A5023098976- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Ocular Infections and Treatments
- Healthcare and Venom Research
- Biometric Identification and Security
- Medical Imaging and Analysis
- Optical Coherence Tomography Applications
University of Debrecen
2011-2025
University of Szeged
2013
Abstract This prospective cohort study is aimed to investigate circadian variations in corneal parameters, focusing on sleep-deprived subjects. Sixty-four healthy individuals (age range: 21–76 years) actively participated this study, undergoing examinations at least five times within a 24-hour timeframe. The analysis encompassed keratometric parameters of the cornea’s front (F) and back (B) surfaces, refractive power flattest steepest axes (K1, K2), astigmatism (Astig) its axis (Axis),...
We aimed to determine the effects of night-shift work on corneal parameters in thirty-five healthy individuals (24–59 years) a retrospective cohort study. Among them, 12 hospital nurses regularly worked two shifts, spending third their nights awake, whereas 23 age-matched controls never shifts and slept regularly. Measurements were performed at least five times within h. analyzed keratometric front (F) back (B) surfaces, including refractive power flattest steepest axes (K1, K2), astigmatism...
PURPOSE: To compare anterior chamber depth (ACD) measurements with a new optical device those taken standard ultrasound (US) in emmetropic phakic and pseudophakic eyes. SETTING: Department of Ophthalmology, Medical Health Science Center, University Debrecen, Hungary. METHODS: Forty-two 42 patients normal axial lengths (mean 22.91 mm ± 1.21 [SD]) were enrolled the study. The ACD was measured 3 times Scheimpflug-based Pentacam (Oculus) then A-scan US (AL-2000, Tomey). data analyzed. RESULTS:...
PURPOSE: To measure anterior chamber depth (ACD) with an segment optical coherence tomography (AS-OCT) and a standard ultrasonic (US) axial scan (A-scan) device using immersion technique to assess repeatability, reproducibility, correlations of the measurements. SETTING: Department Ophthalmology, Medical Health Science Center, University Debrecen, Hungary. METHODS: Sixty healthy eyes 41 patients were enrolled in study. The central ACD was measured 5 times AS-OCT (Visante, Carl Zeiss Meditec)...
<b><i>Purpose:</i></b> To study the association between different types of mediators in tear fluid and topographic indices characterizing severity keratoconus (KC). <b><i>Methods:</i></b> In this study, nonstimulated samples were collected from 14 eyes 11 patients with KC. The following measured by corneal topography: maximum K value, average Klyce/Maeda index (KCI), Smolek/Klyce index, opposite sector center/surround prediction standard...
Abstract Our purpose was to prospectively analyze the age-related changes of corneal Scheimpflug parameters in healthy subjects. Thirty-five eyes 35 volunteers (age 14–67 years) were investigated with an average interval 3.6 years. Changes (flattest keratometric reading at anterior (K1F) and posterior surface (K1B), steepest (K2F) surface, astigmatism, astigmatism (AstigB), flat axis (AxisB), thinnest pachymetric value (PachyMin), volume (CV10-mm)) analyzed. K1F K2F decreased significantly...
Keratoconus (KC) is the most common primary corneal ectatic disease which has considerable importance in public health. Corneal collagen crosslinking (CXL) a procedure to mitigate progression of KC and reduce demand for transplantation. Although studies have proven efficacy CXL regarding shape, none investigated effects on tear biomarkers are useful tools understand molecular mechanisms behind CXL. Our purpose was determine effect mediators patients with analyze associations changes. Tear...
The release of different cytokines and mediators in tears patients with keratoconus (KC) wearing contact lenses (CLs) may contribute to the pathology KC.Cohort study was established KC rigid gas permeable (RGP) CL (group I), ametropia silicone hydrogel (Si-Hi) II) ametropic RGP III).Our findings indicate that before wear, epidermal growth factor (EGF) tissue-type plasminogen activator (t-PA) attenuated, whereas matrix metalloproteinase (MMP)-9, interleukin (IL)-6, chemokine (C-C motif)...
