A5101474843- Traditional Chinese Medicine Analysis
- Metabolomics and Mass Spectrometry Studies
- Dental materials and restorations
- Photopolymerization techniques and applications
- Ginseng Biological Effects and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Microfluidic and Bio-sensing Technologies
- Phytochemistry and Biological Activities
- Smart Grid Security and Resilience
- Lung Cancer Research Studies
- Fault Detection and Control Systems
- Flavonoids in Medical Research
- Nutrition and Health in Aging
- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Silicone and Siloxane Chemistry
- Reliability and Maintenance Optimization
- Cancer, Stress, Anesthesia, and Immune Response
- Advanced Polymer Synthesis and Characterization
- Molecular Junctions and Nanostructures
- Force Microscopy Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Chromatography in Natural Products
- Autophagy in Disease and Therapy
- Diet and metabolism studies
Xiamen University
2021-2024
Shanxi University
2014-2023
Affiliated Hospital of Southwest Medical University
2021
Beijing University of Chemical Technology
2017-2019
Shanxi Province Hospital of Traditional Chinese Medicine
2016-2019
Chongqing Institute of Green and Intelligent Technology
2015
Xuzhou University of Technology
2014
Jilin Agricultural University
2004
Astragali Radix (Huangqi), a well-known traditional Chinese medicinal plant, has been used for centuries as reinforcing vital energy herb in China. In this study, the antifatigue effect of was investigated by an 1H NMR based metabolomic approach coupled with multivariate statistical analysis. The results indicated that oral administration at dose 3 g kg−1 body weight could significantly prolong exhaustive swimming time rats, and alter serum urine metabolome. rats treated extracts showed...
Autophagy is a conserved catabolic process, which plays an important role in regulating tumor cell motility and degrading protein aggregates. Chemotherapy-induced autophagy may lead to distant metastasis even chemo-insensitivity the therapy of hepatocellular carcinoma (HCC). Therefore, vast majority HCC cases do not produce significant response monotherapy with inhibitors.In this work, we developed biomimetic nanoformulation (TH-NP) co-encapsulating Oxaliplatin (OXA)/hydroxychloroquine (HCQ,...
The repurposing of existing drugs, referred to as theranostics, has made profound impacts on precision medicine. Indocyanine green (ICG), a well-established and clinical dye, continued be star agent, described multifunctional molecule with concurrent photo- or sono-sensitiveness capabilities co-delivery accessibility, showing remarkable potential in the area unimodal multimodal imaging-guided therapy various diseases, leading extensive consideration immediate translations. In this review, we...
The thiol-epoxy/thiol-Si-methacrylate (namely polysiloxane-methacrylate) hybrid networks with systematic variations were prepared by free-radical photoinitiator (ITX) and photo-base generator (TBD·HBPh4) that induce photopolymerization. photopolymerization kinetics investigated real-time infrared spectroscopy indicated the thiol-Si-methacrylate reaction was faster more efficient than thiol-epoxy (>80% conversion in about 60 seconds 7–10 min, respectively), thiol increased an increase of...
To characterize the chemical constituents of Huanbei Zhike Prescription by ultra-high performance liquid chromatography-time flight mass spectrometry( UPLC-Q-TOF-MS/MS). A Thermo Syncronls C18 column( 2. 1 mm×100 mm,1. 7 μm) was used with methanol( A)-0. 1% formic acid solution( B) as mobile phase for gradient elution. The injection volume 2 μL; column temperature 40 ℃; flow rate 0. 3 m L·min-1; and electrospray ionization( ESI) source to collect data in positive negative ion modes. scanning...
Xueniao capsule, one of the famous traditional Chinese medicine (TCM) formulas, has been proved to be effective for treating acute pyelonephritis (APN) in clinic. However, probable mechanisms are still unclear. This study was aimed at investigating therapeutic effect and action mechanism capsule on rats. Chemical analysis four different extracts conducted by HPLC GC-MS. 21 compounds were identified obvious chemical difference also revealed among analysis. Metabolomics, combined with...
A numerical study of electroosmotic flow through microchannels has been completed in this paper. 2D Poisson-Boltzmann equation and a Navier-Stokes governing the electric double layer (EDL) field velocity cross section rectangular are numerically solved by employing SIMPLE method without use Debye-Huckel approximation. The volumetric flowrate with different aspect ratios for fixed hydraulic diameter compared. comparison simulation results show that significant influences channel cross-section...
Self-assembled composite films of APTES-GA-APTES were successfully prepared on single-crystal silicon substrates through the cross-linking reaction between glutaraldehyde (GA) and two layers 3-aminopropyltriethoxysilane (APTES). The optimal time to deposit GA layer APTES monolayer was 3 h, during which most amino groups reacted with aldehyde form smooth uniform APTES-GA films. further deposition another led generation three-layer Compared self-assembled monolayers, displayed a similar...
To screen the anti-inflammatory active fraction of unripe Forsythiae Fructus, and elucidate action mechanism, water decoction, ethyl acetate portion, n-butanol portion residue extracts Fructus were administered into rats for continuously 15 days. The acute lung injury inflammatory model was established to observe section structure tissues. Levels IL-6, TNF-α, IL-1β IL-10 in bronchoalveolar lavage fluid determined by ELISA kits, changes endogenous metabolites serum analyzed based on 1H-NMR...