A5043718865- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Gut microbiota and health
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Dietary Effects on Health
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Tryptophan and brain disorders
- Pathogenesis and Treatment of Hiccups
- Mycobacterium research and diagnosis
- Galectins and Cancer Biology
- Intensive Care Unit Cognitive Disorders
- Inflammatory mediators and NSAID effects
- Microbial Metabolites in Food Biotechnology
- Genetic factors in colorectal cancer
- Pharmacogenetics and Drug Metabolism
- Veterinary medicine and infectious diseases
- Microscopic Colitis
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Complementary and Alternative Medicine Studies
Hainan Medical University
2023-2025
Hainan Medical College Hospital
2022
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2022
Acute gastrointestinal infections can lead to post-infectious irritable bowel syndrome (PI-IBS). Moreover, coronavirus disease (COVID-19) is related long-term sequelae. In this study, the frequency, spectrum, and risk factors for post-infection functional (PI-FGID) in COVID-19 patients healthy controls were prospectively examined.
Coronavirus disease 2019 (COVID-19) can lead to persistent symptoms, sequelae, and other medical complications that may last for weeks or months after recovery. The aim of the study is assess prevalence risk factors long COVID-19 persisting 2 years in Hainan Province, China, aid its recognition, prevention, treatment. Between July August 2022, 960 individuals with confirmed SARS-CoV-2 infection Hainan, were recruited. An epidemiological questionnaire was conducted via phone interviews...
Objective Metabolic Associated Fatty Liver Disease (MAFLD) impacts approximately 25% of the global population. The objective our study was to elucidate characteristics gut microbiome and alterations in plasma metabolites among MAFLD patients.
Antibiotic resistance is the most important factor leading to failed Helicobacter pylori eradication therapy, and personalized treatment based on antibiotic susceptibility becoming increasingly important. To strengthen understanding of genotypic H. identify new loci, in this study, we identified phenotypic information for 60 clinical isolates compared concordance using whole-genome sequencing (WGS). Clarithromycin levofloxacin was almost perfect with resistance, kappa coefficients 0.867...
Abstract To investigate the prevalence, types, and risk factors of functional gastrointestinal diseases (FGIDs) in Hainan Province, China, order to provide insights for future prevention treatment strategies. A questionnaire survey was conducted from July 2022 May 2023, using stratified sampling sample local residents five cities (20 townships) Province. Out 2057 surveyed, 659 individuals (32.0%) reported experiencing at least one FGID. The most prevalent FGIDs were dyspepsia (FD) (10.7%),...
Purpose: Recurrence rate of Helicobacter pylori ( H. ) infection after successful eradication have gained attention. This study was to assess the recurrence in southern coastal provinces China and analyze its factors. Patients Methods: 975 patients with upper gastrointestinal symptoms who were diagnosed using 13C or 14C-urea breath test (UBT) underwent treatment between August 2021 December 2022. After eight twelve weeks, repeat UBT performed. Besides, 824 a by completing questionnaires...
Abstract H. pylori infection is gaining increasing attention, but detailed investigations into its impact on gastric microbiota remain limited. We collected mucosa samples from 47 individuals divided three groups: 1. Group HP: patients with initial positive (25 cases); 2. ck: -negative (14 3. DiffHP: refractory (8 cases). The were analyzed using 16S rDNA sequencing and functional prediction PICRUSt. HP showed differences in flora distribution function compared to ck, while DiffHP overlapped...
Abstract Objective The aim of this study was to understand the prevalence and potential risk factors Helicobacter pylori ( H. ) infection in Hainan Province, China. Methods We conducted 21 health service stations 5 cities Province from August 2022 April 2023. selected various participants based on a stratified whole-group sampling method. 14C-UBT used analyze 3632 participants. also analyzed possible relationship between variables chi-square test multifactorial logistic regression. model...
Abstract Objective To compare the potential efficacy and safety of dual therapy quadruple with vonoprazan (VPZ) as well standard proton pump inhibitor (PPI) for eradication Helicobacter pylori (Hp) infection in Hainan province. Methods A single-centre, non-blinded, non-inferiority randomized controlled trial was conducted at outpatient department gastroenterology Second Affiliated Hospital Medical University from June 2022 to February 2023. 135 patients aged 18–75 years Hp were enrolled into...
Objective: The present study aims to compare the safety and efficacy of an amoxicillin/ilaprazole regimen with a bismuth quadruple as first-line treatment for eradicating Helicobacter pylori (H. pylori) infection. Methods: This was open-label, randomized, single-center involving 450 patients untreated H. infection who were randomly assigned Ilaprazole-amoxicillin-furazolidone-bismuth glycyrrhizinate (IAFB) therapy group 14 days, 10 or Ilaprazole-amoxicillin (IA) dual days. 13C urea breath...
Abstract Purpose There is controversy concerning the relationship between Helicobacter pylori ( H. ) infection and osteoporosis. This study to examine causal osteoporosis analyze potential mechanism underlying relationship. Methods The clinical data of bone mineral density from patients or physical examiner with good general condition in our hospital September 2019 2020 were retrospectively collected. was compared analyzed, using logistic regression association. To investigate effects...
Abstract Background: Acute gastrointestinal infections can lead to post-infectious irritable bowel syndrome (PI-IBS). Moreover, coronavirus disease (COVID-19) is related long-term sequelae. In this study, the frequency, spectrum, and risk factors for post-infection functional (PI-FGID) in COVID-19 patients healthy controls were prospectively examined. Methods: Validated Rome III IV questionnaires used assess incidence of PI-FGID 190 patients, 160 followed 1, 3, 6 months. Results: Six（3.2%）,...