A5017547033- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical studies and practices
- Respiratory and Cough-Related Research
- Mast cells and histamine
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Pediatric health and respiratory diseases
- Chemotherapy-related skin toxicity
- Advanced Biosensing Techniques and Applications
- Photodynamic Therapy Research Studies
- Olfactory and Sensory Function Studies
- Acute Kidney Injury Research
- Digital Innovation in Industries
- Photoacoustic and Ultrasonic Imaging
- Biosimilars and Bioanalytical Methods
- Dental Anxiety and Anesthesia Techniques
- Obstructive Sleep Apnea Research
- Eosinophilic Disorders and Syndromes
- Electronic Health Records Systems
Université de Montpellier
2016-2025
Centre Hospitalier Universitaire de Montpellier
2016-2025
Hôpital Arnaud de Villeneuve
2016-2025
Inserm
2012-2024
Sorbonne Université
2014-2023
Institut Universitaire de Recherche Clinique
2020-2023
Sorbonne Paris Cité
2022
Institut Pierre Louis d‘Épidémiologie et de Santé Publique
2014-2021
Université Paris Cité
2017-2019
UPMC Health System
2018
To cite this article: Bousquet J, Heinzerling L, Bachert C, Papadopoulos NG, PJ, Burney PG, Canonica GW, Carlsen KH, Cox Haahtela T, Lodrup KC, Price D, Samolinski B, Simons FER, Wickman M, Annesi‐Maesano I, Baena‐Cagnani CE, Bergmann Bindslev‐Jensen Casale TB, Chiriac A, Cruz AA, Dubakiene R, Durham SR, Fokkens WJ, Gerth‐van‐Wijk Kalayci O, Kowalski ML, Mari Mullol Nazamova‐Baranova O’Hehir RE, Ohta K, Panzner P, Passalacqua G, Ring Rogala Romano Ryan Schmid‐Grendelmeier Todo‐Bom Valenta...
Abstract A recent survey of the European Academy Allergy and Clinical Immunology (EAACI) Drug Interest Group (DAIG) on how allergy specialists deal with beta‐lactam (BL) hypersensitivity demonstrated a significant heterogeneity in current practice, suggesting need to review update existing EAACI guidelines order make diagnostic procedures as safe accurate, but also cost‐effective, possible. For this purpose, bibliographic search large studies regarding BL diagnosis was performed by an task...
In drug hypersensitivity, provocation testing (DPT), also called challenge, is the gold standard for investigation. recent years, risk stratification has become an important tool adjusting diagnostic strategy to perceived risk, whilst still maintaining a high level of safety patient. Skin tests are recommended before DPT but may be omitted in low-risk patients. The task force suggests strict definition such patients children and adults. Based on experience evidence from studies allergy...
Immediate and nonimmediate hypersensitivity reactions to iodinated contrast media (ICM) have been reported occur in a frequency of about 0.5%-3% patients receiving nonionic ICM. The diagnosis management these vary among guidelines published by various national international scientific societies, with recommendations ranging from avoidance or premedication drug provocation test. This position paper aims give for the ICM analyze controversies this area. Skin tests are recommended as initial...
Chemotherapeutic drugs have been widely used in the treatment of cancer disease for about 70 years. The development new treatments has not hindered their use, and oncologists still prescribe them routinely, alone or combination with other antineoplastic agents. However, all chemotherapeutic agents can induce hypersensitivity reactions (HSRs), different incidences depending on culprit drug. These are third leading cause fatal drug-induced anaphylaxis United States. In Europe, deaths related...
Drug provocation tests (DPT) are commonly performed as part of β-lactam (BL) allergy workup, in case negative skin (ST) and the absence contraindications. The recommendations learned societies have created a frame for DPT performance, but protocols vary widely between centres, generating various hypothesis-driven (i.e. empirical dosing, driven by both safety concerns practical aspects).The primary objective this retrospective analysis was to detect eliciting dose thresholds (reactive doses)...
Peach is a common elicitor of food allergic reactions. Peach-induced immediate reactions may occur as benign pollen-food syndromes, usually due to birch pollen-related PR-10 cross-reactivity in temperate climates, and potentially severe primary allergies, predominantly related nsLTP Pru p 3 Mediterranean regions. The newly described peach allergen 7 has gained recent attention potential allergy severity marker. Sensitization its allergenic homologues the gibberellin-regulated protein family...
BackgroundNeuromuscular blocking agents (NMBAs) are among the leading cause of perioperative anaphylaxis, and most these reactions IgE mediated. Allergic sensitisation induced by environmental exposure to other quaternary ammonium-containing compounds, such as pholcodine, has been suggested. The aim this study was assess relationship between pholcodine NMBA-related anaphylaxis.MethodsALPHO a multicentre case-control study, comparing within year before anaesthesia patients with anaphylaxis...
An accurate diagnosis of β-lactam (BL) allergy can reduce patient morbidity and mortality. Our aim was to investigate the availability BL reagents, their use test procedures in different parts Europe, as well any differences diagnostic workups for evaluating subjects with hypersensitivity. A survey emailed all members EAACI Drug Allergy Interest Group (DAIG) between February April 2016, questionnaire meant study management suspected The 82 DAIG centres answered by 57. Amoxicillin alone or...
β-lactam antibiotics are associated with a variety of immune-mediated or hypersensitivity reactions, including immediate (type I) reactions mediated by antigen-specific IgE.We sought to identify genetic predisposing factors for antibiotics.Patients clinical history either penicillins cephalosporins, which were immunologically confirmed, recruited from allergy clinics. A genome-wide association study was conducted on 662 patients (the discovery cohort) diagnosis and the main finding...
Patients with a penicillin allergy label have an increased risk of surgical site infection. Although decision tree was published in 2019 to define which patients could benefit from direct cephalosporin use the perioperative setting, this strategy remains unvalidated. This consensus statement aimed adapt it based on expert cover persisting caveats and environment poor allergist resources. Perioperative antibiotic prophylaxis experts were invited participate. The Delphi method implemented...
To cite this article : Masse MS, Granger Vallée A, Chiriac Dhivert‐Donnadieu H, Bousquet‐Rouanet L, Bousquet P‐J, Demoly P. Comparison of five techniques skin prick tests used routinely in Europe. Allergy 2011; 66 1415–1419. Abstract Background: Skin represent indispensable tools allergy, even more than 30 years after their introduction clinical practice. Objectives: Few recent European studies have focused on topic and we thus wanted to compare the instruments most often today. Methods:...
Abstract Background Non‐steroidal anti‐inflammatory drugs (NSAIDs) are the main cause of drug‐induced hypersensitivity in children. Many classifications have been proposed, focusing on adults. So far, no large study has deeply investigated a pediatric cohort. The aim present was to describe population NSAID hypersensitive patients reporting reaction during their childhood and verify whether it is possible classify patients, following EAACI / ENDA classification. Methods We conducted...
Drug provocation tests (DPTs) are often needed when evaluating patients with suspected drug hypersensitivity reactions. General considerations on DPTs, regard to indications, contraindications, methods, limitations and interpretations have been thoroughly addressed various protocols published. However, the field of allergy is changing DPTs make no exception. Novel (or sometimes, simply renewed) approaches arise, awaiting be either validated or refuted in larger studies future. Instead...