A5101718655- Nanoplatforms for cancer theranostics
- Dam Engineering and Safety
- Ultrasound and Hyperthermia Applications
- Luminescence and Fluorescent Materials
- Hydraulic flow and structures
- Gut microbiota and health
- Polymer Nanocomposites and Properties
- Geotechnical Engineering and Analysis
- Aquatic and Environmental Studies
- Protein Degradation and Inhibitors
- Crystallization and Solubility Studies
- Asymmetric Synthesis and Catalysis
- Ovarian cancer diagnosis and treatment
- Photoacoustic and Ultrasonic Imaging
- Polymer crystallization and properties
- Organoboron and organosilicon chemistry
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Nanocluster Synthesis and Applications
- Vitamin D Research Studies
- Periodontal Regeneration and Treatments
- Lanthanide and Transition Metal Complexes
- biodegradable polymer synthesis and properties
- Peptidase Inhibition and Analysis
- Advanced Nanomaterials in Catalysis
Shanghai Institute of Materia Medica
2023-2025
Chinese Academy of Sciences
2001-2024
University of Chinese Academy of Sciences
2024
Northwest A&F University
2018-2019
Xi'an University of Technology
2018
State Key Laboratory of Polymer Physics and Chemistry
2001
Institute of Chemistry
2001
Due to the wide application of reporter gene-related visible/NIR-I bioluminescent imaging, multiplexed fluorescence imaging across visible/NIR-I/NIR-II has excellent potential in biomedical research. However, vivo applications those regions have rarely been reported due lack proper fluorophores. Herein, nine squaraine dyes, which exhibit diverse adsorption and emission wavelengths, were synthesized. Among them, water-soluble SQ 710–5k 905 found significant absorption differences, allowed...
ADVERTISEMENT RETURN TO ISSUECommunication to the...Communication the EditorNEXTA Study of Physical Aging in Semicrystalline Poly(ethylene terephthalate) via Differential Scanning CalorimetryJ. Zhao, R. Song, Z. Zhang, X. Linghu, Zheng, and Q. FanView Author Information State Key Laboratory Polymer Physics & Chemistry, Center for Molecular Science, Institute Chinese Academy Sciences, Beijing 100080, P. China Cite this: Macromolecules 2001, 34, 3, 343–345Publication Date (Web):January 5,...
Cu(i)-Catalyzed diastereoselective carboboration of α-alkyl-substituted α,β-unsaturated carboxylic esters to produce β-boryl-α-quaternary carbon was developed. The skeletons dialkyl sulfates, primary allyl halides, and benzyl bromides were transferred the α-position substrates provide products in moderate good yields with a diastereoselectivity >95% most cases. Substrates bearing β-(hetero)aryl substituent gave higher diastereoselectivities than those linear β-alkyl substituent. crystal...
In recent studies, combinations of histone deacetylases (HDACs) inhibitor with kinase showed additive and synergistic effects. BRafV600E as an attractive target in many diseases treatments has been studied extensively. Herein, we present a novel design approach though incorporating the pharmacophores HDACs one molecule. Several synthesized compounds exhibited distinct HDAC1 inhibitory activities. The representative dual Raf/HDAC inhibitor, 7a, better antiproliferative activities against A549...
Follicular tracking is typically conducted using ultrasound technology, but its effectiveness constrained by limited resolution. High-resolution imaging of deep tissues can be accomplished luminescence in the near-infrared II window (NIR-II, 1000-1700 nm); however, contrast agents that are used lack specificity. Here, it reported FDA-approved indocyanine green (ICG)-conjugated recombinant human chorionic gonadotropin (hCG) protein target early follicles with long-term effectiveness. A novel...
Abstract Recently, photothermal therapy (PTT) has attracted enormous attention because of its low invasiveness, high spatiotemporal selectivity, and good therapeutic effect. Different types conversion agents have been developed, particularly the second near‐infrared window (NIR‐II, 1000–1700 nm) organic small molecular dyes which become an attractive research direction. Herein, a novel simple donor–acceptor–donor (D–A–D) type NIR‐II dye SeC is designed synthesized with...
Nowadays, second near-infrared window (NIR-II) dyes' development focuses on pursuing a longer absorption/emission wavelength and higher quantum yield, which usually means an extended π conjugation system, resulting in enormous molecular weight poor druggability. Most researchers thought that the reduced system would bring blueshift spectrum causes dim imaging qualities. Little efforts have been made to study smaller NIR-II dyes with system. Herein, we synthesized donor–acceptor (D-A) probe...
As one of the research hotspots in recent years, gut microbiota have been proven to be closely related host metabolism, nutrient absorption, and immune regulation. However, there are still many urgent issues microbiota, such as localization tracking microbiota. In this research, two new fluorescent probes, EF 6F, were developed by optimizing structure positron salt small molecule probe F16.
Background Predicting flap viability benefits patients by reducing complications and guides design donor areas. Due to varying anatomy, obtaining individual vascular information preoperatively is fundamental for designing safe flaps. Although indocyanine green angiography (ICGA) a conventional tool in intraoperative assessment postoperative monitoring, it rare preoperative prediction. Methods ICGA was performed on 20 male BALB/c mice under five wavelengths (900/1,000/1,100, /1,250/1,450 nm)...