A5102894265- Pharmacogenetics and Drug Metabolism
- Antifungal resistance and susceptibility
- Neural and Behavioral Psychology Studies
- Drug Transport and Resistance Mechanisms
- Chronic Myeloid Leukemia Treatments
- Epigenetics and DNA Methylation
- Chronic Lymphocytic Leukemia Research
- Influenza Virus Research Studies
- Acute Lymphoblastic Leukemia research
- Visual perception and processing mechanisms
- Nail Diseases and Treatments
- Neural dynamics and brain function
- HIV Research and Treatment
- SARS-CoV-2 and COVID-19 Research
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Fungal Infections and Studies
- vaccines and immunoinformatics approaches
- Infection Control and Ventilation
- Seismology and Earthquake Studies
- Ophthalmology and Eye Disorders
- Cardiovascular Disease and Adiposity
- Dental Research and COVID-19
- Pain Management and Opioid Use
- Bacterial biofilms and quorum sensing
Yunnan Earthquake Prevention and Disaster Reduction
2025
Central South University
2024
Second Xiangya Hospital of Central South University
2024
Peking University People's Hospital
2021-2023
Peking University
2021-2023
Guangzhou Center for Disease Control and Prevention
2021
University of Waterloo
2021
University of California, San Francisco
2015
Northrop Grumman (United States)
2013
University of Minnesota
2006-2010
Cognitive impairments have been found in thyroid hormone-related diseases (e.g. hyperthyroidism and hypothyroidism) for a long time. However, whether how subclinical hypothyroidism (SCH) causes any deficits brain functions, hormone-replacement treatment is necessary SCH patients, still remain controversial subjects. In the present study, functional MRI (fMRI) was used to measure functions by asking euthyroid subjects, hyperthyroid patients perform widely digit n-back working memory task....
Fault displacement hazard, along with ground shaking hazard and earthquake-induced geohazard, are the primary forms of disaster in major earthquakes. Buildings located on areas strong seismic surface likely to be damaged if anti-displacement design is not carried out. Therefore, a reasonable targeted active fault classification scheme helpful for avoidance engineering construction. However, existing schemes rough, some have no quantitative basis, which makes it difficult apply these actual...
Crowding effect is the visibility reduction of a target when presented with neighboring distractors. It has been explained by either lateral inhibition at pre-attentive level or coarse spatial resolution attention. To test these theories, high-resolution fMRI was used to measure V1 response in presence absence distractors both attended and unattended conditions. We found cortical not affected condition. However, distribution attention modulation its surrounding area depended on crowding...
ObjectiveTo determine the duration of SARS-CoV-2 persistence in quarantine hotel environments.Methods39 Patients confirmed by RT-PCR were included. We collected clinical features, laboratory test results, smear sample information, and room information. Genome sequencing phylogenetic analysis conducted. analyzed factors associated with environmental contamination.ResultAmong 39 COVID-19 cases, 10 asymptomatic 37 imported from aboard. 271 swab samples surfaces related to observational...
Epicardial adipose tissue (EAT) significantly contributes to the progression of cardiovascular diseases (CVDs). However, manually quantifying EAT volume is labor-intensive and susceptible human error. Although there have been some deep learning-based methods for automatic quantification EAT, they are mostly uninterpretable fail harness complete anatomical characteristics. In this study, we proposed an enhanced learning method designed on coronary computed tomography angiography (CCTA) scan,...
Abstract Background Fungal infections remain a substantial cause of mortality in lung transplant ( LT x) recipients, yet no comprehensive consensus guidelines have been established for antifungal prophylaxis and treatment Aspergillus infection these patients. Methods A cross‐sectional study surveyed the directors from 27 64 (45.5%) active x centers United States to examine clinical practice variations colonization invasive aspergillosis IA ) recipients. Results Antifungal increased 52.3%...
It is long believed that the human visual system comprises two main pathways, a ventral pathway explicitly represents perceptual experience and dorsal can process information guide action without accompanying conscious knowledge. Evidence for this theory has primarily come from studies of neurological patients animals. Here, we used functional Magnetic Resonance Imaging (fMRI) to measure cortical responses invisible objects in object-selective areas. When low-contrast stationary images are...
Interindividual differences in drug response have always existed clinical treatment. Genes involved absorption, distribution, metabolism, and excretion (ADME) play an important role the process of pharmacokinetics. The effects genetic polymorphism nuclear receptors on expression metabolism enzymes transporters can only explain some individual Several key ADME genes been demonstrated to be regulated by epigenetic mechanisms that potentially affect inter-individual variability medical Emerging...
As the major target of many vaccines and neutralizing antibodies against SARS-CoV-2, spike (S) protein is observed to mutate over time. In this paper, we present statistical approaches tackle some challenges associated with analysis S-protein data. We build a Bayesian hierarchical model study temporal spatial evolution sequences, after grouping sequences into representative clusters. then apply sampling methods investigate possible changes S-protein's 3-D structure as result commonly...
How does prolonged reduction in retinal-image contrast affect visual-contrast coding? Rubin and Legge (Vision Research, 29, 79–91, 1989) proposed that vision through cataracts some other ocular-media opacities can be modeled by a contrast-reducing “filter” front of an otherwise normal visual system (contrast attenuation model). Recent evidence, however, indicates forms long-term deprivation result compensatory perceptual neural changes the adult pathway. The goal our study is to investigate...
Background: Fungal infections remain a substantial cause of mortality in lung transplant (LTx) recipients, yet there are no consensus guidelines established for antifungal prophylaxis and treatment Aspergillus infection these patients. Methods: A cross-sectional study surveyed the directors from 27 64 (45.5%) active U.S. LTx centers to examine clinical practice variations colonization invasive aspergillosis (IA) recipients. Results: 77.8% reported using prophylaxis, with most common agent...
It was recently reported that a subliminalflicker could trigger attentional selection at the target location (Bauer et al, PNAS 2009). They specifically attributed this effect to middle of gamma range (50Hz) since they failed find such with flickers slower than 35-Hz. However, it is possible rendering flicker signal subliminal by lowering its contrast resulted in more severe loss effective neural for 30 Hz 50 flicker. To test possibility, we used reduction combined spatial crowding render...
As the major target of many vaccines and neutralizing antibodies against SARS-CoV-2, spike (S) protein is observed to mutate over time. In this paper, we present statistical approaches tackle some challenges associated with analysis S-protein data. We build a Bayesian hierarchical model study temporal spatial evolution sequences, after grouping sequences into representative clusters. then apply sampling methods investigate possible changes S-protein's 3-D structure as result commonly...