A5045226074- Proteoglycans and glycosaminoglycans research
- Polysaccharides and Plant Cell Walls
- Cancer-related molecular mechanisms research
- Seaweed-derived Bioactive Compounds
- Peptidase Inhibition and Analysis
- Circular RNAs in diseases
- Cancer Research and Treatments
- Radiopharmaceutical Chemistry and Applications
- Phytochemical Studies and Bioactivities
- Mycobacterium research and diagnosis
- Phagocytosis and Immune Regulation
- Advanced Chemical Sensor Technologies
- Immunotherapy and Immune Responses
- Medical Imaging Techniques and Applications
- Antimicrobial Peptides and Activities
- Phytochemistry and Bioactive Compounds
- MicroRNA in disease regulation
- RNA modifications and cancer
- Cardiac tumors and thrombi
- Viral Infectious Diseases and Gene Expression in Insects
- Hepatocellular Carcinoma Treatment and Prognosis
- Analytical Chemistry and Chromatography
- Meat and Animal Product Quality
- Carbohydrate Chemistry and Synthesis
- Pancreatic and Hepatic Oncology Research
Fujian Medical University
2021-2024
First Affiliated Hospital of Fujian Medical University
2021-2024
Bengbu Medical College
2008-2024
Bengbu University
2024
Nanjing Agricultural University
2008-2015
Institute of Food Science & Technology
2015
Zhejiang University
2007
Abstract Emerging evidences suggest that long noncoding RNA (lncRNA) plays a vital role in tumorigenesis and cancer progression. Here, the aim of this study is to investigate biological function intervening Linc00284 colorectal (CRC). The expression levels Linc00284, miR-27a c-Met were evaluated by qPCR and/or Western blotting. Immunohistochemistry was used detect Ki67 Phh3 tumor tissues. interaction between validated luciferase reporter assay immunoprecipitation (RIP) assay. Cell...
Recombinant Listeria monocytogenes mutants carrying Newcastle disease virus (NDV) fusion protein gene F were constructed by homologous recombination. NDV or its truncated fragment Fa was used as the model heterologous to be integrated into actA plcB downstream of their signal sequences. Correct orientation inserted genes verified polymerase chain reaction amplification Fa. The and expressed in two recombinants Lm-DeltaactA-F Lm-DeltaplcB-Fa shown sodium dodecylsulfate-polyacrylamide gel...
<italic>Hyriopsis cumingii</italic> polysaccharides (HCPS) showed anti-angiogenic activity and promoting effects on the chemotaxis, proliferation phagocytosis of peritoneal macrophage.
This study investigated the clinical and functional significance of circ-AKT3 in hepatocellular carcinoma (HCC) its impact on tumor progression. Using qRT-PCR, we found reduced levels HCC tissues compared to adjacent liver samples. Clinical data revealed that low expression correlated with increased lymphatic distant metastasis. Functional experiments MHCC-97H Hep3B cells, chosen due their levels, demonstrated overexpression suppressed cell proliferation, invasion, migration. Bioinformatics...
Abstract Background: Colorectal cancer (CRC) is a common malignant neoplasm, and the cluster of differentiation 47 (CD47) an innate immune checkpoint promising diagnostic therapeutic target. We comprehensively examined potential prognostic value, clinicopathological characteristics, infiltration associated with CD47 in CRC patients. Results: In total, 305 differentially expressed genes (DEGs) were identified. The receiver operating characteristic (ROC) curve analysis suggested area under ROC...
Radioresistance is the leading cause of failed radiation therapy for pancreatic ductal cancer (PDAC). The relevance cationic trypsinogen gene (PRSS1) in PDAC radioresistance unknown, despite its association with tumor responses to numerous malignancies. Here we established two PRSS1 point mutation cell lines: c. 338 T > G and c.410 C T. Compared their parental cells, elevated AKT ERK phosphorylation concentrations were observed Panc-1 MIA PaCa-2 cells mutations. restored sensitivity...