Yan-Kun Yang

ORCID: 0000-0001-5123-2264
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About
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Research Areas
  • Cardiomyopathy and Myosin Studies
  • Congenital Heart Disease Studies
  • Aortic Disease and Treatment Approaches
  • Vasculitis and related conditions
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Function and Risk Factors
  • Cardiac Structural Anomalies and Repair
  • Coronary Artery Anomalies
  • Viral Infections and Immunology Research
  • Renal and Vascular Pathologies
  • Cardiovascular and Diving-Related Complications
  • Pancreatic function and diabetes
  • Atrial Fibrillation Management and Outcomes
  • Neurogenetic and Muscular Disorders Research
  • Cardiac Valve Diseases and Treatments
  • MicroRNA in disease regulation
  • Cardiac and Coronary Surgery Techniques
  • Whipple's Disease and Interleukins
  • Viral Infections and Outbreaks Research
  • Protein Kinase Regulation and GTPase Signaling
  • Cardiac electrophysiology and arrhythmias
  • Cell death mechanisms and regulation
  • Urinary Tract Infections Management
  • Cardiovascular Effects of Exercise
  • Tracheal and airway disorders

Beijing Friendship Hospital
2022

Capital Medical University
2019-2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2021

Beijing Anzhen Hospital
2019

Shanxi Province Hospital of Traditional Chinese Medicine
2019

Kyungpook National University Hospital
2017

Northeast Forestry University
2012

National Cheng Kung University
1998

Left ventricular (LV) pseudoaneurysm is a fatal and rare condition with high risk of rupture. The symptoms are nonspecific diagnosis often delayed. purpose this study to analysis series cases in our institution. Between March 2009 April 2016, 10 patients (5 males 5 females) LV were retrospectively enrolled. Clinical information, diagnostic imaging modalities, treatment, outcomes evaluated. mean age was 58.2 ± 11.0 years (28–71 years). common chest pain (3 cases), dyspnea syncope (2 cases)....

10.1097/md.0000000000006793 article EN cc-by-nc Medicine 2017-05-01

End-stage hypertrophic cardiomyopathy (HCM) is complicated by substantial adverse events. However, few studies have focused on electrocardiographic features and their prognostic values in HCM. This study aimed to evaluate the clinical manifestations value of electrocardiography patients with end-stage HCM.End-stage HCM were enrolled from a total 1844 consecutive April 2002 November 2013 at Fuwai Hospital. Clinical data, including medical history, electrocardiography, echocardiography,...

10.4103/0366-6999.157656 article EN cc-by-nc-nd Chinese Medical Journal 2015-05-26

Abstract PRKAG2 syndrome is a rare autosomal dominant inherited disorder that characterized by cardiac hypertrophy, ventricular pre-excitation and conduction system abnormalities. There little knowledge in cardiovascular magnetic resonance (CMR) characteristics of cardiomyopathy. This study investigated the genetic defect three-generation Chinese family with hypertrophy using whole-exome sequencing. A novel missense mutation, c.1006 G > T (p.V336L), was identified . mutation had not been...

10.1038/s41598-017-02455-z article EN cc-by Scientific Reports 2017-05-19

The basic helix–loop–helix (bHLH) transcription factor Ptf1a plays stage‐specific roles in the developing pancreas. During early pancreatic development, low levels of preferentially promote differentiation progenitor cells into endocrine cells, whereas high shift progenitors towards an exocrine cell fate. In adults, is essential for production enzymes by acinar cells. this paper, we show that expression repressed miR‐18a and via its binding to 3′UTR mRNA. Furthermore, overexpression exerts...

10.1016/j.febslet.2012.01.015 article EN FEBS Letters 2012-01-17

Xinfuli Granule (XG), a compound Chinese herbal medicine, has been effectively used in China for the treatment of heart failure more than fifty years. This study aimed to investigate effects and underlying mechanisms rats with doxorubicin-induced cardiotoxicity.Sprague-Dawley were treated intraperitoneal injection Doxorubicin (DOX, 2.5 mg/kg per week) six weeks, then randomly divided into four groups which received intragastrically administration normal saline (control group) or different...

10.11909/j.issn.1671-5411.2016.12.001 article EN PubMed 2016-12-01

SUMMARY Knowledge, attitudes and practices (KAP) of the population regarding severe fever with thrombocytopenia syndrome (SFTS) in endemic areas Lu'an China were assessed before after an intervention programme. The pre-intervention phase was conducted using a sample 425 participants from 12 selected villages highest rates SFTS infection. A predesigned interview questionnaire used to assess KAP. Subsequently, programme designed applied villages. KAP re-assessed for each same questionnaire....

10.1017/s0950268817002679 article EN Epidemiology and Infection 2017-11-27

Abstract Right pulmonary artery–left atrial fistula is a rare congenitalcardiac anomaly, and only few articles published so far have reported the diagnosis treatment of right fistula. In this study, we report three cases successful transcatheter closure or surgical repair

10.1017/s1047951116002523 article EN Cardiology in the Young 2016-12-12

To investigate adherence and the influence factors among patients who are on antiretrovirus therapy (ART) of 3 provinces in China.This study selected 18-year-old older AIDS as survey objects initiated anti-retrovirus between April September 2014 kept treatment for one year Yunnan,Sichuan,and Hu'nan province. Information demography, social support was collected by questionnaires. Adopt SSRS questionnaire to calculate information objective support, subjective utilization support. χ(2) test...

10.3760/cma.j.issn.0253-9624.2016.04.010 article EN PubMed 2016-04-01

It has been reported that impaired left ventricular longitudinal function may precede circumferential dysfunction in patients with coronary artery disease. This study is to determine the impact of PCI on myocardial assessed by tissue Doppler echocardiography chronic stable angina. Twenty-five consecutive angina and preserved systolic LV (EF%> 50%) underwent were studied pulsed wave at different time intervals before after PCI. All subjected following: Full history physical examination, ECG,...

10.1093/eurheartj/sur025 article EN European Heart Journal Supplements 2012-02-01

Xueniao capsule, one of the famous traditional Chinese medicine (TCM) formulas, has been proved to be effective for treating acute pyelonephritis (APN) in clinic. However, probable mechanisms are still unclear. This study was aimed at investigating therapeutic effect and action mechanism capsule on rats. Chemical analysis four different extracts conducted by HPLC GC-MS. 21 compounds were identified obvious chemical difference also revealed among analysis. Metabolomics, combined with...

10.1155/2019/6723956 article EN Evidence-based Complementary and Alternative Medicine 2019-09-03
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