Cleto Álvarez-Aguilar

ORCID: 0000-0002-1608-1808
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Hormonal Regulation and Hypertension
  • Dialysis and Renal Disease Management
  • Health and Lifestyle Studies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Renin-Angiotensin System Studies
  • Regulation of Appetite and Obesity
  • Renal Transplantation Outcomes and Treatments
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Diet and metabolism studies
  • Genetic Associations and Epidemiology
  • Chronic Kidney Disease and Diabetes
  • Adipokines, Inflammation, and Metabolic Diseases
  • Biochemical Analysis and Sensing Techniques
  • RNA Interference and Gene Delivery
  • Sodium Intake and Health
  • Cancer-related gene regulation
  • Climate Change and Health Impacts
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiovascular Health and Risk Factors
  • Apelin-related biomedical research
  • Artificial Intelligence in Healthcare
  • Advanced Glycation End Products research
  • Acute Myocardial Infarction Research

Universidad Michoacana de San Nicolás de Hidalgo
2013-2025

Asociación Colombiana de Nefrología e Hipertensión Arterial
2025

Universidad de Morelia
2007-2021

Mexican Social Security Institute
2007-2018

Centro Medico Nacional Siglo XXI
2005-2007

Hospital de Especialidades
2005

Knowledge about the immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, particularly regarding function of eosinophils, has been steadily emerging recently. There exists controversy implications eosinophils in disease 2019 (COVID-19)'s pathology. We report a retrospective cohort study including comparison leukocyte counts COVID-19 patients, considering outcomes recovery (n = 59) and death 60). Among different types leukocytes, eosinophil were...

10.3390/v13091675 article EN cc-by Viruses 2021-08-24

Abstract The May Measurement Month (MMM) campaign was carried out in Mexico 2022 with the aim of raising awareness raised blood pressure (BP). Here, we report on findings campaign. Adults aged ≥ 18 years were recruited opportunistically at first-contact health centers several states Mexican Republic. Three seated BP readings taken for each participant, along completion a questionnaire demographics, lifestyle factors, and comorbidities. Hypertension defined as systolic 140 mmHg and/or...

10.1093/eurheartjsupp/suaf041 article EN cc-by-nc European Heart Journal Supplements 2025-02-12

Patients with end-stage renal disease (ESRD) are at increased risk of cardiovascular (CVD), such as myocardial infarction (MI). Uremic toxins and endothelial dysfunction central to this process. In exploratory study, we used the Affymetrix GeneChip microarray investigate gene expression profile in uremic serum-induced human coronary arterial cells (HCAECs) from ESRD patients without MI (UWI UWOI groups) an approach its underlying mechanism. We also explored which pathways involved found 100...

10.3390/ijms26083732 article EN International Journal of Molecular Sciences 2025-04-15

Chronic Kidney Disease (CKD) is a serious public health problem. Hyperglycemia stimulates the production of reactive oxygen species that cause oxidative damage to proteins. AOPPs constitute group oxidized dityrosine-containing proteins are generated during periods stress. They have proved be valuable early marker tissue and active mediators inflammation associated with uremic state. To analyze if advanced protein products (AOPPs) diagnostic accuracy for identifying chronic kidney disease in...

10.3390/metabo14010037 article EN cc-by Metabolites 2024-01-07

Metabolic Syndrome (MS) is recognized as a cluster of cardiovascular risk factors. All components MS have genetic base. Genes the renin angiotensin system are potential candidate genes for MS. We investigated whether converting enzyme (ACE) gene polymorphism increases susceptibility to an entity in Mexican population. In cross-sectional study, 514 individuals were studied including 245 patients with and 269 subjects without criteria. ACE was detected using PCR. defined according The National...

