Ashish Pokharel

ORCID: 0000-0002-1546-7063
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About
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Research Areas
  • Mycotoxins in Agriculture and Food
  • Child Nutrition and Water Access
  • Air Quality and Health Impacts
  • Milk Quality and Mastitis in Dairy Cows
  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Food Security and Health in Diverse Populations
  • Carcinogens and Genotoxicity Assessment
  • Child Nutrition and Feeding Issues
  • Obesity, Physical Activity, Diet
  • Global Maternal and Child Health
  • Wheat and Barley Genetics and Pathology
  • Selenium in Biological Systems
  • Food Safety and Hygiene
  • Enterobacteriaceae and Cronobacter Research
  • Listeria monocytogenes in Food Safety
  • Atmospheric chemistry and aerosols
  • Musculoskeletal Disorders and Rehabilitation
  • Health, Environment, Cognitive Aging
  • Heavy metals in environment
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Environmental Justice and Health Disparities
  • Heavy Metal Exposure and Toxicity
  • Climate Change and Health Impacts

Michigan State University
2023-2024

Helen Keller International Nepal
2017-2023

Nepal Development Research Institute
2023

Tufts University
2017-2019

Helen Keller International
2019

Recently, the United States (US) Food and Drug Administration (FDA) launched a Closer to Zero Action Plan assess risks of develop action levels for certain heavy metals in food including cadmium (Cd). The problem foodborne metal contamination has taken on new urgency, thanks part 2021 US Congressional Report detailing high found infant food. Our risk assessment aids this FDA by estimating American population's Cd exposures food, age group consumption patterns high-risk foods; determining...

10.1016/j.fct.2023.113873 article EN cc-by-nc-nd Food and Chemical Toxicology 2023-06-02

Poor nutritional status in pregnancy expressed as low mid-upper arm circumference (MUAC) is associated with birth weight. The study aims were to assess the of pregnant Ethiopian women using MUAC and examine association nutrition-specific nutrition-sensitive factors, baseline data a prospective longitudinal observational cohort conducted three rural districts Oromia region Ethiopia. Recruitment into was rolling over period nine months, used for this analysis collected while between 12–32...

10.1371/journal.pone.0214358 article EN cc-by PLoS ONE 2019-03-26

Naturally occurring aflatoxins may contribute to poor growth and nutritional statuses in children.We analyzed the relationship between contemporary lagged aflatoxin exposure 1) length-for-age z-score (LAZ); 2) length, knee-heel stunting, weight-for-age (WAZ), weight-for-length (WLZ).We conducted a longitudinal birth cohort study involving 1675 mother-infant dyads rural Nepal. Participants were repeatedly visited from pregnancy 2 years of age (2015-2019). One blood sample was collected during...

10.1093/ajcn/nqaa397 article EN cc-by-nc American Journal of Clinical Nutrition 2020-12-05

Abstract Evidence of the impact exposure to multiple mycotoxins and environment enteric dysfunction (EED) on child growth is limited. Using data from a birth cohort study, objectives this study were (a) quantify (serum aflatoxin [AFB 1 ] ochratoxin A [OTA], urinary fumonisin [UFB deoxynivalenol [DON]), as well EED (lactulose:mannitol [L:M] ratio); (b) examine potential combined effects mycotoxin growth. Multivariate regressions used identify associations between measurements (length, weight,...

10.1111/mcn.13315 article EN cc-by-nc-nd Maternal and Child Nutrition 2022-01-12

Consumption of milk is linked to improved nutrient intake and reduced risk child malnutrition in low middle-income countries. However, these benefits are contingent on the safety quality milk. Milk consumption may alleviate widespread rural Ethiopia, but milk-borne contaminants also compromise health. We aimed to: i) identify types dairy feeds used, their storage conditions, potential aflatoxin contamination; ii) assess stakeholders' knowledge about contamination along value chain; iii)...

10.1016/j.onehlt.2023.100672 article EN cc-by One Health 2024-01-02

Abstract Background Aflatoxins are found in diverse foods widely consumed worldwide. This study investigated the association between aflatoxin exposure and (a) consumption of specific foods, (b) dietary diversity (DD), (c) seasonality. Methods Women enrolled AflaCohort Study Banke, Nepal ( n = 1648) were asked how often they ate certain food items past 7 days 24 h. Serum B 1 -lysine (AFB -lys) adduct levels, measured during pregnancy, determined using high-performance liquid chromatography....

