A5069805699- Aquaculture disease management and microbiota
- Animal Genetics and Reproduction
- interferon and immune responses
- MicroRNA in disease regulation
- Invertebrate Immune Response Mechanisms
- RNA and protein synthesis mechanisms
- Marine animal studies overview
- Cancer-related molecular mechanisms research
- CRISPR and Genetic Engineering
- Fish Ecology and Management Studies
- Aquaculture Nutrition and Growth
- RNA Research and Splicing
Memorial University of Newfoundland
2015-2020
Vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol) are fat-soluble secosteroid hormones obtained from plant animal sources, respectively. Fish incorporates through the diet. In mammals, D forms involved in mineral metabolism, cell growth, tissue differentiation, antibacterial immune response. is an essential nutrient aquafeeds for finfish. However, influence of on fish immunity has not yet been explored. Here, we examined effects Salmo salar primary macrophage response to A....
Piscine reovirus (PRV) has been associated with the serious disease known as Heart and Skeletal Muscle Inflammation (HSMI) in cultured Atlantic salmon Salmo salar Norway. PRV is also prevalent wild farmed without overt manifestations, suggesting multifactorial triggers or variant-specific factors are required to initiate disease. In this study, we explore head kidney transcriptome of Sockeye Oncorhynchus nerka during early infection identify host responses absence hopes elucidating...
Bacterial Kidney Disease (BKD), which is caused by a Gram-positive, intracellular bacterial pathogen (Renibacterium salmoninarum), affects salmonids including Atlantic salmon (Salmo salar). However, the transcriptome response of to BKD remained unknown before current study. We used 44K salmonid microarray platform characterise global gene expression BKD. Fish (~54 g) were injected with dose R. salmoninarum (H-2 strain, 2 × 108 CFU per fish) or sterile medium (control), and then head kidney...
Viperin is a key antiviral effector in immune responses of vertebrates including the Atlantic cod (Gadus morhua). Using cloning, sequencing and gene expression analyses, we characterized viperin at nucleotide hypothetical amino acid levels, its regulating factors were investigated. cDNA 1,342 bp long, predicted protein contains 347 acids. silico showed that composed 5 exons, as other vertebrate orthologs. In addition, radical SAM domain C-terminal sequences are highly conserved among various...