A5046102768- Anesthesia and Pain Management
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Musculoskeletal pain and rehabilitation
- Pain Management and Placebo Effect
- Pediatric Pain Management Techniques
- Rheumatoid Arthritis Research and Therapies
- Nausea and vomiting management
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal synovial abnormalities and treatments
- Anesthesia and Sedative Agents
- Gastrointestinal motility and disorders
- Thermoregulation and physiological responses
- Diversity and Career in Medicine
- Dental Anxiety and Anesthesia Techniques
- Health and Medical Research Impacts
- Total Knee Arthroplasty Outcomes
- Lymphoma Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Gastroesophageal reflux and treatments
- Neurological and metabolic disorders
- Treatment of Major Depression
- Patient Safety and Medication Errors
- Diet and metabolism studies
Copenhagen University Hospital
2006-2025
Hvidovre Hospital
2025
Rigshospitalet
2006-2019
Frederiksberg Hospital
2018
University of Copenhagen
2015
Center for Rheumatology
2014
Centre for Sight
2012
Gentofte Hospital
2011
Herlev Hospital
2006-2009
Glostrup Hospital
2006
<h3>Objectives</h3> To investigate the relation between ankylosing spondylitis disease activity score (ASDAS), Bath index (BASDAI) and treatment response biomarkers of inflammation (C-reactive protein (CRP), interleukin-6 (IL-6), YKL-40), angiogenesis (vascular endothelial growth factor (VEGF)), cartilage (C-terminal crosslinking telopeptide type II collagen (CTX-II), matrix metalloproteinase-3 (MMP-3), total aggrecan, oligomeric protein) bone I collagen, osteocalcin) turnover in 60 patients...
MRI-scores of synovial membrane hypertrophy and bone erosions the RA-wrist are introduced.Gadolinium-DTPA enhanced magnetic resonance imaging (MRI) conventional radiography (CR) wrist were performed in 16 patients with rheumatoid arthritis (RA) 3 healthy controls.A MRI-score was obtained by summation gradings 6 regions wrist. The score significantly higher wrists than without clinical signs active arthritis. 0 all controls. Each assessed MRI CR respect to erosions. Bone detected 14 contrast...
Background: The aim of the present study was to investigate whether a combination rofecoxib and gabapentin could improve pain relief reduce opioid requirements, compared with alone, during first 5 days after tonsillectomy. Methods: In randomized, double‐blind, placebo‐controlled study, 49 patients received 1200 mg pre‐operatively, followed by 2 × 600 on day operation 3 for next days, or placebo. Both groups were given 50 daily. post‐operative care unit, intravenous morphine administered in...
Background: The purpose of the present study was to measure incidence and type incidents that occurred in relation anaesthesia surgery during a 1‐year period six Danish hospitals. Furthermore, we wanted identify risk factors for incidents, as well being deemed critical. Methods: A four‐page questionnaire describing patient data, surgery, occurrence filled all anaesthesias period, subsequently processed. incident reporting form incorporated 59 predefined adverse events. one or more these...
Introduction Clinical pain models can be applied when investigating basic physiologic responses in healthy volunteers. Several exist; however, only few have been adequately validated. Our primary aim with this prospective study was to investigate the intra- and inter-individual variation secondary hyperalgesia elicited by brief thermal sensitization (45°C for 3 min) Material Methods Fifty volunteers were included. Areas of following investigated 2 observers on 4 experimental days, a minimum...
Introduction Central sensitization plays a pivotal role in maintenance of pain and is believed to be intricately involved several chronic conditions. One clinical manifestation central secondary hyperalgesia. The degree hyperalgesia presumably reflects individual levels sensitization. objective this study was investigate the association between areas volumes caudate nuclei other brain structures processing. Materials methods We recruited 121 healthy male participants; 118 were included final...
Introduction: The area of secondary hyperalgesia following brief thermal sensitization (BTS) the skin and heat pain detection thresholds (HPDT) may both have predictive abilities in regards to sensitivity clinical states. association between HPDT hyperalgesia, however, remains unsettled, dissimilarities physiologic properties suggest that they represent 2 distinctively different entities. aim this study was investigate BTS-induced hyperalgesia. Methods: A sample 121 healthy male participants...
Several factors are believed to influence the development and experience of pain. Human clinical pain models central tools, in investigation basic physiologic responses, can be applied patients as well healthy volunteers. Each model investigates different aspects human response. Brief thermal sensitization induces a mild burn injury, resulting primary hyperalgesia at site stimulation, secondary surrounding stimulation. Central is play an important role hyperalgesia; however, possible...
Background: Experience and development of pain may be influenced by a number physiological, psychological, psychosocial factors. In previous study we found differences in neuronal activation to noxious stimulation, microstructural neuroanatomical differences, when comparing healthy volunteers with size the area secondary hyperalgesia following standardized burn injury. Objective: We aim investigate degree association between volume pain-relevant structures brain brief thermal sensitization....
<h3>Background</h3> Adherence to Methotrexate has been reported be weak in patients with rheumatoid arthritis. <h3>Objectives</h3> To study adherence methotrexate (MTX) and factors of importance thereof. arthritis (RA). <h3>Methods</h3> Danish Nationwide cohort study. All a hospital diagnosis RA (ICD10 codes M05.X, M06.X) after January 1, 1997 aged ≥18 years at the date first diagnosis/contact, least one prescription MTX (L04AX03) were included. avoid prevalent cases only those time 1998...