To determine the reliability and repeatability of keratometry (K) measurements obtained with Pentacam high resolution (HR), automated keratometry, corneal topography systems.The right eyes 46 healthy subjects were examined prospectively. Keratometry in flat (Kf) steep (Ks) meridians taken by 2 independent investigators HR (Oculus, Wetzlar, Germany) followed keratorefractometry (KR-8100; Topcon, Tokyo, Japan), (TMS-4; Tomey, Erlangen, Germany).The mean K readings HR, 43.40/43.34 diopter (D),...
Rare interchange haplotypes in exon 3 of the OPN1LW and OPN1MW opsin genes cause X-linked myopia, color vision defect, cone dysfunction. The severity disease varies on a broad scale from nonsyndromic high myopia to blue monochromatism. Here, we describe new genotype-phenotype correlation attributed rare simultaneously present long- middle-wavelength sensitive (L- M-opsin genes).A multigenerational family with dystrophy was investigated.Affected male patients had infantile onset normal visual...
Purpose: To find immunomediator combinations which could sensitively indicate keratoconus progression.Methods: Tear samples of 42 patients with were collected at baseline and the end a one-year follow-up. The concentrations 13 mediators measured by CBA. Based on Pentacam HR examination, eyes divided into non-progressive progressive group.Results: At follow-up, significant differences observed in release IFNγ, IL-13, IL-17A, CCL5, MMP-13 PAI-1 between two groups. Changes five parameters...
Purpose To assess astigmatism induced by paired opposite clear corneal incision (OCCI) compared to single incisions and investigate factors on which its effect depends. Methods The study comprised 326 eyes from patients. In patients with <1.0 D astigmatism, was performed (CC group, n = 245), in those >1.0 preoperative a second, made (OCCI 81). Both groups consisted of superior, temporal, oblique subgroups according the steepest meridian. Prior surgery, after repeated keratometry...
To compare the concentrations of 11 tear mediators in order to reveal biochemical difference between pellucid marginal degeneration (PMD) and keratoconus (KC).We have designed a cross-sectional study which patients with corneal ectasia based on slit-lamp biomicroscopy Pentacam HR (keratometry values (K1, K2, Kmax), astigmatism, minimal radius curvature (Rmin), thickness (Apex Min), indices (surface variation, vertical asymmetry, keratoconus, central height asymmetry decentration)) were...
Purpose. To determine associations between mediators in tears the whole spectrum of keratoconus (KC); to explore connections and Scheimpflug parameters; examine correlations parameters bronchial asthma. Methods. Tear samples were collected from 69 patients 19 controls. Concentrations mediators-IL-6, -10; CXCL8, CCL5; MMP-9, -13; TIMP-1; t-PA, PAI-1-were measured by Cytometric Bead Array. Measured Pentacam include keratometry values (K 1, K 2, max), corneal thickness (Pachy Pupil, Apex, Min),...
Toric intraocular lens (IOL) implantation can be an effective method for correcting corneal astigmatism in patients with vitreoretinal diseases and cataract. Our purpose is to report the outcome of toric IOL two cases - a patient scleral-buckle-induced regular keratoconus following pars plana vitrectomy. As far as we are aware, there no reported vitrectomized eye nor astigmatism. Two myopia high underwent cataract operation after posterior segment surgery. Myopia (>2.5 diopter) were caused...
To present our results on femtosecond laser-assisted penetrating keratoplasty.Twenty-five eyes of 25 patients underwent surgery with the following indications: pseudophakic bullous keratopathy (n = 10), keratoconus 4), corneal dystrophy 5), scar band 2). Trephination both donor and recipient corneas were performed VisuMax laser device (Carl Zeiss Meditec AG, Jena, Germany). In each case, trephinaton tissue was first an artificial anterior chamber (Moria, Antony, France). For surgical plan in...