- Plant Pathogens and Fungal Diseases
- Mycotoxins in Agriculture and Food
- Plant-Microbe Interactions and Immunity
- Fungal and yeast genetics research
- Esophageal Cancer Research and Treatment
- Microbial Natural Products and Biosynthesis
- Entomopathogenic Microorganisms in Pest Control
- Gastric Cancer Management and Outcomes
- Fungal Biology and Applications
- Studies on Chitinases and Chitosanases
- Heat shock proteins research
- Gastrointestinal Tumor Research and Treatment
- Plant Disease Management Techniques
- Plant Reproductive Biology
- Plant Pathogenic Bacteria Studies
- Plant Disease Resistance and Genetics
- Genomics and Phylogenetic Studies
- Gastrointestinal disorders and treatments
- Connexins and lens biology
- Polysaccharides and Plant Cell Walls
- Mycorrhizal Fungi and Plant Interactions
- Fungal Plant Pathogen Control
- Plant tissue culture and regeneration
- Cancer-related molecular mechanisms research
- Plant Pathogens and Resistance
Tianjin Agricultural University
2019-2025
Shanxi Provincial Cancer Hospital
2021-2023
Institute of Vegetables and Flowers
2014-2016
Chinese Academy of Agricultural Sciences
2014-2016
Purpureocillium lilacinum of Ophiocordycipitaceae is one the most promising and commercialized agents for controlling plant parasitic nematodes, as well other insects pathogens. However, how fungus functions at molecular level remains unknown. Here, we sequenced two isolates (PLBJ-1 PLFJ-1) P. from different places Beijing Fujian. Genomic analysis showed high synteny isolates, phylogenetic indicated they were related to insect pathogen Tolypocladium inflatum. A comparison with species...
Fusarium oxysporum is a soil-born fungus that induces wilt and root rot on variety of plants. F. f. sp. conglutinans (Foc) can cause disease cabbage. This study showed homolog SIX1 protein in the Arabidopsis infecting isolate Fo5176 (Fo5176-SIX1) had four isoforms conidia Foc by proteomic analysis. Thus, we analyzed roles Foc-SIX1. Gene expression analysis that, compared to mycelia, dramatically altered Foc-SIX1 could be detected after cabbages, was highly expressed under axenic culture...
Fusarium oxysporum is a soil-inhabiting fungus that induces vascular wilt and root rot in variety of plants. F. f. sp. conglutinans (Foc), which comprises two races, can cause disease cabbage. Compared with race 1 (52557(-TM), R1), 2 (58385(-TM), R2) exhibits much stronger pathogenicity. Here, we provide the first proteome reference maps for Foc mycelium conidia identify 145 proteins different abundances among races. Of these proteins, most high-abundance R2 are involved carbohydrate, amino...
Aspergillus ochraceus is reported to be the major contributor of ochratoxin A (OTA), classified as one possible human carcinogen (group 2B) by International Agency for Research on Cancer. The heterotrimeric velvet complex proteins, LaeA/VeA/VelB, have been most studied in fungi clarify relation between light-dependent morphology and secondary metabolism. To explore genetic targets control OTA contamination, we identified laeA, veA, velB A. ochraceus. loss yielded mutants with differences...
Rab GTPases play a crucial role in facilitating the transportation of vesicles during process fungal biogenesis. Currently, there is limited understanding regarding specific biological functions small GTPase elements within Fusarium oxysporum . In this study, we examined three proteins FoRab5, FoRab7, and FoRab8 Foc, which exhibit homology to protein family found Saccharomyces cerevisiae addition, also employed PEG-mediated homologous recombination approach create deletion mutants...
Introduction Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are plant parasitic with a broad host range, causing substantial economic losses annually. The selection and utilization of novel biological control resources crucial for managing RKNs diseases. Methods This study isolated Candida quercitrusa Cq-C08 from rhizosphere soil, which efficacy against Meloidogyne incognita was investigated through laboratory experiments, pot plot trials, analysis transcriptomic data...
Aspergillus westerdijkiae, the producer of ochratoxin A (OTA), which is worldwide concern, an import fungal species in agriculture, food, and industry. Here, we got uridine auxotrophic mutant A. westerdijkiae by deleting AwpyrG. The ΔAwpyrG could be used for bio-transformation with exogenous AfpyrG expression cassette as a selection marker. In order to enhance efficiency gene targeting, Awku70 Awlig4 were homologously deleted from ΔAwpyrG. efficiencies homologous replacement ΔAwku70 ΔAwlig4...
Cabbage Fusarium Wilt (CFW) is a serious disease caused by oxysporum f. sp. conglutinans in many parts of the world. The use chemical fungicides has placed heavy burden on environment and prone to drug resistance plant pathogens. As method with great potential, biological control attracted attention academics both at home abroad. In this study, we have found that strains B5 B6 had strong inhibitory effect various pathogens significantly inhibited mycelium growth. They were identified as...
Colletotrichum capsici is one of the most important pathogens on chili peppers. Unreasonable application chemical fungicides will lead to threats human and animal health, environmental damage, increased fungicide resistance pathogens. As an alternative strategy, biological control has been paid more attention by academics. In this study, Yb-1 strain was isolated from healthy cucumber leaves, which could significantly restrict mycelium growth C. Botrytis cinerea, with inhibition rates 93.49%...
The Gleditsia sinensis Lam. widely grown in China is a perennial plant with medicinal properties (Zhang et al. 2016). Since 2019, the leaves of G. have exhibited yellowing and wilting, plants gradually become stunted dead Taifeng park Binhai New Area Tianjin (39.02° N; 117.65° E). In this park, there are two types sinensis, one round branch thorns, other flat thorns. thorns did not grow well almost all had disease symptoms. samples were collected on October, 2021 deposited Plant Disease...
Ochratoxins (OTs) are worldwide regulated mycotoxins contaminating a variety of food-environment and agro-environment. Several Aspergillus Pencillium species synthesize OTs from six-gene biosynthetic gene cluster (BGC) to produce the highly toxic final product OTA. Although many studies on OTA-degrading enzymes were performed, high efficiency with strong stability extremely needed, OTA degrading mechanism is poorly understood. The study aimed explore OT-degradation enzyme investigate its...
Fusarium oxysporum f. sp. conglutinans (FOC) is the dominant pathogen of vascular wilt disease on cabbage and other crucifers. Foc-Nto1 was confirmed to be homologous protein Nto1, a subunit NuA3 (nucleosomal acetyltransferase histone H3) complex in Saccharomyces cerevisiae. FOC contains two races, race 1 2. The functions Nto1 both races were investigated through functional genetics analyses. Nto1-deleted mutants decreased conidium production displayed increased sensitivity hydrogen...
Abstract Background : Heterotopic gastric mucosa(HGM)is a congenital anatomical variation. It can occur in various tissues and organs of the gastrointestinal tract. Part HGM appeared as solitary, sessile submucosal lesions covered with normal mucosa, because it was relatively rare, thereby resulting some to be easily missed or misdiagnosed. We report on case heterotopic mucosa propria muscularis. Case presentation A 32-year-old man abdominal distension for one month. Upper endoscopy revealed...