Hong Lin

ORCID: 0000-0002-1582-0277
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About
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Research Areas
  • Advanced Photocatalysis Techniques
  • TiO2 Photocatalysis and Solar Cells
  • Mosquito-borne diseases and control
  • Malaria Research and Control
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Viral Infections and Vectors
  • Vector-borne infectious diseases
  • Catalytic Processes in Materials Science
  • Quantum Dots Synthesis And Properties
  • HER2/EGFR in Cancer Research
  • Immune Cell Function and Interaction
  • Microbial Natural Products and Biosynthesis
  • Blood donation and transfusion practices
  • Monoclonal and Polyclonal Antibodies Research
  • Rabies epidemiology and control
  • Liver Disease Diagnosis and Treatment
  • Bacteriophages and microbial interactions
  • Genomics and Phylogenetic Studies
  • T-cell and B-cell Immunology
  • Viral-associated cancers and disorders
  • Lymphoma Diagnosis and Treatment
  • Travel-related health issues
  • Hemoglobinopathies and Related Disorders
  • Electronic and Structural Properties of Oxides

Jiangsu Province Blood Center
2012-2022

Sun Yat-sen University
2017

Fifth Affiliated Hospital of Sun Yat-sen University
2017

Peking University
2015

Nanjing Medical University
2011-2013

Jiangsu Provincial Hospital of Traditional Chinese Medicine
2013

Huadong Hospital
2013

Huadong Medical Institute of Biotechniques
2013

Michigan United
2011

Van Andel Institute
2011

Anatase TiO2 nanoparticles with average particle size ranging between 12 and 23 nm were synthesized by metalorganic chemical vapor deposition. The structure determined x-ray diffraction transmission electron microscopy. specific surface areas measured Brunauer-Emmett-Teller ranged from 65 to 125m2∕g. effects on the stability of in air studied for isochronally annealed samples temperature range 700–800 °C. Only anatase rutile phase transformation occurred. With decrease initial onset...

10.1063/1.1807520 article EN Journal of Applied Physics 2004-11-22

We have determined the electronic and atomic structure of N doped TiO2 using a combination hard x-ray photoelectron spectroscopy first-principles density functional theory calculations. Our results reveal that doping leads to formation oxygen vacancies both impurity accounts for observed visible light catalytic behavior TiO2.

10.1063/1.3272272 article EN Applied Physics Letters 2009-12-28

Undoped and Nd3+-doped TiO2 nanoparticles were synthesized by chemical vapor deposition in order to tailor the band gap of TiO2. The doping reduced gap. was measured ultraviolet-visible light absorption experiments near-edge x-ray fine structure. maximum reduction 0.55 eV for 1.5 at. % Nd-doped nanoparticles. Density functional theory calculations using generalized gradient approximation with linearized augmented plane wave method used interpret narrowing. narrowing primarily attributed...

10.1063/1.1627962 article EN Applied Physics Letters 2003-11-15

Human trophoblastic cell surface antigen 2 (Trop2) has been suggested as an oncogene, which is associated with the different types of tumors. In this study, a human Fab antibody against Trop2 extracellular domain was isolated from phage library by display technology, and characterized ELISA, FACS, fluorescence staining Western blotting analysis. MTT, apoptosis assay wound healing were employed to evaluate inhibitory effects on breast cancer growth in vitro, while tumor-xenograft model vivo....

10.1002/ijc.28451 article EN International Journal of Cancer 2013-08-26

Two new peptaibols, namely microbacterins A (1) and B (2), were isolated from the deep sea inhabited actinomycete Microbacterium sediminis spp. nov. YLB-01(T). The sequences of amino acid residues determined on basis intensive NMR ESI-MS/MS spectroscopic analysis, in addition to Marfey's method CD optical rotation data for configurational assignment. Both 1 2 exhibited significant cytotoxic activities against a panel human tumor cell lines.

10.1021/acs.orglett.5b00172 article EN Organic Letters 2015-02-12

The present study aimed to investigate the prevalence of fatigue and determine factors associated with in female medical personnel. Based on a cross-sectional study, total 1608 personnel at 54 hospitals Zhuhai, China were recruited by multistage stratified cluster sampling method. Symptoms Checklist-90-Revised Chalder Fatigue Scale used assess psychiatric symptoms fatigue, respectively. Data regarding demographic, health, work related variables also collected. Multivariate logistic...

10.1080/13548506.2017.1361038 article EN Psychology Health & Medicine 2017-08-04

Abstract Background Alpha B-crystallin (αB-crystallin) has been suggested to play an important role in the development of solid tumors. However, association between αB-crystallin expression and clinicopathological characteristics human laryngeal carcinoma is not well defined. This study aimed examine squamous cell (LSCC) investigate relationship its prognosis LSCC. Methods Real-time polymerase chain reaction (six LSCC samples, six tumor-adjacent normal samples) immunohistochemistry by tissue...

