A5042320928- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Oral and Maxillofacial Pathology
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Soft tissue tumor case studies
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Total Knee Arthroplasty Outcomes
- COVID-19 and healthcare impacts
- Soft tissue tumors and treatment
- Reconstructive Surgery and Microvascular Techniques
- Urologic and reproductive health conditions
- Musculoskeletal synovial abnormalities and treatments
- Cancer Treatment and Pharmacology
- Musculoskeletal Disorders and Rehabilitation
- Shoulder and Clavicle Injuries
- Medical Imaging and Pathology Studies
- Orthopedic Infections and Treatments
- HER2/EGFR in Cancer Research
- Gastrointestinal Tumor Research and Treatment
- Histiocytic Disorders and Treatments
- Historical Studies in Science
Hospital Universitario La Paz
2014-2025
MD Anderson Cancer Center Madrid
2012-2022
Clinical Orthopaedics and Related Research
2019
Massachusetts General Hospital
1995-2005
Harvard University
1995-2005
Mount Sinai Hospital
1997
We reviewed the results of 104 intercalary allograft procedures that had been performed, between April 1974 and August 1992, in 100 patients, usually after resection a segment bone because an osseous neoplasm. The median duration follow-up was 5.6 years. Retention graft return to essentially normal function were measures success and, on basis, eighty-seven (84 per cent) reconstructions successful. Of fifteen limbs which reconstruction failed, four salvaged with insertion second three, use...
A biopsy is the final step in diagnosis of sarcomas. Complete resection tract traditionally has been recommended musculoskeletal oncology guidelines, as that considered potentially seeded with tumor cells. However, to our knowledge, frequency and implications contamination tract-specifically respect likelihood local recurrence-and factors affect cell seeding are not well described.We asked: (1) How often tracts contaminated pathologically detectable cells at time resection? (2) What factors,...
Objectives . To determine the validity of clinical and radiological features enchondroma low grade chondrosarcoma, contrast biopsy results with diagnosis based on history imaging. Material Method The study included 96 patients cartilage type lesions suggestive an (E) or chondrosarcoma (LGC) according to imaging data. hypotheses were contrasted biopsy. Results Of 82 studied completely, 56 considered E (68.29%), 8 as LGC (8.33%) in 18 (18.75%) doubtful cases suspected LGC. these, showed 4...
Reconstruction after internal hemipelvectomy resection likely provides better function than hindquarter amputation. However, many reconstruction methods have been used, complications with these approaches are common, and often is poor; because of issues, it seems important to investigate alternative implants surgical techniques.The purposes this study were (1) identify the frequency site infection associated use Ice-Cream Cone prosthesis for oncological indications; (2) evaluate...
Abstract Background Desmoid tumours (DTs) or deep fibromatosis are benign soft-tissue tumours, sometimes locally aggressive, requiring intervention on some cases. Surgery has been the gold standard, but new less invasive techniques such as percutaneous cryoablation have proved their effectiveness, reducing health resources and complications. The study aimed to compare total cost of conventional surgery for patients with extra-abdominal and/or abdominal wall DTs, candidates local ablative...
Introduction: Liposclerosing myxofibrous tumors (LSMFTs) have been described as an infrequent and peculiar fibrous dysplasia variant with a predilection for the intertrochanteric femoral region are not globally considered distinct tumor. Given their features, they may be confused variety of entities. Our aim is to analyze clinical, radiological, histopathological molecular features LSMFTs. Material Methods: We report 15 new LSMFT cases managed in our tertiary referral hospital compare...
As of today two types cartilage tumors remain a challenge even for the orthopedic oncologist: enchondroma (E), benign tumor, and chondrosarcoma (LGC), malignant low aggressiveness tumor. A prospective study 133 patients with cartilaginous tumor in long bones appendicular skeleton was done to prove this difficult differential diagnosis. Parameters including medical history radiological nuclear imaging were collected compared result biopsy. scale applied each patient according number episodes...
Primary malignant bone tumors are uncommon and heterogeneous malignancies. This document is a guideline developed by the Spanish Group for Research on Sarcoma with participation of different specialists involved in diagnosis treatment sarcomas. The aim to provide practical recommendations intention helping clinical decision-making process. requires multidisciplinary approach, involving as minimum pathologists, radiologists, surgeons, radiation medical oncologists. Early referral specialist...
Survival in patients who have Ewing sarcoma is correlated with postchemotherapy response (tumor necrosis). This treatment has been categorized as the rate, similar to what used osteosarcoma. There controversy regarding whether this appropriate or it should be a dichotomy of complete versus incomplete response, given how important for overall survival sarcoma. The purpose study was evaluate impact that amount chemotherapy-induced necrosis on (1) survival, (2) local recurrence-free (3)...
Intramedullary nail fixation is commonly used for prophylactic stabilization of impending and complete pathological fractures the long bones. However, metallic artifacts complicate imaging evaluation bone healing or tumor progression postoperative radiation planning. Carbon-fiber implants have gained popularity as an alternative, given their radiolucency superior axial bending. This study evaluates incidences mechanical nonmechanical complications.
Abstract Carbon-fiber (CF) plates are a promising alternative to metal plates. However, reported experience in orthopaedic oncology remains limited. The aim of this study was identify complications patients with bone tumors treated CF Between February 2015 and May 2021, 13 centers retrospectively registered that were reconstructed using Complications identified, timing etiology noted. Similar tabulated classified based on mechanical, non-mechanical paediatric complications. Mechanical...
Eribulin has shown antitumour activity in some soft tissue sarcomas (STSs), but it only been approved for advanced liposarcoma (LPS).In this study, we evaluated the effect of eribulin on proliferation, migration and invasion capabilities LPS, leiomyosarcoma (LMS) fibrosarcoma (FS) models, using both monolayer (2D) three-dimensional (3D) spheroid cell cultures. Additionally, explored combinations with other drugs commonly used treatment STS aim increasing its activity.Eribulin showed...
Abstract Background Tumor surgeons use a variety of endoprosthetic designs for reconstruction after bone tumor resection. However, functional results and implant survival have not been evaluated each design. Because the outcomes failure modes (for example, breakage, loosening) may differ between prosthetic design types, it is important to examine problems associated with different designs. experiences in our practice, we became concerned about surprisingly high frequency device breakage one...
The COVID-19 outbreak has resulted in collision between patients infected with SARS-CoV-2 and those cancer on different fronts. Patients have been impacted by deferral, modification, even cessation of therapy. Adaptive measures to minimize hospital exposure, following the precautionary principle, proposed for care during era. We present here a consensus prioritizing recommendations across continuum sarcoma patient care.A total 125 were soft-tissue, bone, visceral care. Recommendations...
To determine the diagnostic and treatment costs in patients referred to a reference centre with suspected soft tissue sarcoma. The study consisted of historic cohort 48 consecutive who were diagnosed sarcomas (STS) treated our centres between years 2009 2011, both prior after performing biopsy. cost per procedure was taken from official list prices published year 2009. A comparative data performed using Mann–Whitney U Wilcoxon tests. mean patient 14,427.58€. In those before biopsy, overall...