A5101965214- Respiratory viral infections research
- Virology and Viral Diseases
- HIV, Drug Use, Sexual Risk
- Influenza Virus Research Studies
- Viral Infections and Vectors
- HIV/AIDS Research and Interventions
- Bacterial Infections and Vaccines
- Adolescent Sexual and Reproductive Health
- Pneumonia and Respiratory Infections
- Hepatitis Viruses Studies and Epidemiology
- Vaccine Coverage and Hesitancy
- Syphilis Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Helicobacter pylori-related gastroenterology studies
- Diagnosis and treatment of tuberculosis
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Hepatitis C virus research
- Viral Infections and Outbreaks Research
- Immunodeficiency and Autoimmune Disorders
- Pediatric health and respiratory diseases
- Parasites and Host Interactions
- Mycobacterium research and diagnosis
Svenska Örtmedicinska Institute
2024
Karolinska Institutet
2019-2024
Xijing Hospital
2024
Zhejiang Center for Disease Control and Prevention
2020-2023
Hangzhou Center for Disease Control and Prevention
2013-2023
National Institute for Communicable Disease Control and Prevention
2022
Wuhan University of Science and Technology
2021
Southern University of Science and Technology
2021
Shenzhen Third People’s Hospital
2021
Science for Life Laboratory
2019
Abstract Bacillus Calmette-Guérin (BCG) vaccine has failed to control the global tuberculosis (TB) epidemic, and there is a lack of safe effective mucosal vaccines capable potent protection against pulmonary TB. A recombinant replication-deficient adenoviral-based expressing an immunogenic Mycobacterium Ag Ag85A (AdAg85A) was engineered evaluated for its potential be used as respiratory TB in murine model single intranasal, but not i.m., immunization with AdAg85A provided airway challenge...
Objective: To assess the prevalence of HIV and selected sexually transmitted diseases (STDs) among men who have sex with (MSM) in Chengdu, China, risk factors associated infection. Methods: A cross-sectional study using a snowball sampling method was conducted from March to July 2007. Participants were asked complete questionnaire about sexual history, high-risk behaviors, STD infection knowledge testing, an assessment depression. Blood samples taken for antibody testing HIV, herpes simplex...
Overseas imported dengue fever is an important factor in local outbreaks of this disease the mainland China. To better prevent and control such outbreaks, epidemiological characteristics temporal-spatial distribution overseas cases provincial-level administrative divisions (PLADs) where outbreak China were explored.Using Chinese National Notifiable Infectious Disease Reporting Information System (CNNDS), we identified areas from 2005 to 2019 draw epidemic curve population characteristic each...
Objective: This study aimed to determine the diagnostic utility of clinician speech ratings and patient self-report for detecting early bulbar changes associated with amyotrophic lateral sclerosis (ALS), compared instrumentation-based measures.Methods: Thirty-six individuals ALS 17 healthy control participants were included. Patients' awareness motor involvement was assessed using self-reported scores on Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R). Clinicians'...
Abstract To investigate the prevalence, types, and risk factors of functional gastrointestinal diseases (FGIDs) in Hainan Province, China, order to provide insights for future prevention treatment strategies. A questionnaire survey was conducted from July 2022 May 2023, using stratified sampling sample local residents five cities (20 townships) Province. Out 2057 surveyed, 659 individuals (32.0%) reported experiencing at least one FGID. The most prevalent FGIDs were dyspepsia (FD) (10.7%),...
Abstract During the COVID-19 pandemic it was widely described that certain individuals infected by SARS-CoV-2 experience persistent disease signs and symptoms, Long COVID, which in some cases is very severe with life changing consequences. To maximize our chances of identifying underpinnings this illness, we have focused on 121 most from >1000 patients screened specialized clinics Sweden Belgium. We restricted study to subjects objective measures organ damage or dysfunction, >3 months...
In 1989, the United States embarked upon an ambitious path to eliminate tuberculosis (TB) nationwide. Although incidence rates of TB disease in are declining, these cases represent only a tiny fraction all infections. Understanding national trends infection may be important anticipating future disease.Describe epidemiology Mycobacterium 1971-1972 and 1999-2000.We studied nationally representative cohorts U.S. noninstitutionalized civilian population participating 1999-2000 National Health...
This study evaluated the effectiveness of a community-based peer intervention to reduce HIV risk among men who have sex with (MSM) in Sichuan province, China. The was based on Popular Opinion Leader framework, which respected MSM leaders attempted change community norms related sexual behavior and risk. conducted metropolitan city, matched city same province serving as comparison. We baseline survey behaviors 200 per provided for 12 months treatment post-treatment an independent sample city....
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<h3>Background:</h3> All Canadian immigrants undergo screening for tuberculosis (TB) before immigration, and selected must postimmigration surveillance the disease. We sought to quantify domestic health impact of TB in all new identify mechanisms enhance effectiveness efficiency this screening. <h3>Methods:</h3> linked preimmigration medical examination records from 944 375 who settled Ontario between 2002 2011 active reporting data 2011. Using a retrospective cohort study design, we...
