A5090779352- Ovarian function and disorders
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Endometriosis Research and Treatment
- Reproductive Health and Technologies
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Cardiovascular Issues in Pregnancy
- Reproductive System and Pregnancy
- Hormonal Regulation and Hypertension
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Genetics and Neurodevelopmental Disorders
- LGBTQ Health, Identity, and Policy
- Ectopic Pregnancy Diagnosis and Management
- Sexual Differentiation and Disorders
- Organ and Tissue Transplantation Research
- Neuropeptides and Animal Physiology
- Pregnancy-related medical research
- Neonatal and fetal brain pathology
- Maternal and fetal healthcare
- Sperm and Testicular Function
- Reproductive Physiology in Livestock
- Congenital Heart Disease Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2003-2024
Hospital Clínic de Barcelona
2015-2024
Fundació Clínic per a la Recerca Biomèdica
2024
Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer
2024
Universitat de Barcelona
2008-2023
Centre for Biomedical Network Research on Rare Diseases
2017
Center for Digestive and Liver Diseases
1998
BACKGROUND: Anti-Müllerian hormone (AMH) has been recently proposed as a marker for ovarian ageing and poor response to controlled hyperstimulation in assisted reproduction cycles. The present study was undertaken investigate the usefulness of baseline cycle day 3 AMH levels serum concentrations obtained on fifth gonadotropin therapy predicting pregnancy women undergoing stimulation with FSH under pituitary desensitization reproduction. METHODS: A total 80 their first IVF/intracytoplasmic...
Studies in macaques have indicated that androgens some synergistic effects with FSH on folliculogenesis. This study investigated the usefulness of pretreatment transdermal testosterone low-responder IVF patients.Randomized clinical trial including 62 infertile women who had a background first treatment cycle cancelled because poor follicular response. Patients were randomized two groups their second attempt. In patients Group 1 (n = 31), application preceding standard gonadotrophin ovarian...
Treatment of poor-responder patients to controlled ovarian stimulation for assisted reproduction, who have normal basal FSH concentrations, is one the most difficult challenges in reproductive medicine. This study investigated usefulness testosterone pretreatment such patients.Prospective, therapeutic, self-controlled clinical trial including 25 consecutive infertile had a background first and second IVF treatment cycle cancellations due poor follicular response, spite vigorous gonadotrophin...
The present study is the first prospective randomized controlled trial of effect pentoxifylline on future fertility in infertile women with asymptomatic minimal or mild endometriosis. After completion a basic infertility workup and laparoscopy, patients were entered into randomly allocated to receive either 12 month course oral (800 mg/day) (n = 30) an placebo 30). Those other factors included only if correctable ultimately determined be non-contributory. Life-table analysis was used compare...
BACKGROUNDSurgical treatment has modest efficacy for the of infertility associated with early-stage endometriosis. Immunomodulation pentoxifylline is considered as a new strategy potentially useful in treating Thus, this study investigated usefulness combined laparoscopic surgery and therapy minimal to mild
Marked granulosa cell proliferation along with important changes in the vascular bed of ovary characterize IVF cycles associated multiple follicular growth and maturation. The present report investigated fluid (FF) circulating concentrations adrenomedullin, endothelial factor (VEGF) nitric oxide (NO) 70 patients (14 whom became pregnant); these three vasoactive substances may be implicated extensive ovarian tissue remodelling. Serum FF oestradiol progesterone were also measured studied....
There has been much debate about the effect of 'residual' LH levels in normogonadotrophic women undergoing assisted reproduction with GnRH agonist down-regulation and recombinant FSH ovarian stimulation. The aim this prospective study, where receiver-operating characteristic (ROC) analysis was used, to assess further usefulness serum as predictors response, treatment outcome, outcome pregnancy when measured throughout stimulation period a large cohort such women.A total 246 consecutive their...
We aimed to explore fetal cortical brain development by neurosonography in fetuses conceived assisted reproductive technology (ART), including frozen and fresh embryo transfer (ET), compared with those spontaneously (SC), investigate its association infant neurobehavior at 12 months of age.
Do fetuses from frozen embryo transfer (FET) present signs of cardiac remodeling and suboptimal function similar to those observed in fresh (ET)?Fetuses both ET FET fetal function, with more pronounced changes after as compared FET.Our group others have previously demonstrated that children conceived by ARTs function. These show dilated atria, globular thicker ventricles, reduced longitudinal motion, impaired relaxation. Cardiac were already utero persisted birth. Most the ART included...
Severe ovarian hyperstimulation syndrome is an uncommon cause of ascites that being increasingly recognized because the high number women undergoing assisted reproductive techniques, mainly in vitro fertilization. This prospective study investigates clinical and biochemical characteristics a large series patients with this ascites, including renal electrolyte abnormalities, activity neurohormonal systems participating regulation extracellular fluid volume, liver function tests.This was...
Objectives To examine perinatal outcomes in pregnancies conceived by different methods: fertile women with spontaneous pregnancies, infertile who achieved pregnancy without treatment, ovulation induction (OI) and vitro fertilization or intra-cytoplasmic sperm injection (IVF/ICSI).
Objective: To analyze global outcomes in frozen-thawed embryo transfer according to endometrial preparation with natural cycle and artificial taking into account the developmental stage of embryo.Methods: Retrospective cohort study, held a tertiary-care university hospital 1265 cycles for 860 patients, performed between January 2014 December 2017. A total 1097 transfers were performed: 163 (N), 531 cycle: transdermal estrogens 403 oral estrogens.Results: Demographical factors similar three...
Previous studies have shown that severe ovarian hyperstimulation syndrome (OHSS) is secondary to circulatory dysfunction due the simultaneous occurrence of increased vascular permeability and marked arteriolar vasodilation which lead an intense homeostatic stimulation renin-aldosterone sympathetic nervous systems antidiuretic hormone (ADH). In present report, we investigated correlation between changes in haematocrit concentration, white blood cell (WBC) platelet counts severity OHSS, as...
Severe ovarian hyperstimulation syndrome (OHSS) is consistently associated with a circulatory dysfunction characterized by arterial hypotension, low peripheral vascular resistance, and increased activity of the renin-aldosterone system. To investigate whether also occurs in asymptomatic patients undergoing controlled gonadotropin under pituitary suppression for vitro fertilization (IVF), 12 women without clinical manifestations OHSS underwent sequential blood, urine, hemodynamic measurements...