A5068911405- COVID-19 Clinical Research Studies
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Rheumatoid Arthritis Research and Therapies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Urinary and Genital Oncology Studies
- Spondyloarthritis Studies and Treatments
- Chronic Disease Management Strategies
- Urological Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Hip and Femur Fractures
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
- Food Allergy and Anaphylaxis Research
- Inflammatory Biomarkers in Disease Prognosis
- Congenital Heart Disease Studies
- Bone and Joint Diseases
- Bone health and osteoporosis research
- Climate Change and Health Impacts
- Genital Health and Disease
- Drug-Induced Adverse Reactions
- COVID-19 epidemiological studies
Hospital Universitario Fundación Alcorcón
2016-2025
Universidad Rey Juan Carlos
2024
Unidad de Investigación en cuidados y servicios de salud (Investén-isciii)
2021
Hospital Nuestra Señora de Alarcos
2019
Hospital Universitario La Paz
2006-2015
Hospital La Paz Institute for Health Research
2011-2013
Universidad Autónoma de Madrid
2008-2010
It is known that mortality after hip fracture increases compared to the general population; trend in a controversial issue. The objective of this study examine incidence, trends, and factors associated with patients osteoporotic fractures.This retrospective cohort uses Registry for Hospital Discharges National Health System our hospital. Patients older than 45 having an between 1999 2015 were identified. Demographic data comorbidities obtained. A survival analysis was performed (Cox...
Factors associated with the potential for recurrence of keratocystic odontogenic tumours (KCOT) still remain to be clearly determined and no consensus exists concerning management KCOT.The purpose this study was evaluate different clinical factors KCOT its treatment methods.A retrospective review performed 55 cases treated from 2001 2010.Of cases, 27% were an impacted or semiimpacted tooth.The majority lesions (82%) located in tooth-bearing areas, overall mandibular maxilla ratio tumour...
We report on trends in anaphylaxis admissions the Spanish hospital system during period 1998-2011. Data for were obtained from Information System Hospital Patients selected using codes International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM). Poisson regression models used to estimate incidence rate ratios. recorded a 1.89-fold increase hospitals study period, particularly patients aged 0-14 years (1.65- 3.22-fold until 2009 and 4.09- 12.59-fold 2011) food...
Objectives . To determine the validity of clinical and radiological features enchondroma low grade chondrosarcoma, contrast biopsy results with diagnosis based on history imaging. Material Method The study included 96 patients cartilage type lesions suggestive an (E) or chondrosarcoma (LGC) according to imaging data. hypotheses were contrasted biopsy. Results Of 82 studied completely, 56 considered E (68.29%), 8 as LGC (8.33%) in 18 (18.75%) doubtful cases suspected LGC. these, showed 4...
Summary Background Suboptimal response to ursodeoxycholic acid occurs in 40% of primary biliary cholangitis (PBC) patients, affecting survival. Achieving a deep (normalisation alkaline phosphatase [ALP] and bilirubin ≤0.6 upper limit normal) improves Yet, the long‐term effectiveness second‐line treatments remains uncertain. Aims To evaluate obeticholic (OCA) ± fibrates. Focusing on biochemical (ALP ≤1.67 times normal, with decrease at least 15% from baseline normal levels), normalisation...
The incidence of type 2 diabetes mellitus (T2DM) is raising with significant associated medical complications and mortality. Bariatric surgery has shown to have beneficial metabolic effects. A model single anastomosis duodenojejunal bypass sleeve gastrectomy (SADJB-SG) was developed in a T2DM animal without obesity, Goto-Kakizaki (GK) rats, evaluate the effect procedure on glucose homeostasis. Fourteen 12-week old GK rats underwent SADJB-SG, while 11 simulated (Sham). Weight food intake were...
Hereditary angioedema (HAE) is a rare but serious condition characterized by recurrent spontaneous attacks of affecting superficial tissues upper respiratory and gastrointestinal tracts. The potentially fatal disfiguring nature HAE impacts the health-related quality life (HRQoL) patients with this condition. To assess Canadian using 36-item Short-Form Health Survey (SF-36v2). Twenty-one living in Canada over age 18 known diagnosis hereditary due to C1-INH deficiency (HAE), completed SF-36v2...
The activity of hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) varies between patients and within individual patients. Objective: This study aims develop a disease scale for C1-INH-HAE (HAE-AS) with sound measurement properties.Eleven countries participated in prospective multicenter cohort study. A clinical questionnaire was self-completed by 290 adult C1-INH-HAE. Patients also completed 2 quality life scales, the SF-36v2 HAE-QoL. Rasch analysis classic psychometric...
Background: Sexual dysfunction (SD) is one of the least studied non-motor symptoms in Parkinson’s disease (PD). Objectives: To assess sexual function a cohort patients with early-onset PD (EOPD) and compare it to group healthy controls. Methods: In this cross-sectional multicenter study, SD was assessed gender-specific multi-dimensional self-reported questionnaires: The Brief Male Function Inventory (BSFI-M) Female Index (FSFI). Scores between controls were compared associations...
Summary Background Obeticholic acid (OCA) was recently approved as the only on‐label alternative for patients with primary biliary cholangitis (PBC) intolerance or suboptimal response to ursodeoxycholic (UDCA). However, few data are available outside clinical trials. Aim To assess effectiveness and safety of OCA in a real‐world cohort non‐effective UDCA therapy. Methods Open‐label, prospective, real‐world, multicentre study, enrolling consecutive who did not meet Paris II criteria, from 18...
<i>Background:</i> Cardiovascular drugs play a major role in the pre- and postoperative care neonates with congenital heart disease. Management strategies aim to optimise contractility, improve diastolic function, maintain adequate preload, reduce afterload. Levosimendan, novel inodilator agent, enhances myocardial contractility causes peripheral coronary vasodilation. <i>Objectives:</i> A systematic approach was used evaluate acute haemodynamic effects of...