A5078690788- COVID-19 Clinical Research Studies
- Head and Neck Cancer Studies
- Cardiac Arrest and Resuscitation
- Inflammatory Myopathies and Dermatomyositis
- Airway Management and Intubation Techniques
- SARS-CoV-2 and COVID-19 Research
- Pregnancy and preeclampsia studies
- Respiratory Support and Mechanisms
- Head and Neck Surgical Oncology
- Birth, Development, and Health
- Long-Term Effects of COVID-19
- Oral health in cancer treatment
- Corneal surgery and disorders
- Thyroid and Parathyroid Surgery
- Pancreatitis Pathology and Treatment
- Systemic Lupus Erythematosus Research
- Sepsis Diagnosis and Treatment
- Skin Diseases and Diabetes
- Maternal Mental Health During Pregnancy and Postpartum
- Childhood Cancer Survivors' Quality of Life
- Parkinson's Disease and Spinal Disorders
- Consumer Attitudes and Food Labeling
- Medication Adherence and Compliance
- Pregnancy-related medical research
- Tracheal and airway disorders
St.John's Medical College Hospital
2018-2024
St. John's National Academy of Health Sciences
2019-2024
Malankara Orthodox Syrian Church Medical College Hospital
2022-2023
Queen Elizabeth Hospital
2022
The University of Adelaide
2022
Cancer Research And Biostatistics
2018
Dr. Agarwal's Eye Hospital
2017
Novem (Netherlands)
2017
Serdang Hospital
2013
PURPOSE: To describe a new technique for the treatment of keratoconus using corneal allogenic intrastromal ring segments (CAIRS). METHODS: CAIRS trephined from donor cornea double-bladed trephine were implanted into mid-depth femtosecond laser–dissected channels in patients with 6.5-mm optic zone, followed by accelerated cross-linking (A-CXL)—either conventional or contact lens–assisted CXL (A-CACXL), depending on minimum thickness. RESULTS: Twenty (24 eyes) stage 1 to 4 (Amsler–Krumeich...
Abstract Objective To evaluate the association between intakes of refined grains, whole and white rice with cardiovascular disease, total mortality, blood lipids, pressure in Prospective Urban Rural Epidemiology (PURE) study. Design cohort Setting PURE study 21 countries. Participants 148 858 participants median follow-up 9.5 years. Exposures Country specific validated food frequency questionnaires were used to assess rice. Main outcome measure Composite mortality or major events (defined as...
Introduction : Primary hyperparathyroidism (PHPT) is a common endocrine disease with variable presentation. There recent increase in the number of asymptomatic cases due to use multichannel automated analyzers. Aim To analyze changing trend PHPT patients from South India. Materials and methods We collected data on clinical presentation, biochemistry, radiological features, operative findings treated our hospital over period six years looked at differences between symptomatic PHPT. Results...
Background: Acute respiratory distress syndrome (ARDS) is characterized by dysregulated inflammation resulting in hypoxemia and failure causes both morbidity mortality.Objectives: To describe the clinical profile, outcome, predictors of mortality ARDS children admitted to Pediatric intensive care unit.Materials methods: This a single-center retrospective study conducted at tertiary referral hospital 12-bed PICU involving (1 month 18 years) with as defined Lung Injury Consensus Conference...
Emergency authorization and approval were given for the coronavirus disease-19 (COVID-19) vaccines. The efficacy reported after phase III trials 70.4% 78% Covishield Covaxin, respectively.In this study, we aim to analyze risk factors, which associated with mortality in critically ill COVID-19-vaccinated patients admitted into intensive care unit (ICU).This study was conducted from April 1, 2021 December 31, across five centers India. Patients who had received either one or two doses of any...
Background LupusPRO is a SLE specific patient reported outcomes measure developed and validated in the USA. This study aimed to validate Hindi version of systemic lupus erythematosus (SLE) patients India. Methods Disease activity damage were assessed using SELENA–SLEDAI SLICC/ACR Index respectively. Demographic clinical features recorded. The Version 36-Item Short Form Health Survey (SF-36) administered for assessment quality life. Depression, anxiety fatigue Patient Questionnaire 9 (PHQ9),...
The study aims to report late toxicities in locally advanced head-and-neck squamous cell carcinoma (LAHNSCC) treated with intensity-modulated radiation therapy (IMRT).A retrospective was conducted on 103 patients of LAHNSCC IMRT. We analyzed the cumulative incidence xerostomia, dysphagia, and aspiration at an interval 6-month, 1-year, 2-year, 3-year from start IMRT.At a median follow up 4.2 years (interquartile range, 3.5 6 years), grade ≥2 xerostomia 5.5%, dysphagia 6.9%, 11.1%. Logistic...