10.1038/s41430-019-0554-2 article EN cc-by European Journal of Clinical Nutrition 2020-01-02

Anemia in pregnancy is associated with higher risk of low birth weight and both maternal perinatal mortality. While previous studies Ethiopia have examined factors anemia, which are the most important determinants anemia this population remain unclear. The objective study was to examine association between status pregnant women different health, behavioral, socioeconomic Oromiya province Ethiopia.This used enrollment data from a longitudinal cohort conducted Ethiopia. Survey on household...

10.1186/s40795-017-0166-y article EN cc-by BMC Nutrition 2017-07-25

Early-childhood development (ECD) is an important determinant of a child’s cognitive ability, learning, productivity, and lifetime earnings. Animal-sourced food (ASF), which rich source high-quality protein micronutrients, has been linked with ECD outcomes. This study investigates the relationship between number, frequency, cumulative consumption ASF at 6, 9, 12, 18 months age outcomes 24 age, controlling for physical growth. The uses data collected from 701 mother–child pairs observational...

10.3390/nu15020315 article EN Nutrients 2023-01-09

Background Anemia through pregnancy is highly correlated with poor birth outcomes, especially low weight (LBW). The Nepal DHS 2011 reports prevalence of anemia in pregnant women at 48%. Objective objectives are to determine levels enrolled a longitudinal cohort and understand the factors associated serum hemoglobin. Methods Data from rolling study (n=1675 women) being conducted Banke District Nepal. At recruitment, one venous blood sample was collected each woman along anthropometry (weight,...

10.1096/fasebj.31.1_supplement.788.32 article EN The FASEB Journal 2017-04-01

A growing body of mainly cross-sectional evidence suggests an association between mycotoxins, particularly aflatoxin exposure, and poor linear growth in children. We describe the design methods a rigorous longitudinal birth cohort study aimed to deepen our understanding this hypothesized relationship validate dried blood spots as less invasive, low-cost collection method for venous samples. The AflaCohort was conducted Banke district Nepal from 2015 2019. total 1,675 pregnant women ages...

10.12691/jfs-8-1-1 article EN Journal of food security 2020-02-21

In Sidama, Ethiopia, animal-source foods can be difficult to access. Milk has important nutrients for child growth, but carries the risk of aflatoxin M1 (AFM1) contamination. AFM1 is a metabolite mycotoxin B1 (AFB1) in dairy feed; cows secrete milk when their feed contains AFB1 produced by Aspergillus fungi maize, nuts and oilseeds. It unknown whether compromises growth health. This protocol paper describes our study Sidama determine impact consumption on first 18 months life. We will...

10.1136/bmjopen-2024-084257 article EN cc-by BMJ Open 2024-04-01

Exposure to airborne particulate matter of diameter less than 2.5 microns (PM2.5) is associated with cardiovascular diseases (CVD) and chronic obstructive pulmonary disease (COPD). In agriculture, the practice tilling generates PM2.5 emissions that can jeopardize human health. This paper estimates annual deaths disability-adjusted life years (DALYs) from CVD COPD attributable corn, soybean, cotton, wheat tillage in contiguous United States. We propose a conceptual framework for an optimal...

10.2139/ssrn.4416036 preprint EN 2023-01-01

Background In Egypt, rates of child overweight and obesity are consistently increasing. While progress has been made in the reduction stunting, Egypt's rate 21% is still higher than countries region that have same GDP. Objectives The objectives were to examine understand trends variability malnutrition all its forms (over under nutrition) Egyptian children five, across time, regions socio‐economic status associated factors. Methods DHS data from 1988 2014 downloaded cleaned analyzed using...

10.1096/fasebj.31.1_supplement.649.13 article EN The FASEB Journal 2017-04-01

Background Rates of weight gain in pregnancy are associated with infant for age, length age and predictive postnatal growth at 6 months age. The study examines factors linked low mid upper arm circumference (MUAC) pregnant women Banke Nepal. Objective objectives this analysis to examine the MUAC status enrolled a longitudinal birth cohort understand MUAC. Methods Data these analyses from rolling (n=1675) being conducted 17 Village Development Committees (VDCs) District At recruitment...

10.1096/fasebj.31.1_supplement.960.10 article EN The FASEB Journal 2017-04-01

Stunting and wasting in early life increase the risk of mortality. While assessed diagnosed as individual conditions, these two forms malnutrition often coexist within same populations possibly individual. The main objective our analysis was to assess magnitude stunting among Nepali infants first 12 months investigate association on later stunting. For this analysis, we utilized anthropometric data collected a longitudinal birth cohort study with 1675 maternal-infant dyads. Birth length...

10.1093/cdn/nzz034.p10-002-19 article EN cc-by-nc-nd Current Developments in Nutrition 2019-06-01
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