birth compared children delivered term. Whether this is due compromised cellular, humoral, or organ-specific development remains unclear. To begin define whether maternal–fetal antibody transfer profiles differ across preterm (PT) and fullterm (FT) infants, the overall quantity functional quality of an array 24 vaccine-, endemic pathogen-, common antigen-specific antibodies were assessed a cohort 11 PT 12...
Importance Preventive efforts in pregnancy-related alloimmunization have considerably decreased the prevalence of hemolytic disease fetus and newborn (HDFN). International studies are therefore essential to obtain a deeper understanding postnatal management outcomes HDFN. Taken together with numerous treatment options, large practice variations among centers may exist. Objectives To assess HDFN international identify opportunities improve care. Design, Setting, Participants In this...
Abstract Background Training and assessment of operator competence for the less invasive surfactant administration (LISA) procedure vary. This study aimed to obtain international expert consensus on LISA training (LISA curriculum (LISA-CUR)) tool (LISA-AT)). Methods From February July 2022, an three-round Delphi process gathered opinions from experts (researchers, developers, clinical educators) a list items be included in LISA-CUR LISA-AT (Round 1). The rated importance each item 2). Items...
Parenteral nutrition-associated liver disease (PNALD) is frequently detected in neonatal intensive care units. lipid emulsion (PLE) content has been implicated its pathogenesis. We aimed to study the effect on incidence and outcome of PNALD by replacing soy-based PLE with olive oil-based a population-based group preterm infants.All infants Stockholm County gestational age (GA) <30 weeks were included (n = 615). Infants who died before 28 days or referred from other regions excluded 97). was...
<h3>Educational aims</h3> To understand the physiology of respiratory support immediately after birth learn current guidelines for neonatal resuscitation discuss noninvasive ventilation strategies in relation to development bronchopulmonary dysplasia <h3>Summary</h3> Bronchopulmonary (BPD) remains most common severe adverse pulmonary outcome preterm birth. Low gestational age and weight are strongest risk factors BPD, but pathogenesis is complex. The strategy during initial period may have a...