A5000852688- Metal complexes synthesis and properties
- Vanadium and Halogenation Chemistry
- Free Radicals and Antioxidants
- Metal-Catalyzed Oxygenation Mechanisms
- X-ray Diffraction in Crystallography
- Crystal structures of chemical compounds
- Crystallization and Solubility Studies
- Magnetism in coordination complexes
- Protein Interaction Studies and Fluorescence Analysis
- Lanthanide and Transition Metal Complexes
- Organometallic Compounds Synthesis and Characterization
- Electrochemical Analysis and Applications
- Synthesis and biological activity
- Cassava research and cyanide
- Enzyme function and inhibition
- Trace Elements in Health
- Inorganic and Organometallic Chemistry
- Computational Drug Discovery Methods
- Synthesis and Characterization of Heterocyclic Compounds
- Molecular Sensors and Ion Detection
- Phytochemicals and Antioxidant Activities
- Alkaline Phosphatase Research Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Metal-Organic Frameworks: Synthesis and Applications
- Nonlinear Optical Materials Research
Universidad Nacional de La Plata
2016-2025
Consejo Nacional de Investigaciones Científicas y Técnicas
2016-2025
Ottawa Hospital
2024
Royal Society of Chemistry
2024
Centre National pour la Recherche Scientifique et Technique (CNRST)
2024
Johns Hopkins All Children's Hospital
2024
Johns Hopkins University
2024
Centro Científico Tecnológico - La Plata
2019-2020
Instituto de Física La Plata
2019
University of Huddersfield
2005
Flavonoids, a polyphenolic compound family, and the vanadium compounds have interesting biological, pharmacological, medicinal properties. We report herein antitumor actions of complex [VO(chrysin)2EtOH]2 (VOchrys) on MG-63 human osteosarcoma cell line. Oxovanadium(IV), chrysin VOchrys caused concentration-dependent inhibition viability. The was strongest antiproliferative agent (p < 0.05). Cytotoxicity genotoxicity studies also showed concentration effect. Reactive oxygen species (ROS)...
Abstract The thrombin receptor was the first cloned G protein–coupled reported to be activated by proteolytic cleavage of its extracellular amino terminus. A second proteinase-activated (PAR-2) recently and expressed in Xenopus laevis oocytes. PAR-2 trypsin a peptide (SLIGRL) derived from new Since mRNA detected highly vascularized organs, we compared physiological functions vascular endothelium. Thrombin both elicited endothelium-dependent relaxations prostaglandin F 2α (PGF )–contracted...
Intracerebroventricular (ICV) administration of neuropeptide Y (NPY) has been shown to decrease energy expenditure, induce hypothermia, and stimulate food intake. Recent evidence suggested that the Y5 receptor may be a significant mediator NPY-stimulated feeding. The present study attempts further characterize role NPY Y5-receptor subtypes in feeding expenditure regulation. Satiated Long-Evans rats with temperature transponders implanted interscapular brown adipose tissue (BAT) displayed...
DNA from neoplastic hepatic tissues of feral fish environmentally exposed to carcinogens was shown contain the guanine-derived lesion 2,6-diamino-4-hydroxy-5-formamido-pyrimidine (FapyGua). This modification appears arise attack hydroxyl radical at C-8 guanine. Concentrations ranged 0.97 5.11 nmol/mg DNA. FapyGua not detected in non-neoplastic tissue and has been previously reported occur animal tissues. The present findings support view that reactive oxygen species damage living systems...
A new Cu(II) complex with the antihypertensive drug telmisartan, [Cu8Tlm16]·24H2O (CuTlm), was synthesized and characterized by elemental analysis electronic, FTIR, Raman electron paramagnetic resonance spectroscopy. The crystal structure (at 120 K) solved X-ray diffraction methods. octanuclear is a hydrate of but otherwise isostructural to previously reported [Cu8Tlm16] complex. crystallizes in tetragonal P4/ncc space group = b 47.335(1), c 30.894(3) Å, Z 4 molecules per unit cell giving...