- Environmental Toxicology and Ecotoxicology
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Marine Bivalve and Aquaculture Studies
- Heavy metals in environment
- Toxic Organic Pollutants Impact
- Marine Biology and Environmental Chemistry
- Physiological and biochemical adaptations
- Mercury impact and mitigation studies
- Aquatic Invertebrate Ecology and Behavior
- Calcium Carbonate Crystallization and Inhibition
- Pharmaceutical and Antibiotic Environmental Impacts
- Nanoparticles: synthesis and applications
- Microplastics and Plastic Pollution
- Ion channel regulation and function
- Aquaculture Nutrition and Growth
- Effects and risks of endocrine disrupting chemicals
- Analytical chemistry methods development
- Pesticide and Herbicide Environmental Studies
- Chromium effects and bioremediation
- Ocean Acidification Effects and Responses
- Autophagy in Disease and Therapy
- Pesticide Exposure and Toxicity
- Carcinogens and Genotoxicity Assessment
- Electrochemical Analysis and Applications
National Research Council
2020-2021
University of Plymouth
2015-2021
Mario Negri Institute for Pharmacological Research
2017-2020
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2020
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2010-2019
Innovation Engineering (Italy)
2016
Royal Cornwall Hospital
2015
University of Exeter
2015
Institute of Structure of Matter
2013
Azienda Sanitaria Locale Alessandria
1998-2009
Metallothionein (MT) is a sulfhydryl-rich protein involved mainly in heavy metal homeostasis and detoxification. In this study, the use of mussel as an experimental model allowed us to test MT antioxidant properties at molecular, cellular, organism level. induction was achieved by exposure Cd (200 μg/l) aquaria for 7 days followed detoxification sea 28 days. Cd-preexposed nonexposed mussels were then treated with Fe (300–600 3 Biochemical assays on digestive gland tissue showed that...
Biomarkers on sentinel organisms are utilised worldwide in biomonitoring programs. However, the lack of effective interpretational capacity has hampered their uptake for use assessment risk environmental management. The aim present study was to develop and test an objective decision-support or expert system capable integrating biomarker results into a five-level health-status index. is based set rules derived from available data responses natural contaminant-induced stress marine mussels....
The risk posed by complex chemical mixtures in the environment to wildlife and humans is increasingly debated, but has been rarely tested under environmentally relevant scenarios. To address this issue, two of 14 or 19 substances concern (pesticides, pharmaceuticals, heavy metals, polyaromatic hydrocarbons, a surfactant, plasticizer), each present at its safety limit concentration imposed European legislation, were prepared for their toxic effects. effects assessed 35 bioassays, based on 11...
Biodegradable plastics are mostly applied in packaging materials (e.g. shopping bags), waste collection bags, catering products, and agricultural applications. In this last case, degradation takes place directly soil where biodegradable plastic products intentionally left after use mulch films for weeds control). Due to the growing volumes of polymers plastics, interest their environmental safety is increasing more research carried out. Some attempt has been made apply biotests, used other...
Heavy metals are stable and persistent environmental contaminants. The range of metal concentrations is generally below acute thresholds in coastal areas, where recognition chronic sublethal effects more relevant. Evidence long-term adverse effects, such as cancer, due to heavy marine animals comes from a number field experimental studies. mechanism carcinogenicity remains largely unknown, although several lines evidence suggest that genotoxic effect may be involved. aim our study was...