Hypertensive disorders of pregnancy are important causes maternal morbidity and mortality, as well preterm birth, the leading cause death for children under 5 years globally. The World Health Organization currently recommends that pregnant women receive high-dose calcium supplementation (1500-2000 mg elemental calcium) prevention preeclampsia in populations with low dietary intake. Trials low-dose (< 1000 calcium/day) during have also shown similar reductions risk preeclampsia; however, no...
Continuous positive airway pressure (CPAP) has been used in children with bronchiolitis for a long time. Currently the low-resource settings, method of providing oxygen therapy via bubble CPAP (bCPAP) to respiratory distress is not standardized and existing low-flow high mortality rate.To study effectiveness safety bCPAP as support distress.This prospective observational was conducted tertiary care pediatric intensive unit (PICU) over period 3 months. Children were administered therapy....
Optimal resuscitation measures and outcome predictors in cases of burns are not studied pediatric population, though it accounts for one the leading causes non-fatal injuries age group.We describe clinical profile children admitted with burns.This retrospective cohort study included all between 1 month 18 years to intensive care unit (PICU) from January 2015 December 2020. The total surface area (TBSA) was assessed treated as per protocol. Illness severity score (PRISM III) logistic organ...
Small-incision lenticule extraction may be associated with complications such as partial lenticular dissection, torn lenticule, adherence to cap, and sub-cap epithelial ingrowth, some of which are more likely occur during low-myopia corrections. We describe sequential segmental terminal side-cut dissection facilitate minimally traumatic smooth extraction. Anterior lamellar is followed by central posterior leaving a thin peripheral rim avoiding the side cut. This cut in manner that fixates...
The competing (noncancer) deaths have increased with aggressive treatment approach and better disease control in locally advanced head-and-neck cancer.The aim of this study is to find incidence, cause predictors early mortality cancer patients undergoing combined modality therapy.In retrospective study, a total 125 treated from January 2013 June 2017 were analyzed. number deaths, cause, the time death start therapy was recorded. To risk factors univariate multivariate logistic regression...
We report a longitudinal observational cohort of idiopathic inflammatory myositis (IIM) focusing on the long-term clinical outcome and associated parameters.
Abstract Aim Weekly low-dose cisplatin is routinely used in concurrent chemoradiation (CCRT) locally advanced head and neck cancer (LAHNC), despite 3-weekly being the standard of care. We compared compliance, toxicity efficacy weekly versus CCRT LAHNC. Materials methods In this retrospective study, 50 mg flat dose was with 100 mg/m 2 , when given LAHNC curative intent. The study outcome toxicity, loco-regional control (LRC), disease-free survival (DFS) overall (OS). Results Eighty-four...
<h3>Background</h3> The 2017 EULAR/ACR classification criteria provide a validated scoring system for the of both adult and juvenile idiopathic inflammatory myopathies (IIM) with reasonable sensitivity specificity. <h3>Objectives</h3> To assess performance criteria<sup>1</sup> in retrospective cohort IIM compare Bohan Peter criteria.<sup>2,3</sup> <h3>Methods</h3> We conducted study all patients clinically diagnosed to have tertiary care centre last ten years. Performance was assessed...
Renal histologic changes in congenital ureteropelvic junction obstruction (UPJO), although well documented, are sparsely studied children. This study aims to establish a histological grading depending on the glomerular and tubulo-interstitial hydronephrotic kidneys determine correlation with age at surgery impact function post-pyeloplasty. A renal cortical wedge biopsy was obtained after pyeloplasty were graded from 1 4. total of 47 viable biopsies 57 children showed grade 10, 2 7, 3 27, 4...
Tumor budding (TB) and poorly differentiated clusters (PDCs) are well-established prognostic factors in various cancers. This study aimed to assess the independent role of these markers endometrial carcinomas. Retrospective analysis carcinoma resection specimens by examining traditional histologic parameters. TB PDC were observed at 20× magnification ten fields invasive front categorized as present or absent. In addition, a count ≥5 was stratified “high.” Clinical follow-up details extracted...
Background: Traumatic brain injury (TBI) in children can lead to grave consequences.The mechanism, mode, and management of pediatric neurotrauma are different from adult neurotrauma, there is a growing demand study the clinicoepidemiology TBI.Objective: To explore clinicoepidemiological profile outcome neurotrauma.Methods: This single-center retrospective was conducted at tertiary referral hospital PICU involving (1 month 18 years) sustaining TBI (2012-2022).Demographic, clinical, laboratory...