Abstract We developed a local drug‐release system consisting of two biodegradable polymers, poly(sebacic anhydride) (PSA) and poly‐ D , L ‐lactide (PLA), for the treatment chronic osteomyelitis. PSA PLA were dissolved blended at different ratios in tetrahydrofuran. Ofloxacin was loaded with an 8:1 weight ratio blend to drug. The ofloxacin‐containing beads PSA/PLA made by preheating compressing them mold. vitro drug release showed that changing between polymers caused effective...
Background: 23-valent pneumococcal polysaccharide vaccine (PPSV23) has been used to prevent disease, and PPSV23 became available in 2003 Hangzhou, China as a private-sector, vaccinee-chosen vaccine. No national guidelines for have developed. We analyzed coverage utilization Hangzhou determine patterns of use the occurrence adverse events following immunization (AEFI) Hangzhou.Materials Methods: Individuals over 2 years age were included. Vaccination data during 2006–2017 was retrieved from...
The present study aimed to estimate the prevalence of syphilis among men who have sex with (MSM) currently married women in cities China and examine related factors for them."Snowballing" sampling was used recruit participants 4 from April 2008 August 2009. Information collected anonymously remained confidential. Blood samples were all eligible HIV tests.A total 858 participated study, their average age 38.3 years (ranged 21 75 years). Fifty-three percent did not residence cards, 37%...
Objective To delineate seroepidemiology of VZV in children aged 1-14 years Hangzhou, to evaluate immunological response VarV via 2 dose regimen immunization VarV, for improving strategy VarV. Methods From 2014-2016, a multi-stage stratified random sampling method was employed select participants included physical examination the Community Health Centre Hangzhou. Results were compared among 11 various age groups: 1-,2-,3-,4-,5-,6-,7-,8-,9-,10-,11-14 years. Demographic data and vaccination...
Objective To explore the prevalence of type I and II Helicobacter pylori infection investigate risk factors in a population from Hainan Province China. Methods Data came large, cross-sectional study conducted August 2022 to April 2023 involving five cities Hainan. Subjects with confirmed 14C-urea breath test (UBT) positive serological assay were included. All subjects had gastroscopy. According presence or absence CagA/VacA proteins, classified as either (present) strains (absent)....
Following the national proclaim of Measles Elimination 2012, plenty activities for controlling incidence had practiced in Hangzhou. However, did not decrease to low degree and remained perform as gap elimination target. The present study aimed describe epidemiological characteristics measles, proposed reasonable method target Hangzhou.Cases were collected by National Notifiable Diseases Surveillance System (NNDSS) from 2004 2011. descriptive epidemiology was employed analyze measles.A total...
This study aimed to evaluate the implementation and impact of rubella-containing vaccine (RCV) by describing rubella epidemiology seroepidemiology in Hangzhou. We collected cases Hangzhou Information System for Disease Control Prevention China between 2009 2020, performed a descriptive analysis. applied multi-stage stratified random sampling method recruit participants serological tests rubella. Enzyme Linked Immunosorbent Assay (ELISA) was used detect Immunoglobulin G (IgG) antibodies...
The aim of this study was to evaluate the seroprevalence rubella antibodies and factors associated with antibody seropositivity after vaccination among healthy children aged 14 below. A multi-stage stratified random sampling method employed recruit participants for serological test. An enzyme-linked immunosorbent assay used detect human IgG avidity virus in sera participants. Univariate multivariate analyses were analyze associations between variables. total 778 subjects included subsequent...
Objective: To delineate seroepidemiology of pertussis in Hangzhou, to evaluate the protection levels among healthy populations, for improving prevention strategy pertussis.Methods: During 2009-2017, a multistage stratified random sampling method was employed select participants included via physical examination subjects several Community Health Centers Hangzhou. Enzyme-Linked Immunosorbent Assay (ELISA) used detect Immunoglobulin G (IgG) antibodies against serum samples. Results were...
OBJECTIVE: To determine the feasibility and effectiveness of HIV risk behavior intervention characterized by initiator taking lead combined with peers participation as to preventing epidemic through promoting condom use reducing number sexual partners among men who have sex (MSM) groups. METHODS: Subjects were recruited via peer referral chain. Twelve key MSM initiators in bars or other venues 3 cities Hefei Wuhu Fuyang. Then each up participate also them continued recruiting others. A total...
Objective To describe the epidemiological characteristics of contraindications in children routine vaccination, to evaluate vaccination doctors' ability determine contraindications. Method Using cross-section study, 34 urban and 15 suburb units were selected from 206 Community Health Center (CHC) Hangzhou, China. Subjects all coming CHCs for vaccination. All situations considered be unsuitable recorded as 3 experts used classify these abnormal records true or false Then, multi-analysis was...