A5076190767- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Emergency and Acute Care Studies
- Acute Kidney Injury Research
- Trauma Management and Diagnosis
- Central Venous Catheters and Hemodialysis
- Atherosclerosis and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Immune Response and Inflammation
- Trauma and Emergency Care Studies
- Cardiac and Coronary Surgery Techniques
- Clinical Nutrition and Gastroenterology
- Transplantation: Methods and Outcomes
- Immune cells in cancer
- Nutrition and Health in Aging
- Surgical Simulation and Training
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Simulation-Based Education in Healthcare
- Blood transfusion and management
- Neuropeptides and Animal Physiology
- Organ Transplantation Techniques and Outcomes
Prince Charles Hospital
2014-2024
Australian and New Zealand Intensive Care Society
2024
Boston Children's Hospital
2024
The University of Queensland
2012-2021
Queensland Health
2018-2020
The novel influenza A(H1N1) pandemic affected Australia and New Zealand during the 2009 southern hemisphere winter. It caused an epidemic of critical illness some patients developed severe acute respiratory distress syndrome (ARDS) were treated with extracorporeal membrane oxygenation (ECMO).To describe characteristics all A(H1N1)-associated ARDS ECMO to report incidence, resource utilization, patient outcomes.An observational study (n = 68) in 15 intensive care units (ICUs) between June 1...
Objectives To assess the capacity of intensive care units (ICUs) in Australia to respond expected increase demand associated with COVID-19. Design Analysis Australian and New Zealand Intensive Care Society (ANZICS) registry data, supplemented by an ICU surge capability survey veterinary facilities (both March 2020). Settings All ICUs facilities. Main outcome measures Baseline numbers beds, ventilators, dialysis machines, extracorporeal membrane oxygenation intravenous infusion pumps, staff...
Background and Objectives Excessive bleeding is a risk associated with cardiac surgery. Treatment invariably requires transfusion of blood products; however, the itself may contribute to postoperative sequelae. Our objective was analyse quality initiative designed provide an evidenced‐based approach management. Materials Methods A retrospective analysis compared product patient outcomes 15 months before after implementation management protocol. The protocol incorporated point‐of‐care...
Patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) frequently develop arterial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets also lead to harmful episodes of hypoxaemia. In this registry-embedded, multicentre trial, we randomly assigned adult patients VA-ECMO in an intensive care unit (ICU) either a conservative (target SaO2 92–96%) or liberal strategy 97–100%) through controlled administration via the ventilator and ECMO gas blender....
Background Fibrinogen, the major clotting protein in blood plasma, plays key roles coagulation and thrombosis. In this prospective cohort study, we measured patient's fibrinogen levels common parameters before after cardiopulmonary bypass (CPB) examined their relationships with postoperative loss. Study Design Patients undergoing cardiac surgery CPB who did not have pre-existing coagulopathy were eligible. Standard testing performed CPB. The association of these variables loss (estimated...
There is a paucity of literature pertaining to the role and techniques moulage for creating high-fidelity medical simulations. As part an Intensive Care Crisis Event Management Course, simulation extensive torso burn was desired. The aim enhance realism scenario but additionally enable chest wall escharotomy be performed.A simple step-wise technique preparing that may fitted mannequins all sizes shapes described.Utilization as overall strategy prepare mannequins' severe burns detailed.In...
Rapid response systems have been mandated for the recognition and management of deteriorating patient. Increasing medical emergency team (MET) dose may be associated with improved outcomes. Large numbers MET calls divert resources from program providing service unless additional personnel are provided. To describe implementation outcomes a multifaceted rapid system (RRS) in teaching hospital, we conducted an observational study. The RRS consisted introduction together 1) redesign ward...
Abstract Coronary artery bypass grafting (CABG) triggers a systemic inflammatory response that may contribute to adverse outcomes. Dendritic cells (DC) and monocytes are immunoregulatory potentially affected by CABG, contributing an altered immune state. This study investigated changes in DC monocyte responses CABG patients at 5 time‐points: admission, peri‐operative, ICU, day 3 5. Whole blood from 49 was used ex vivo whole culture model prospectively assess responses. Lipopolysaccharide...
Background: We established an adult extracorporeal membrane oxygenation (ECMO) service for cardiorespiratory support in April 2009. Complex therapies may show a learning curve and volume–outcome relationship. Objectives: To describe our model of care, casemix outcomes the first 30 cases together with unique features this potential strategies to manage curve. Methods: Data were obtained from intensive care unit database, medical record minutes multidisciplinary ECMO review meetings. Results:...
To detail the physiology, pathophysiology and recent advances in diagnostic analysis of cerebrospinal fluid (CSF) critical illness, briefly review pharmacokinetics pharmaco-dynamics drugs CSF when administered by intravenous intrathecal route.A articles published peer reviewed journals from 1966 to 1999 identified through a MEDLINE search on fluid.The examination has become an integral part assessment critically ill neurological or neurosurgical patient. Its greatest value lies evaluation...
Echocardiography is a key investigation in the management of patients on extracorporeal membrane oxygenation (ECMO). However, echocardiographic images are often non-diagnostic this patient population. Contrast-enhanced echocardiography may overcome many these limitations but contrast microspheres hydrodynamically labile structures prone to destruction from shear forces and turbulent flow, which exist within an ECMO circuit. This study sought evaluate microsphere (utilising signal intensity...
Complications associated with external cardiac compression include trauma to the heart, chest wall, lungs and gastrointestinal viscera, visceral injury including, ruptured stomach, liver, oesophagus, spleen colon. However, use of thrombolytics anticoagulants in patients an acute myocardial infarction increases incidence a haemorrhage when these need cardiopulmonary resuscitation. We report two out-of-hospital arrest whose immediate post-resuscitation phase was complicated by hepatic...
Objective: Lack of management guidelines for life-threatening asthma (LTA) risks practice variation. This study aims to elucidate practices LTA in the intensive care unit (ICU). Design: A retrospective cohort study. Setting: Thirteen participating ICUs Australia between July 2010 and June 2013. Participants: Patients with principal diagnosis LTA. Main outcome measures: Clinical history, ICU management, patient outcomes, ward education discharge plans. Results: Of 270 (267 patients)...