A5076676589- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Retinopathy of Prematurity Studies
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Neonatal Respiratory Health Research
- Superconducting and THz Device Technology
- Physics of Superconductivity and Magnetism
- Spine and Intervertebral Disc Pathology
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Spinal Fractures and Fixation Techniques
- Retinal and Optic Conditions
- Vascular Malformations Diagnosis and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Musculoskeletal pain and rehabilitation
- Neonatal and fetal brain pathology
- Ocular Infections and Treatments
- Dark Matter and Cosmic Phenomena
- Pediatric Pain Management Techniques
- Neonatal Health and Biochemistry
- Particle accelerators and beam dynamics
- Optical Coherence Tomography Applications
- Traumatic Ocular and Foreign Body Injuries
- Developmental Biology and Gene Regulation
Great Ormond Street Hospital for Children NHS Foundation Trust
2021-2025
Great Ormond Street Hospital
2013-2024
University College London
2013-2024
Oxford University Hospitals NHS Trust
2013-2024
Middlemore Hospital
2024
University of Oxford
2012-2023
John Radcliffe Hospital
2014-2023
University of Edinburgh
2023
Queen Victoria Hospital
2005-2020
Digestive Health Research Institute
2020
Industrial ecology is a new approach to the industrial design of products and processes implementation sustainable manufacturing strategies. It concept in which an system viewed not isolation from its surrounding systems but concert with them. seeks optimize total materials cycle virgin material finished material, component, product, waste ultimate disposal. To better characterize topic, National Academy Sciences convened colloquium were derived number salient contributions. This paper sets...
To evaluate the indications, postoperative visual efficacy, and complication rate after intraocular implantation of an iris-claw aphakic lens (IOL).Oxford Eye Hospital, Oxford, United Kingdom.Case series.This chart review comprised eyes with no capsule support that had anterior iris-fixation IOL for aphakia between 2001 2009.The study 116 (104 patients). Iris-claw IOLs were inserted during primary surgery in 18 (15.5%), exchange procedure dislocated posterior chamber 19 (16.4%), as a...
BackgroundInfant pain has immediate and long-term effects but is undertreated because of a paucity evidence-based analgesics. Although morphine often used to sedate ventilated infants, its analgesic efficacy unclear. We aimed establish whether oral could provide effective safe analgesia in non-ventilated premature infants for acute procedural pain.MethodsIn this single-centre masked trial, 31 at the John Radcliffe Hospital, Oxford, UK, were randomly allocated using web-based facility with...
To examine the morphological changes in postvitrectomy lens and to monitor development of these over time.Oxford Eye Hospital, Oxford, United Kingdom.In this prospective study, 33 consecutive phakic patients having pars plana vitrectomy were recruited. Cataract was quantified by clinical grading digital Scheimpflug image analysis. Slitlamp biomicroscopy photography used document appearance. The main outcome measures incidence, morphology, posterior subcapsular nuclear cataract.A...
In Brief Study Design. Retrospective, comparative study of clinical and radiologic outcome with independent, blinded observer. Objectives. To compare the instrumented posterolateral lumbar fusion using local bone versus autogenous iliac crest graft (ICBG). Summary Background Data. There is no published report spinal alone for degenerative disorders spine. Materials Methods. Seventy-six cases (male 26, female 50) stenosis, operated during 1996 1997 by senior author, were reviewed. All had...
Abstract The role of the midline floor plate cells in neuronal differentiation spinal cord was examined by comparing putative GABAergic neurons wildtype zebrafish embryos with those cyc‐1 mutant embryos. mutation produces a pleiotropic recessive lethal phenotype and is severe rostral brain regions, but its direct effect caudal hindbrain apparently restricted to depletion cells. In embryos, an antibody against neurotransmitter GABA labeled cell bodies, axons, growth cones three classes...
<h3>Aims</h3> To study the incidence and treatment of retinopathy prematurity (ROP) in England, 1990–2011. <h3>Methods</h3> English national Hospital Episode Statistics were analysed, for babies born hospital inpatient admissions, to obtain annual rates diagnosis of, for, with ROP. National data on low birthweight (LBW) babies, <1500 g therefore eligible ROP screening, used as denominators calculating per 1000 at risk. <h3>Results</h3> The recorded increased tenfold, from 12.8 LBW 1990...
We discuss the statistical noise associated with tunneling which is intrinsic to superconducting tunnel junctions. deduce a simple expression for in general case where probabilities may be dissimilar. The exceeds Fano-factor limited of quasiparticle creation most cases.
To investigate risk factors for retinal detachment (RD) after cataract surgery, particularly posterior capsular rupture (PCR) with or without vitreous loss.Single centre electronic medical record database study of 18 065 consecutive first eye operations performed between 2005 and 2014. Survival analysis was Kaplan-Meier curves a Cox proportional hazard regression to calculate HRs respect RD.The RD rate at 3 months 7 years 0.067% 0.30%, respectively, median time 15 (mean: months, range: 0-84...
We report for the first time, to our knowledge, acquisition of noncontact ultra-wide-field oral fluorescein angiograms in premature infants with retinopathy prematurity.High-resolution were successfully obtained 3 consecutive prematurity at Oxford Eye Hospital, Oxford, England, using Optos Panoramic 200MA imaging system (Optos PLC).Noncontact captured angiographic provide a safe and alternative method evaluating retinal vasculature prematurity.
Introduction X-linked retinoschisis (XLRS) is a potential target for gene supplementation approaches. To establish structural and functional endpoints clinical trials, comprehensive understanding of the inter-eye symmetry, relationship between parameters, disease progression vital. Methods In this retrospective multicentre study, 118 eyes 59 XLRS patients with RS1 mutations were assessed. Information from center databases included: variant; age at presentation; best-corrected visual acuity...
Purpose: To assess the rate of retinal vascularisation derived from ultra-widefield (UWF) imaging-based retinopathy prematurity (ROP) screening as predictor type 1 ROP and characterise effect anti-VEGF therapy on rate. Design: Retrospective, consecutive cohort study. Subjects: 132 eyes 76 premature infants with mean gestational age (GA) 26.0(±2.0SD) weeks birth weight (BW) 815(±264) g, who underwent longitudinal UWF imaging for screening. Setting/Venue: Level 3 neonatal unit in Oxford,...
Recent studies on the treatment of acute subretinal macular haemorrhage have shown that volume clot and time to evacuation strong prognostic factors for visual outcome. A novel technique surgical these lesions involves direct injection tissue plasminogen activator (t-PA) into haematoma using pars plana vitrectomy. The aim this study was evaluate clinical outcomes recently described procedure.17 consecutive patients with haemorrhages caused by age related degeneration were enrolled. Patient...
We have studied the dynamics of nonequilibrium state produced in single-crystal superconducting indium by pulsed laser irradiation using tunnel junctions. By a suitable choice thin metal film intimate contact with crystal, we been able to produce pronounced change time evolution excess quasiparticle density which indicates that quasiparticles are trapped film. This effect can take place both when is another superconductor lower energy gap or normal made proximity effect.
Abstract The eleven‐parameter rigid‐ion model is used to describe the lattice dynamics of GaAs. gives a satisfactory description reported neutron scattering data throughout most Brillouin zone, and critical point phonon frequencies calculated with are shown provide basis for assignment nearly all features in two‐phonon infrared spectrum second‐order Raman