A5100384549- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Sarcoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Head and Neck Surgical Oncology
- Spinal Fractures and Fixation Techniques
- Spinal Dysraphism and Malformations
- Oral and Maxillofacial Pathology
- Cancer-related molecular mechanisms research
- Soft tissue tumor case studies
- Cardiac Valve Diseases and Treatments
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cerebrospinal fluid and hydrocephalus
- Ocular Oncology and Treatments
- Facial Nerve Paralysis Treatment and Research
- Management of metastatic bone disease
- Neurosurgical Procedures and Complications
- Teratomas and Epidermoid Cysts
Shanghai Jiao Tong University
2024-2025
Beijing Tian Tan Hospital
2015-2024
Capital Medical University
2015-2024
Ningbo No. 2 Hospital
2024
General Hospital of Shenyang Military Region
2023-2024
Capital University
2014-2024
University of Nottingham Ningbo China
2024
Shanghai University of Traditional Chinese Medicine
2023
National Clinical Research Center for Digestive Diseases
2015-2023
Sichuan University
2019-2023
The aim of this study was to evaluate the pre- and postoperative rehemorrhage risk, neurological function outcome, prognostic factors surgically treated brainstem cavernous malformations (CMs) with long-term follow-up.The authors conducted a retrospective review clinical data from 242 patients CMs that were between 1999 2010. Patient charts, imaging findings, outcomes examined.The included patients, male-to-female ratio 1.3 mean age 32.6 years. modified Rankin Scale scores on admission, at...
OBJECT.: Cerebral cavernous malformations have been studied widely, but the natural history of brainstem (CMs) is not well defined, and hemorrhages caused by CMs are devastating. The goal this study was to quantify hemorrhage risks functional outcomes patients with CMs.This prospective, longitudinal, cohort included diagnosed between 1985 2012. clinical courses all were recorded. Predictors overall untreated evaluated.A total 331 (46.5% female) included, a mean follow-up duration 6.5 years....
OBJECTIVE Skull base chordoma is relatively rare, and a limited number of reports have been published regarding its clinical features. Moreover, the factors associated with extent resection, as well value marginal resection for long-term survival, are still in question this disease. The objective study was to investigate these by evaluating their features surgical outcomes. METHODS A retrospective analysis 238 patients skull chordomas, who met inclusion criteria, performed. This summarized...
The goal of this study was to evaluate surgical outcomes pediatric brainstem cavernous malformations (CMs) and identify the risk factors associated with postoperative full recovery rebleeding.The clinical charts radiographs from a series 52 patients (37 male 15 female; mean age 12.2 years; range 1-17 years) who underwent surgery for CMs between 1996 2011 were reviewed. Follow-up evaluation measures obtained retrospectively. Neurological function evaluated using modified Rankin Scale (mRS)...
The aim of this study was to investigate the clinical appearance untreated pediatric brainstem cavernous malformations (CMs) and identify hemorrhage risks functional outcomes.All patients with a diagnosis CM between 1985 2012 were registered. chart radiographs recorded, follow-up evaluations obtained prospectively.A total 85 (69.4% male) included mean age 12.7 years. Sixty-seven (78.8%) had prior hemorrhage, 6 (7.1%) asymptomatic. There 15 midbrain lesions, 53 pons 17 medulla lesions. lesion...
OBJECTIVE Surgical management of brainstem lesions is challenging due to the highly compact, eloquent anatomy brainstem. This study aimed evaluate safety and efficacy preoperative diffusion tensor imaging (DTI) tractography (DTT) in cavernous malformations (CMs). METHODS A prospective randomized controlled clinical trial was performed by using stratified blocked randomization. The primary eligibility criterion being a surgical candidate for CMs (with informed consent). enrolled 23 patients...
Given the paucity of data on natural history brainstem cavernous malformations (CMs), authors aimed to evaluate annual hemorrhage rate and hemorrhagic risk CMs.
Abstract Background Colorectal cancer (CRC) is a malignant tumor of the digestive system that contains high levels immune cells. Lactic acid, major metabolite, plays crucial role in development, maintenance, and therapeutic response. However, prognostic potential biomarker lactate‐related genes (LRGs) CRC patients remain to be elucidated. Methods We collected mRNA expression profile clinical data from Cancer Genome Atlas (TCGA) database GSE59382 cohort. Univariate Cox regression, Lasso...
OBJECTIVE The natural history of cerebral cavernous malformations (CMs) has been widely studied, but the clinical course untreated thalamic CMs is largely unknown. Hemorrhage these lesions can be devastating. authors undertook this study to obtain a prospective hemorrhage rate and provide better understanding prognosis CMs. METHODS This longitudinal cohort included patients with who were diagnosed between 2000 2015. Clinical data recorded, radiological studies extensively reviewed, follow-up...
BACKGROUND. Lower-grade gliomas (LGGs) vary widely in terms of the patient's overall survival (OS). There is no current, valid method that could exactly predict survival. The effects intratumoral immune infiltration on clinical outcome have been reported. Thus, we aim to develop an signature LGG patients.
OBJECTIVE This study aimed to evaluate neurological function and progression/recurrence (P/R) outcome of foramen magnum meningioma (FMM) based on a modified classification. METHODS included 185 consecutive patients harboring FMMs (mean age 49.4 years; 124 females). The authors classified the into 4 types according previous classification Bruneau George as follows: Type A (n = 49, 26.5%), dural attachment lesion grows below vertebral artery (VA); B 39, 21.1%), above VA; C1 84, 45.4%), VA...
Abstract The guideline for the treatment of interrupted aortic arch (IAA) in adults has not been established although most centers tend to propose surgery. There is no clear evidence preferred selection surgical repair versus conservatively medical uncertain effects both treatments. However, reports sporadic dissection (AD) descending aorta (DAo) IAA before surgery drew our attention. It quite perplexing because there seems be risk factors development AD at DAo such as long-term uncontrolled...
OBJECTIVE The aim of this study was to analyze the neurological functional outcome and recurrent risks in surgically treated jugular foramen paragangliomas (JFPs) propose an individualized therapeutic strategy. METHODS Clinical charts radiological information were reviewed retrospectively 51 consecutive cases JFPs. Less-aggressive surgical interventions adopted with goal preserving neurovascular structures. Scheduled follow-up performed. RESULTS mean age patients 41.6 years, group included...