10.1038/emm.2007.36 article EN cc-by Experimental & Molecular Medicine 2007-06-01
Miguel Vázquez‐Moreno Helen Zeng Daniel Locia‐Morales Jesús Peralta‐Romero Hamza Asif and 60 more Arjuna Maharaj Vivian Tam María del Socorro Romero-Figueroa Gloria Patricia Sosa-Bustamante Socorro Méndez‐Martínez Aurora Mejía‐Benítez Adán Valladares‐Salgado Niels H. Wacher Andrea Socorro Álvarez Villaseñor Kelly G Acosta Raquel Flores-Torrecillas Uriel Flores-Osuna Mariell G García-Avilés Roxana González‐Dzib René A Gameros-Gardea María Luisa Pizano-Zárate Jorge A. Núñez-Hernández Verónica de León-Camacho Roberto Karam-Araujo Perla Corona-Salazar Fernando Suárez‐Sánchez Jaime Gómez-Zamudio Eugenia Flores‐Alfaro Arturo Reyes-Hernández Catalina Peralta-Cortázar Emmanuel G Martínez-Moralesvalla Luz V Díaz de León Morales Irma L del C González-González Arturo Maximiliano Reyes-Sosa Sonia Lazcano-Bautista María Georgina Arteaga-Alcaraz Nandy García-Silva Moisés Herrera-Lemus Gress Marissell Gómez Arteaga Anel Gómez‐García Martha V Urbina-Treviño Diana Carolina Villalpando Sánchez Cleto Álvarez-Aguilar Ramón Ernesto Jiménez-Arredondo Martha I. Dávila‐Rodríguez Francisco González‐Salazar Laura Hermila de la Garza-Salinas Aleyda Pérez‐Herrera Jorge Martínez-Torres Elizabeth Méndez-Fernández Víctor A. Segura-Bonilla Mariana Gutiérrez-Hernández Lilia Susana Gallardo-Vidal Leticia Blanco Castillo José J. García-González Julio Medina‐Serrano Adrián Canizalez‐Roman Cruz Mónica López-Morales Jaime Valle-Leal Martin Segura-Chico Rafael Violenté-Ortiz Verónica Fernández-Jiménez Norma A Sánchez-Hernández Miguel Cruz David Meyre

Abstract Context Rare partial/complete loss-of-function mutations in the melanocortin-4 receptor (MC4R) gene are most common cause of Mendelian obesity European populations, but their contribution to Mexican population is unclear. Objective and Design We investigated whether deleterious MC4R contribute children adults. Results provide evidence that p.Ile269Asn (rs79783591) mutation may have arisen modern human populations from a founder event native Mexicans. The Isoleucine 269 perfectly...

10.1210/clinem/dgz276 article EN The Journal of Clinical Endocrinology & Metabolism 2019-12-16

Background: A reduction of dopaminergic (DAergic) activity with increased prolactin levels has been found in obese and hypertensive patients, suggesting its involvement as a pathophysiological mechanism promoting hypertension. Similarly, leptin action increasing sympathetic proposed to be involved mechanisms The aim this study was analyze the effects DA, norepinephrine (NE), on release gene ( OB ) expression adipocytes from patients. Methods: Leptin were analyzed cultured 16 patients treated...

10.2147/ijnrd.s50664 article EN cc-by-nc International Journal of Nephrology and Renovascular Disease 2013-11-01

Background Arterial hypertension is highly prevalent in Mexico; nevertheless, there are limited insights regarding its management during the COVID-19 pandemic. Here, we estimate prevalence of clinical and treatment profiles arterial explore associated factors for undiagnosed uncontrolled using a cross-sectional survey endorsed by Collaborative Group on Hypertension from Mexican Institute Social Security. Methods Our was conducted May to November 2021 May-Measurement Month protocols...

10.3389/fpubh.2024.1385349 article EN cc-by Frontiers in Public Health 2024-07-12

Abstract Background Artificial intelligence (AI) models applied to diabetes mellitus research have grown in recent years, particularly the field of medical imaging. However little work has been done exploring real-world data (RWD) sources such as electronic health records (EHR) mostly due lack reliable public databases. However, with more than 500 million patients affected worldwide, complications this condition catastrophic consequences. In manuscript we aim first extract, clean and...

10.1101/2023.10.22.23297277 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2023-10-23
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