A5084307791- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Cancer-related molecular mechanisms research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Actinomycetales infections and treatment
- Nosocomial Infections in ICU
- Infectious Diseases and Mycology
- HIV-related health complications and treatments
- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- Infection Control in Healthcare
- Viral Infections and Outbreaks Research
- COVID-19 and Mental Health
- Global Maternal and Child Health
- HIV/AIDS Research and Interventions
- Streptococcal Infections and Treatments
University of Zimbabwe
2015-2021
Bindura University of Science Education
2021
Extended-spectrum β-lactamase-producing and gentamicin resistant Enterobacteriaceae are increasingly recognised as a major cause of infection in low-income countries. We assessed the prevalence gastrointestinal carriage these bacteria hospitalised children Harare, Zimbabwe.We conducted cohort study paediatric inpatients at two tertiary-referral hospitals between May July 2015. Rectal swabs faecal samples were collected within 24 h admission further follow-up on alternate days during...
Mycobacterium species are naturally found in the environment as well domestic animals such cattle. So far, more than 150 of , some which pathogenic, have been identified. Laboratory isolation, detection and identification therefore critical if human animal infections to be controlled. The objective this study was identify isolated cattle Zimbabwe using 16S ribosomal RNA gene amplification sequencing. A total 134 cow dung samples were collected throughout mycobacteria by culture. Only 49...
Bloodstream infections (BSI) caused by Enterobacteriaceae show increasing frequency of resistance to third-generation cephalosporin (3GC) antibiotics on the African continent but mortality impact has not been quantified.We used historic data from six hospitals assess 3GC clinical outcomes in Escherichia coli and Klebsiella pneumoniae BSI. We matched each bacteraemic patient two uninfected patients. compared between 3GC-susceptible 3GC-resistant BSI their respective controls using Cox...
ObjectiveTo define sepsis syndromes in high-HIV burden settings the antiretroviral therapy (ART) era.MethodsWe characterized a prospective cohort of adults presenting to tertiary emergency department Harare, Zimbabwe with suspected community-acquired using blood and urine cultures, tuberculosis lipoarabinomannan (TB LAM), serum cryptococcal antigen (CrAg) testing. The primary outcome was 30-day all-cause mortality.ResultsOf 142 patients enrolled 68% (n = 96/142, 95% confidence interval (CI)...
We assessed bacterial contamination of hands adults present in paediatric wards two tertiary-care hospitals Harare, Zimbabwe and the microbiologic efficacy locally-manufactured alcohol-based hand rub (ABHR). During unannounced visits, samples were collected using hand-print hand-rinse methods. Samples from 152 individuals (16 nurses, 10 doctors, 28 students, 86 parents/guardians, 12 others). Contamination with Gram-negative bacteria was found 91% tested a mean 14.6 CFU (hand-rinse method;...