A5068764752- Leech Biology and Applications
- Species Distribution and Climate Change
- Healthcare and Venom Research
- Venomous Animal Envenomation and Studies
- Circular RNAs in diseases
- Identification and Quantification in Food
- RNA modifications and cancer
- RNA Research and Splicing
Guangxi University
2022-2023
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2022-2023
Abstract Cattle and the draught force provided by its skeletal muscle have been integral to agro‐ecosystems of agricultural civilization for millennia. However, relatively little is known about cattle functional genomics (including protein coding genes, non‐coding RNA, etc.). Circular RNAs (circRNAs), as a new class RNAs, can be effectively translated into detectable peptides, which enlightened us on importance circRNAs in physiology function. Here, RNA‐seq, Ribosome profiling (Ribo‐seq),...
Abstract Background Leeches have been used in traditional Chinese medicine since prehistoric times to treat a spectrum of ailments, but very little is known about their physiological, genetic, and evolutionary characteristics. Findings We sequenced assembled chromosome-level genomes 3 leech species (bloodsucking Hirudo nipponia Hirudinaria manillensis nonbloodsucking Whitmania pigra). The dynamic population histories genome-wide expression patterns the 2 bloodsucking were found be similar. A...
Hirudo nipponia is the only blood-sucking leech included in Chinese Pharmacopoeia having distinct features of anticoagulation, exorcizing blood stasis, and promoting menstruation. Despite such significant characteristics, very little known about its molecular genetics related physiological mechanisms. In this study, transcriptomes H. at three developmental stages (larvae, young, adults), revealed a total 1,348 differentially expressed genes (DEGs), 223 lncRNAs, 88 novel mRNAs. A diverse gene...
Medical leeches are widely been used in biochemical and clinical medical studies, helping to restore blood circulation grafted or severely injured tissue. Mostly, adult being the traditional pharmacopeia, but gene expression profiling of different growth periods is not well-reported. So, this study, we transcriptome analysis analyze comparative patterns Hirudinaria manillensis (H. manillensis) periods, including larval, young, stages. We constructed 24 cDNA libraries from H. stages, about...