10.1186/1756-9966-31-101 article EN cc-by Journal of Experimental & Clinical Cancer Research 2012-12-01

Latent membrane protein (LMP) 1 and LMP2A encoded by Epstein-Barr virus (EBV) are associated with the development of malignancies, but their expression in extranodal NK/T-cell lymphoma, nasal type (ENKTL) relationship clinical characteristics this disease remain poorly understood. In present study, we examined LMP1 ENKTL, investigated correlations between clinicopathological ENKTL patients.Paraffin sections surgically removed samples from 16 patients were analyzed immunohistochemistry...

10.1186/1746-1596-7-178 article EN cc-by Diagnostic Pathology 2012-12-01

Background Malaria is a global public health problem. China has had no case of indigenous malaria since 2016. However, imported cases remain an issue among travelers, overseas workers, and foreign traders. Although these are always asymptomatic, if they donate blood, there great risk transfusion transmitted-malaria (TTM). Therefore, blood banks need rapid screening tool to detect Plasmodium species. Methods We designed assay using recombinase-aided amplification (RAA) lateral-flow dipstick...

10.3389/fcimb.2022.922146 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-06-24

<b><i>Objective:</i></b> In 2010, only 1 donor blood sample was found to be anti-hepatitis C virus (HCV) negative and HCV RNA positive, as detected by nucleic acid testing. occult infection (OCI), is in peripheral mononuclear cells (PBMCs). We investigated the prevalence of OCI among donors. <b><i>Methods:</i></b> collected 513 samples from 334 eligible 179 deferred donors, including 55 anti-HCV-positive, 113 alanine aminotransferase...

10.1159/000455854 article EN Intervirology 2016-01-01

Nitrogen-doped TiO2 nanoparticles were synthesized via plasma assisted metal organic chemical vapor deposition. Nitrogen dopant concentration was varied from 0to1.61at.%. The effect of nitrogen ion doping on visible light photocatalysis has been investigated. Samples analyzed by various analytical techniques such as x-ray diffraction, transmission electron microscopy, photoelectron spectroscopy, and near-edge absorption fine structure. Titanium tetraisopropoxide used the titanium precursor,...

10.1116/1.2192544 article EN Journal of Vacuum Science & Technology B Microelectronics and Nanometer Structures Processing Measurement and Phenomena 2006-04-24

Hepatitis B infections, characterized by the presence of a viral genome without detectable hepatitis surface antigen (HBsAg; Occult infection [OBI]), have been reported recently.We performed serological and molecular characterization OBI among blood donors at Jiangsu province center during years 2013 2014.All donor samples were routinely screened double enzyme-linked immunosorbent assay (ELISA) for C virus (HCV), (HBV), human immunodeficiency (HIV), Treponema pallidum (TP), alanine...

10.5812/hepatmon.40492 article EN Hepatitis Monthly 2016-10-02

Hydrogen is among several energy sources that will be needed to replace the quickly diminishing fossil fuels. Free hydrogen not available naturally on earth and current processes require a fuel, methane, generate hydrogen. Electrochemical splitting of water titania proposed by Fujishima suffers from low efficiency. The efficiency could enhanced if full sun spectrum can utilized. Using pulsed laser deposition technique we synthesized nitrogen doped titanium dioxide (TiO2−xNx) thin films with...

10.1063/1.3428514 article EN Journal of Applied Physics 2010-06-15

Recombinant antibody phage display technology has been used to mimic many aspects of the processes that govern generation and selection high-affinity natural human antibodies in immune system, especially for infectious disease prophylaxis. An anti-rabies virus immunized phage-display Fab library was constructed from peripheral blood lymphocytes vaccinated volunteers. The library, with a diversity 6.7×10(8), select produce bound rabies glycoprotein. After five rounds immobilized fixed virion...

10.1371/journal.pone.0019848 article EN cc-by PLoS ONE 2011-05-09

Melanoma-associated antigen (MAGE) is expressed on the surface of multiple tumor cell types and a promising target biotherapeutic drug delivery via anti-MAGE-A1 antibody. In this study, human single-chain variable fragment (scFv) antibody phage library was generated applied to recombinant MAGE-A1-coated immunotubes by display technology. The soluble anti- MAGE-A1 scFv purified immobilized metal-chelated affinity chromatography (IMAC). could bind native confirmed enzyme-linked immunosorbent...

10.2174/18715206113139990134 article EN Anti-Cancer Agents in Medicinal Chemistry 2013-09-01

Introduction Severe fever with thrombocytopenia syndrome (SFTS) has become a global threat to public health since its first report in China 2009. However, the pathogenesis of SFTS virus (SFTSV) humans remains unclear. Also, there are no effective therapeutics for SFTS. Cyclophilin A (CyPA) regulates protein folding and trafficking involved various viral infectious diseases, but role SFTSV infection not been elucidated. Methods We detected plasma CyPA levels 29 healthy subjects 30 patients by...

10.3389/fmicb.2022.1046176 article EN cc-by Frontiers in Microbiology 2022-12-01
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